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The map label for this gene is glpD [H]

Identifier: 99081033

GI number: 99081033

Start: 1282229

End: 1283944

Strand: Direct

Name: glpD [H]

Synonym: TM1040_1192

Alternate gene names: 99081033

Gene position: 1282229-1283944 (Clockwise)

Preceding gene: 99081032

Following gene: 99081034

Centisome position: 40.06

GC content: 62.7

Gene sequence:

>1716_bases
ATGCCCGATCAACGAGTGAAAAACTGGCAAAGCCTGTCTGGTGACGGGGCCTTTGACGTCGTGGTCGTGGGCGGTGGCGT
CAATGGGATCGGCACCTACCGGGAGTTGGCGTTGCAGGGATTGCGCGTTCTTCTGGTCGAGCGGGGCGATTTTGCCAGCG
GCTGTAGTGCGGCGCCGTCGCGGATGATCCATGGCGGCCTGCGATATCTGGAGAATGGCGAGTTCGACCTGGTGCGCGAG
AGCCTGCAGGAGCGCGATGCGCTGTTGGTGAACGCGCCGCATTTTGTGCATCCGCTGCCGACGGTTATCCCCGTGACCTC
GCTGTTTTCCGGTCTGTTCAACGCGGCGGCGTCCTTTTGGGGGCTGAGCAGCAAACCAGCGCCGCGTGGTGCGGTGCCGA
TCAAGCTGGGACTGAGCCTTTATGACTGGGTAAGCCGCAAACGCCGCCTGATGCCAAGGCACAGCTTTCAGGGACGCCGC
GCCACCCGCCGCGACTGGCCCGAGCTGATGGAGGAGGCGCGGGGCACCGCGACCTACCATGATGCCTGGATCGGGTTTCC
AGAGCGTCTCTGTATCGAAATGCTTCAGGATGTGGCGCGGGTGGCGCCGGGCTGTGTCGCGCTCAATTATTGCGAGATCG
CAGCGGAGACCGGCGGGTTCAGTGTGACCTGCCAGCGCAGCGGTCAGACCGCAGAGATACGGCCCCGGCTCATTGTCAAC
GCCACGGGAGCCTGGCTGGATGAAACCGTGGCGCAGCTCGGCGGGACGGCGCCGCGGATGGTGGAGGGCACCAAGGGCTC
GCATCTGATTTTGGATCACCCGGAGCTTTTTGCCGCGCTCAAGGGCAATATGGTCTTCTTTGAAAACGATGACGGGCGGG
TCTGTATCGTGTTTCCGTTTCACGATCGGGTGCTGGCGGGCTCGACCGATATACGGGTGGCGCGCACCGGACGCGTGCGC
TGCGAGCCGGAGGAGACCGACTATATCCTCGGTGCGCTCGCGAAAGTGTTTCCGGGGCTGCAGATTGACGCCAGTCAGAT
CGTGTTCAGCTATTCCGGAATCCGGCCCTTGCCGCAGAGCGACCAGGATTTTACCGGCCGGATTTCGCGCGGCCACGACA
TTCGCAAACTGGAGGGCAGGGTGCCCCAGCTCTGCATGATCGGTGGCAAATGGACCACCTTTCGCGCTTTTGCGCAGCAG
ACGGCAGATGCAGCGCTCGGGGAGCTTCGGCACGGTCGGCGCGTTGATACGCTGGATCTGGCGATTGGGGGCGGGGCGAA
GTTTGAAGGGCGAGAAGCCCAGATCCTGCAGGAGCTTTGCAAGGTACAAAACCTCAGCCACGCCCGCGCCGGTCATCTCT
TGCAGCGCTACGGCAGCCATGCCCCCAAGGTCGCAATCGCCTGTGGTCGCGAGGACCGCCCGCTGGCCGCAGGGACGCTC
TATTCCGAGGGCGAGATCCTGCACCTTATCCGAAGCGAGTTTGTCGAAACCCTATCGGATCTGGCCCTTCGGCGCACGGA
TCTGGCGATCTCTGGCGTGCTCTCGATGCAGATCATCGAGGCGCTGGCGGCGCTGATGGCGCAGGAAACGGGTCTCTCGC
CTGATCTCATCACGGCTCAGAAACAGGATCTGATTGCAGAGCTGAGCACCTATCACGGCGTAACCGCCGCAACTCTTGAA
CGTCGAAATACCGAAAGGAATGCCCAATGCGCATGA

Upstream 100 bases:

>100_bases
CACGCATCTCAGCGACCTCGACGGCTGATTCACAGGCCCTGACGCCACCACATGACATGCACAAAACGCTGCGACGACCT
CGTCAGCGCACGGAGAAGAT

Downstream 100 bases:

>100_bases
GCATGAAAGCCCGCATGAACCGGATGTTTAGCAACGGTGGTTGTCTGGACGTGGCCATCGACCATGGTGTCTGCAACGAA
CCGAGCTTCATGGTTGGTCT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MPDQRVKNWQSLSGDGAFDVVVVGGGVNGIGTYRELALQGLRVLLVERGDFASGCSAAPSRMIHGGLRYLENGEFDLVRE
SLQERDALLVNAPHFVHPLPTVIPVTSLFSGLFNAAASFWGLSSKPAPRGAVPIKLGLSLYDWVSRKRRLMPRHSFQGRR
ATRRDWPELMEEARGTATYHDAWIGFPERLCIEMLQDVARVAPGCVALNYCEIAAETGGFSVTCQRSGQTAEIRPRLIVN
ATGAWLDETVAQLGGTAPRMVEGTKGSHLILDHPELFAALKGNMVFFENDDGRVCIVFPFHDRVLAGSTDIRVARTGRVR
CEPEETDYILGALAKVFPGLQIDASQIVFSYSGIRPLPQSDQDFTGRISRGHDIRKLEGRVPQLCMIGGKWTTFRAFAQQ
TADAALGELRHGRRVDTLDLAIGGGAKFEGREAQILQELCKVQNLSHARAGHLLQRYGSHAPKVAIACGREDRPLAAGTL
YSEGEILHLIRSEFVETLSDLALRRTDLAISGVLSMQIIEALAALMAQETGLSPDLITAQKQDLIAELSTYHGVTAATLE
RRNTERNAQCA

Sequences:

>Translated_571_residues
MPDQRVKNWQSLSGDGAFDVVVVGGGVNGIGTYRELALQGLRVLLVERGDFASGCSAAPSRMIHGGLRYLENGEFDLVRE
SLQERDALLVNAPHFVHPLPTVIPVTSLFSGLFNAAASFWGLSSKPAPRGAVPIKLGLSLYDWVSRKRRLMPRHSFQGRR
ATRRDWPELMEEARGTATYHDAWIGFPERLCIEMLQDVARVAPGCVALNYCEIAAETGGFSVTCQRSGQTAEIRPRLIVN
ATGAWLDETVAQLGGTAPRMVEGTKGSHLILDHPELFAALKGNMVFFENDDGRVCIVFPFHDRVLAGSTDIRVARTGRVR
CEPEETDYILGALAKVFPGLQIDASQIVFSYSGIRPLPQSDQDFTGRISRGHDIRKLEGRVPQLCMIGGKWTTFRAFAQQ
TADAALGELRHGRRVDTLDLAIGGGAKFEGREAQILQELCKVQNLSHARAGHLLQRYGSHAPKVAIACGREDRPLAAGTL
YSEGEILHLIRSEFVETLSDLALRRTDLAISGVLSMQIIEALAALMAQETGLSPDLITAQKQDLIAELSTYHGVTAATLE
RRNTERNAQCA
>Mature_570_residues
PDQRVKNWQSLSGDGAFDVVVVGGGVNGIGTYRELALQGLRVLLVERGDFASGCSAAPSRMIHGGLRYLENGEFDLVRES
LQERDALLVNAPHFVHPLPTVIPVTSLFSGLFNAAASFWGLSSKPAPRGAVPIKLGLSLYDWVSRKRRLMPRHSFQGRRA
TRRDWPELMEEARGTATYHDAWIGFPERLCIEMLQDVARVAPGCVALNYCEIAAETGGFSVTCQRSGQTAEIRPRLIVNA
TGAWLDETVAQLGGTAPRMVEGTKGSHLILDHPELFAALKGNMVFFENDDGRVCIVFPFHDRVLAGSTDIRVARTGRVRC
EPEETDYILGALAKVFPGLQIDASQIVFSYSGIRPLPQSDQDFTGRISRGHDIRKLEGRVPQLCMIGGKWTTFRAFAQQT
ADAALGELRHGRRVDTLDLAIGGGAKFEGREAQILQELCKVQNLSHARAGHLLQRYGSHAPKVAIACGREDRPLAAGTLY
SEGEILHLIRSEFVETLSDLALRRTDLAISGVLSMQIIEALAALMAQETGLSPDLITAQKQDLIAELSTYHGVTAATLER
RNTERNAQCA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=600, Percent_Identity=26.8333333333333, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI285002231, Length=600, Percent_Identity=26.8333333333333, Blast_Score=166, Evalue=5e-41,
Organism=Escherichia coli, GI2367226, Length=476, Percent_Identity=27.9411764705882, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788574, Length=536, Percent_Identity=27.2388059701493, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534726, Length=552, Percent_Identity=26.0869565217391, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17509253, Length=557, Percent_Identity=27.8276481149013, Blast_Score=143, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322036, Length=604, Percent_Identity=25.9933774834437, Blast_Score=146, Evalue=9e-36,
Organism=Drosophila melanogaster, GI161077125, Length=564, Percent_Identity=27.1276595744681, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24653942, Length=564, Percent_Identity=27.1276595744681, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24653944, Length=564, Percent_Identity=27.1276595744681, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20130025, Length=564, Percent_Identity=27.1276595744681, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24586295, Length=556, Percent_Identity=25.8992805755396, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI19921278, Length=564, Percent_Identity=24.822695035461, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62458; Mature: 62327

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQRVKNWQSLSGDGAFDVVVVGGGVNGIGTYRELALQGLRVLLVERGDFASGCSAAPS
CCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCHHEEEEECCCCCCCCCCCHH
RMIHGGLRYLENGEFDLVRESLQERDALLVNAPHFVHPLPTVIPVTSLFSGLFNAAASFW
HHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHC
GLSSKPAPRGAVPIKLGLSLYDWVSRKRRLMPRHSFQGRRATRRDWPELMEEARGTATYH
CCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEC
DAWIGFPERLCIEMLQDVARVAPGCVALNYCEIAAETGGFSVTCQRSGQTAEIRPRLIVN
HHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHEECCCCEEEEEECCCCCCCCCCEEEEE
ATGAWLDETVAQLGGTAPRMVEGTKGSHLILDHPELFAALKGNMVFFENDDGRVCIVFPF
CCCCHHHHHHHHHCCCCCCEEECCCCCEEEEECHHHHHHHCCCEEEEECCCCCEEEEEEC
HDRVLAGSTDIRVARTGRVRCEPEETDYILGALAKVFPGLQIDASQIVFSYSGIRPLPQS
CCEEECCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCEECHHHHEEEECCCCCCCCC
DQDFTGRISRGHDIRKLEGRVPQLCMIGGKWTTFRAFAQQTADAALGELRHGRRVDTLDL
CCCCCCCCCCCCCHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AIGGGAKFEGREAQILQELCKVQNLSHARAGHLLQRYGSHAPKVAIACGREDRPLAAGTL
EECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEE
YSEGEILHLIRSEFVETLSDLALRRTDLAISGVLSMQIIEALAALMAQETGLSPDLITAQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KQDLIAELSTYHGVTAATLERRNTERNAQCA
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PDQRVKNWQSLSGDGAFDVVVVGGGVNGIGTYRELALQGLRVLLVERGDFASGCSAAPS
CCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCHHEEEEECCCCCCCCCCCHH
RMIHGGLRYLENGEFDLVRESLQERDALLVNAPHFVHPLPTVIPVTSLFSGLFNAAASFW
HHHHHHHHHHCCCCHHHHHHHHHHCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHC
GLSSKPAPRGAVPIKLGLSLYDWVSRKRRLMPRHSFQGRRATRRDWPELMEEARGTATYH
CCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEC
DAWIGFPERLCIEMLQDVARVAPGCVALNYCEIAAETGGFSVTCQRSGQTAEIRPRLIVN
HHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHEECCCCEEEEEECCCCCCCCCCEEEEE
ATGAWLDETVAQLGGTAPRMVEGTKGSHLILDHPELFAALKGNMVFFENDDGRVCIVFPF
CCCCHHHHHHHHHCCCCCCEEECCCCCEEEEECHHHHHHHCCCEEEEECCCCCEEEEEEC
HDRVLAGSTDIRVARTGRVRCEPEETDYILGALAKVFPGLQIDASQIVFSYSGIRPLPQS
CCEEECCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCEECHHHHEEEECCCCCCCCC
DQDFTGRISRGHDIRKLEGRVPQLCMIGGKWTTFRAFAQQTADAALGELRHGRRVDTLDL
CCCCCCCCCCCCCHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AIGGGAKFEGREAQILQELCKVQNLSHARAGHLLQRYGSHAPKVAIACGREDRPLAAGTL
EECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEE
YSEGEILHLIRSEFVETLSDLALRRTDLAISGVLSMQIIEALAALMAQETGLSPDLITAQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
KQDLIAELSTYHGVTAATLERRNTERNAQCA
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]