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The map label for this gene is coaD

Identifier: 99080950

GI number: 99080950

Start: 1191220

End: 1191717

Strand: Direct

Name: coaD

Synonym: TM1040_1109

Alternate gene names: 99080950

Gene position: 1191220-1191717 (Clockwise)

Preceding gene: 99080949

Following gene: 99080953

Centisome position: 37.21

GC content: 60.44

Gene sequence:

>498_bases
ATGCGCATTGGCTTGTATCCCGGAACCTTTGACCCCATCACCTTGGGGCATATCGACATTATCCGGCGGGCAACCCTGCT
GGTAGACCGGCTTGTGATCGGCGTGGCGATCAATCGCGACAAGGGACCGTTGTTCGATCTCGAAGAGCGCGTCGCCATGA
TCGAGGCAGAGTGCGCCAAGCTCACCGAGCAGACCGGCACCGAGATCGTCGTCCACCCGTTTGAGAATCTGCTGATTGAC
TGCGCCCGCGATGTGGGCGCGCAGGTGATTGTGCGCGGTCTGCGCGCGGTTGCGGATTTTGAATATGAATTCCAGATGGT
TGGCATGAACCGCGCGCTCGATGACAGCATCGAGACGGTGTTCCTCATGGCTGAGGCCCGCCATCAGGCCATCGCCAGCA
AACTGGTCAAGGAAATCTCGCGCCTCGGGGGCGATGTCAGCAAGTTTGTGACGCCTCTTGTGCGCGAACGCCTCGCAGAG
CGTCTGGGCCAGCGCTAG

Upstream 100 bases:

>100_bases
CGATTATGCACTGGCTGAAGATTCAGTATTCTCACGCACTTGCATTGCGTCGCGCAACATGATTGCGTGCCCGGGAATGT
GACGCAGGCAGGAGGGGCCC

Downstream 100 bases:

>100_bases
GCCCCAGCCAGTCCATTTGGAACACTTGGATCCGGTCTGCCGCGCGCGGGCCGGTTTTGCTTTGTGGTCAGCGCCAGAAA
GCGAGCCACTCGATCAGCTC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRIGLYPGTFDPITLGHIDIIRRATLLVDRLVIGVAINRDKGPLFDLEERVAMIEAECAKLTEQTGTEIVVHPFENLLID
CARDVGAQVIVRGLRAVADFEYEFQMVGMNRALDDSIETVFLMAEARHQAIASKLVKEISRLGGDVSKFVTPLVRERLAE
RLGQR

Sequences:

>Translated_165_residues
MRIGLYPGTFDPITLGHIDIIRRATLLVDRLVIGVAINRDKGPLFDLEERVAMIEAECAKLTEQTGTEIVVHPFENLLID
CARDVGAQVIVRGLRAVADFEYEFQMVGMNRALDDSIETVFLMAEARHQAIASKLVKEISRLGGDVSKFVTPLVRERLAE
RLGQR
>Mature_165_residues
MRIGLYPGTFDPITLGHIDIIRRATLLVDRLVIGVAINRDKGPLFDLEERVAMIEAECAKLTEQTGTEIVVHPFENLLID
CARDVGAQVIVRGLRAVADFEYEFQMVGMNRALDDSIETVFLMAEARHQAIASKLVKEISRLGGDVSKFVTPLVRERLAE
RLGQR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=160, Percent_Identity=46.25, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_SILST (Q1GHM4)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613104.1
- ProteinModelPortal:   Q1GHM4
- SMR:   Q1GHM4
- STRING:   Q1GHM4
- GeneID:   4077816
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1109
- NMPDR:   fig|292414.1.peg.3756
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q1GHM4
- ProtClustDB:   PRK00168
- BioCyc:   SSP292414:TM1040_1109-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18446; Mature: 18446

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGLYPGTFDPITLGHIDIIRRATLLVDRLVIGVAINRDKGPLFDLEERVAMIEAECAK
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHH
LTEQTGTEIVVHPFENLLIDCARDVGAQVIVRGLRAVADFEYEFQMVGMNRALDDSIETV
HHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCHHHHHHHHHH
FLMAEARHQAIASKLVKEISRLGGDVSKFVTPLVRERLAERLGQR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIGLYPGTFDPITLGHIDIIRRATLLVDRLVIGVAINRDKGPLFDLEERVAMIEAECAK
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHH
LTEQTGTEIVVHPFENLLIDCARDVGAQVIVRGLRAVADFEYEFQMVGMNRALDDSIETV
HHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCHHHHHHHHHH
FLMAEARHQAIASKLVKEISRLGGDVSKFVTPLVRERLAERLGQR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA