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The map label for this gene is abgR [H]

Identifier: 99080948

GI number: 99080948

Start: 1189708

End: 1190604

Strand: Direct

Name: abgR [H]

Synonym: TM1040_1107

Alternate gene names: 99080948

Gene position: 1189708-1190604 (Clockwise)

Preceding gene: 99080945

Following gene: 99080949

Centisome position: 37.17

GC content: 60.98

Gene sequence:

>897_bases
ATGGAACCCCAATGGGACGATATGAAAGTGTTTTTGGCGGTCGCGCGGGAGAGCAGCCTCTCTGGCGCGGGGCGGGTCCT
CAAGATGGACCCTGCCACAGTGGGCCGCCGGGTGGCCCGGTTTGAGGCCGCGCTCAAGACATCTCTCTTTGTAAAATCAC
CGCAAGGCTATGCGCTGAGCGCGGCCGGAGACAGGCTCTTGGGGCATGCGGAAGCGGCGGAACTCGCCATGCGGGCGGGC
GAAGAGGCGCTCACTGGCCCGAGTGACACGCTTTCGGGGCAGATCCGCATCGGCGCGCCGGATGGATGTGCCAACTACAT
CCTGCCGCAGGTCTGTGCCGCGATTTCCAAAGACAACCCGGATCTTGATATTCAGGTTGTCGCCTTGCCGCGTGTGATCA
ACCTGTCGCGGCGCGAGGCGGATATGGCCGTCACCGTCAGCGCGCCAACTGCGGGCAAGCTGCTGGTGCAAAAGATCACC
GATTATCACCTGCATCTGGCGGCCACCCGCCACTATCTGCGCGACAATCACCCGATCGAAAAGCTCGAGCACCTGCGCGA
CCATCGCATGATCGGCTACATTCCGGACATGATCTTTGATCGCGAGTTGGATTACCTCAATGATCTGGGCATCGAGCGCG
TGTCGCTGGCGTCCAATTCGGTCTCTGTCCAGATCAAGATGCTTGCCGAAGGCAGCGCGCTTGGCGTGGTGCATGATTTT
TCACTGCCGAGCCACCGGACCCTGCGCAAAGTGCTGAAGGAAGAGTTCAGCCTGACCCGCAGTTTTTACCTTGTCCGCCA
TCAGGGCGACCAGCGCAGCGACCGGCTTAATCGCTTTGCAGAGGCGCTCTCGGCGGGGATACGCGCAGAGGTTGAGCGAT
TGGAAGGCTTGACTTGA

Upstream 100 bases:

>100_bases
GTAAAAGAGGAAAGGCTTCAAATAGGTTTTGCATTTACGCAAATGGTTAAGGTAGGTTAACCATGAGCAGAATGCGAAGA
AGGCTGGAGGATCCCGTCAG

Downstream 100 bases:

>100_bases
TGTGATCTTGCGGCAAACCTTGAGGGAGTGAAAGAAAATTTCAAGGGTGCGCAAAATGCTCGTTAAGTCGATCCTTAAGT
CCAAAGATATCGCCGAAGTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MEPQWDDMKVFLAVARESSLSGAGRVLKMDPATVGRRVARFEAALKTSLFVKSPQGYALSAAGDRLLGHAEAAELAMRAG
EEALTGPSDTLSGQIRIGAPDGCANYILPQVCAAISKDNPDLDIQVVALPRVINLSRREADMAVTVSAPTAGKLLVQKIT
DYHLHLAATRHYLRDNHPIEKLEHLRDHRMIGYIPDMIFDRELDYLNDLGIERVSLASNSVSVQIKMLAEGSALGVVHDF
SLPSHRTLRKVLKEEFSLTRSFYLVRHQGDQRSDRLNRFAEALSAGIRAEVERLEGLT

Sequences:

>Translated_298_residues
MEPQWDDMKVFLAVARESSLSGAGRVLKMDPATVGRRVARFEAALKTSLFVKSPQGYALSAAGDRLLGHAEAAELAMRAG
EEALTGPSDTLSGQIRIGAPDGCANYILPQVCAAISKDNPDLDIQVVALPRVINLSRREADMAVTVSAPTAGKLLVQKIT
DYHLHLAATRHYLRDNHPIEKLEHLRDHRMIGYIPDMIFDRELDYLNDLGIERVSLASNSVSVQIKMLAEGSALGVVHDF
SLPSHRTLRKVLKEEFSLTRSFYLVRHQGDQRSDRLNRFAEALSAGIRAEVERLEGLT
>Mature_298_residues
MEPQWDDMKVFLAVARESSLSGAGRVLKMDPATVGRRVARFEAALKTSLFVKSPQGYALSAAGDRLLGHAEAAELAMRAG
EEALTGPSDTLSGQIRIGAPDGCANYILPQVCAAISKDNPDLDIQVVALPRVINLSRREADMAVTVSAPTAGKLLVQKIT
DYHLHLAATRHYLRDNHPIEKLEHLRDHRMIGYIPDMIFDRELDYLNDLGIERVSLASNSVSVQIKMLAEGSALGVVHDF
SLPSHRTLRKVLKEEFSLTRSFYLVRHQGDQRSDRLNRFAEALSAGIRAEVERLEGLT

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=238, Percent_Identity=22.6890756302521, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789440, Length=297, Percent_Identity=23.5690235690236, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1786401, Length=249, Percent_Identity=21.285140562249, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32876; Mature: 32876

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPQWDDMKVFLAVARESSLSGAGRVLKMDPATVGRRVARFEAALKTSLFVKSPQGYALS
CCCCHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHEEECCCCCEEE
AAGDRLLGHAEAAELAMRAGEEALTGPSDTLSGQIRIGAPDGCANYILPQVCAAISKDNP
CCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
DLDIQVVALPRVINLSRREADMAVTVSAPTAGKLLVQKITDYHLHLAATRHYLRDNHPIE
CCEEEEEEECHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KLEHLRDHRMIGYIPDMIFDRELDYLNDLGIERVSLASNSVSVQIKMLAEGSALGVVHDF
HHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCEEEECCCCEEEEEEEEECCCEEEEEEEC
SLPSHRTLRKVLKEEFSLTRSFYLVRHQGDQRSDRLNRFAEALSAGIRAEVERLEGLT
CCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEPQWDDMKVFLAVARESSLSGAGRVLKMDPATVGRRVARFEAALKTSLFVKSPQGYALS
CCCCHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHEEECCCCCEEE
AAGDRLLGHAEAAELAMRAGEEALTGPSDTLSGQIRIGAPDGCANYILPQVCAAISKDNP
CCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
DLDIQVVALPRVINLSRREADMAVTVSAPTAGKLLVQKITDYHLHLAATRHYLRDNHPIE
CCEEEEEEECHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KLEHLRDHRMIGYIPDMIFDRELDYLNDLGIERVSLASNSVSVQIKMLAEGSALGVVHDF
HHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCEEEECCCCEEEEEEEEECCCEEEEEEEC
SLPSHRTLRKVLKEEFSLTRSFYLVRHQGDQRSDRLNRFAEALSAGIRAEVERLEGLT
CCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]