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The map label for this gene is lsrR [H]

Identifier: 99081031

GI number: 99081031

Start: 1280191

End: 1281171

Strand: Direct

Name: lsrR [H]

Synonym: TM1040_1190

Alternate gene names: 99081031

Gene position: 1280191-1281171 (Clockwise)

Preceding gene: 99081030

Following gene: 99081032

Centisome position: 39.99

GC content: 60.65

Gene sequence:

>981_bases
ATGGTTGAGCACAGACAAGGGTTCGAAACCGTCCGCCAGATCCACACTGTTTTGGTCCTTCATTTTATCGAGGGCAAGAA
ACAGTCGGAGATCGCGACCGAACTGAACCTCTCCACATCCAAGGTGAACCGGCTGATCTCTCAGGGGCGCAAGCTGGGCA
TGCTGAAGATCGAGATCGAGAGCCCGTTTCAGCGGCTCATGGACATTGAGGAGGCCGTCACCCGCTTTGCCAATCTCGGC
AGCGCCGTTGTGACGCCGACCGTGGAGGGCAGCGAAAAAGCGACGCTGCAGCAGGTTGGCCGCGCTGCGGCTAGCCACCT
GACCGAGACGCTGCGCGATGGCGATGTCATTGCGATTACCGGTGGCAAGGCGGTGAGCGCCCTGGTCGATGGACTTGATG
TGGAGCGGCAATGGGACGTGACCGTTGTGCCGCTCACAGGGGGGGTGCAGGGCAAATATTTCACCGACGTTAACCACCTC
GCCACCCGGTTGGCTGAACGTCTGGGGGGCAAGACCATGCTGCTGCATGCGCCGCTCTTTGCCGAAAGCAAGGCCCAGCG
CGACATGCTGATGGATATTTCCTCCATCAAGGAAGTGCTCGATCTGGCCCGTCGCGCCAATGTGGCGCTTGTGGGGATCG
GCTCCGTGCAGCCAGCGGAATCAAGCTATTACGACCTCCACCCGGTGCCGGAAGCCGATCGCAAGATGCTTGTGGGCACC
GGTGTTGTGGGCGAGTTCATGGGCCATCTGATCCGCGACAATGGTGCGGTGGCCAATTTCGCCCTTAACTCGCGCCTCGT
GGCCCTGTCGCCACAGGAACTGGGCCAATGTGAGCGCGTGATCGGGATCGCGGCGGGCGCCAGCAAGGTGCGCCCCATCG
AGGCGGCGCTTGAAGGCGGGTTTCTGAGCTCGCTCATCGTTGACGAAGACACGGCCGCAGAAGTGCTGCAGAAATATGAA
GGAACTGAATATGTCGCATGA

Upstream 100 bases:

>100_bases
GATGTGTCGGTCTACTGGCAGGACATCATCCGGGGGTCGATCCTTCTGGCGGCGGTGACAATCGACCACTTCCTCAACAA
GAAGCGGGGCTGAGGGGGAT

Downstream 100 bases:

>100_bases
AATGCTGAAACGTGAGATCGGCCGCTCCGGGATCGAGGCTTCGGCCATCGGGCTTGGCACCTGGGCCATTGGCGGCTGGA
TGTGGGGTGGCACGGATGAG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MVEHRQGFETVRQIHTVLVLHFIEGKKQSEIATELNLSTSKVNRLISQGRKLGMLKIEIESPFQRLMDIEEAVTRFANLG
SAVVTPTVEGSEKATLQQVGRAAASHLTETLRDGDVIAITGGKAVSALVDGLDVERQWDVTVVPLTGGVQGKYFTDVNHL
ATRLAERLGGKTMLLHAPLFAESKAQRDMLMDISSIKEVLDLARRANVALVGIGSVQPAESSYYDLHPVPEADRKMLVGT
GVVGEFMGHLIRDNGAVANFALNSRLVALSPQELGQCERVIGIAAGASKVRPIEAALEGGFLSSLIVDEDTAAEVLQKYE
GTEYVA

Sequences:

>Translated_326_residues
MVEHRQGFETVRQIHTVLVLHFIEGKKQSEIATELNLSTSKVNRLISQGRKLGMLKIEIESPFQRLMDIEEAVTRFANLG
SAVVTPTVEGSEKATLQQVGRAAASHLTETLRDGDVIAITGGKAVSALVDGLDVERQWDVTVVPLTGGVQGKYFTDVNHL
ATRLAERLGGKTMLLHAPLFAESKAQRDMLMDISSIKEVLDLARRANVALVGIGSVQPAESSYYDLHPVPEADRKMLVGT
GVVGEFMGHLIRDNGAVANFALNSRLVALSPQELGQCERVIGIAAGASKVRPIEAALEGGFLSSLIVDEDTAAEVLQKYE
GTEYVA
>Mature_326_residues
MVEHRQGFETVRQIHTVLVLHFIEGKKQSEIATELNLSTSKVNRLISQGRKLGMLKIEIESPFQRLMDIEEAVTRFANLG
SAVVTPTVEGSEKATLQQVGRAAASHLTETLRDGDVIAITGGKAVSALVDGLDVERQWDVTVVPLTGGVQGKYFTDVNHL
ATRLAERLGGKTMLLHAPLFAESKAQRDMLMDISSIKEVLDLARRANVALVGIGSVQPAESSYYDLHPVPEADRKMLVGT
GVVGEFMGHLIRDNGAVANFALNSRLVALSPQELGQCERVIGIAAGASKVRPIEAALEGGFLSSLIVDEDTAAEVLQKYE
GTEYVA

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=316, Percent_Identity=28.4810126582279, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87082414, Length=302, Percent_Identity=22.8476821192053, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35181; Mature: 35181

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEHRQGFETVRQIHTVLVLHFIEGKKQSEIATELNLSTSKVNRLISQGRKLGMLKIEIE
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEC
SPFQRLMDIEEAVTRFANLGSAVVTPTVEGSEKATLQQVGRAAASHLTETLRDGDVIAIT
CHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GGKAVSALVDGLDVERQWDVTVVPLTGGVQGKYFTDVNHLATRLAERLGGKTMLLHAPLF
CCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCHH
AESKAQRDMLMDISSIKEVLDLARRANVALVGIGSVQPAESSYYDLHPVPEADRKMLVGT
HCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCCCCCEEEEEC
GVVGEFMGHLIRDNGAVANFALNSRLVALSPQELGQCERVIGIAAGASKVRPIEAALEGG
CHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
FLSSLIVDEDTAAEVLQKYEGTEYVA
HHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVEHRQGFETVRQIHTVLVLHFIEGKKQSEIATELNLSTSKVNRLISQGRKLGMLKIEIE
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEC
SPFQRLMDIEEAVTRFANLGSAVVTPTVEGSEKATLQQVGRAAASHLTETLRDGDVIAIT
CHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GGKAVSALVDGLDVERQWDVTVVPLTGGVQGKYFTDVNHLATRLAERLGGKTMLLHAPLF
CCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCHH
AESKAQRDMLMDISSIKEVLDLARRANVALVGIGSVQPAESSYYDLHPVPEADRKMLVGT
HCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCCCCCEEEEEC
GVVGEFMGHLIRDNGAVANFALNSRLVALSPQELGQCERVIGIAAGASKVRPIEAALEGG
CHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
FLSSLIVDEDTAAEVLQKYEGTEYVA
HHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA