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The map label for this gene is arcB [H]

Identifier: 99080803

GI number: 99080803

Start: 1027874

End: 1030345

Strand: Direct

Name: arcB [H]

Synonym: TM1040_0962

Alternate gene names: 99080803

Gene position: 1027874-1030345 (Clockwise)

Preceding gene: 99080802

Following gene: 99080804

Centisome position: 32.11

GC content: 59.55

Gene sequence:

>2472_bases
GTGCGACAGAAGATACCGATTATGCATCGCTGGGTTATTTCCGCAGCCGCCGTGGTTCTTATACTGCTGGCGGCTCAGGC
CTATCGTTTGGGAAGCGATGTTCAGTCGCGGATCGAAGCTCTGTCGAGCGCCGCAACCGACAACCTTCAGTGGACTTTGT
CACAGGCCGAGGTCGACTATCTGAAATATCGCTCCGCCGCGATGGTGGTGGAAGATCGCAGCGATCTTCCACGCCTTCGA
CGCCAGTTCGATATCTATTACAGCCGCATCGCGACTTTTCGAGAAAGTGCGCTTTATTCGGAAGTGCGCGCCACCCCTGA
AGGCAGTGAAACGCTCGGGCGGCTGCAACAGGGGTTGCAGAGACAAGCGGCACTTATTGACGCGTCTGACGATGTTCTGC
TCTCCGAGAAAGAGAATTTGCTGCAGCTGATTGCCGTCGATGGCAATGATGTGCGCGATCTCGCGCTTTTTGGCGTGGCG
CTACAGGCCGAGACGGCGGGCGCGGAGCGGGTTTTGCTGCACACATTGTTCACCCGTCTTGCGATTGTGGTTCTGGCGCT
TCTTGGGACGCTTGCGCTCACTGCTCTGGTGATCCTGCGCCTGTTCCGGCGGGGGCAGCGGCTTTCGATGCTGCAGGCGC
AGGAGGCCGCCCGCACAGAGGCGATGGTCACATCTTCCCTCGATGCGATCCTAATGGCGGATGCGGAGGGTCGCATCACC
GCCATCAACGGCGCCGCTGAGGAGATTTTTGGCTACAGCGAAGAGGAGGCGATCGGGATGAATTTCGACTCGCTGATCCT
GCAATCTCCCGAGGGTGCCGGGGCTGGCGATCTTGACGATTTTCTGAACGAGAACGATGGCCGGTTCCAGATGACCGCCC
AGAGGAAGACCGGCGATGTGATCCCGGTCGAAGTCTCATTGACGGTGAGCAAATCTGATGGAAATCAGGTACTTGTCAGC
TATGTGCGCGACATTTCCCATCGCCTGCAAGCCGAGGAAGAACTGCGCCGGGCACGCGATGACGCGCTTGCAGGAGAACA
GGCCAAAGATCGCCTTCTGACGGTGATGAGCCACGAGATGCGCACGCCGCTCACGGGTATCCTTGGCTCGCTTGATGTGC
TCGAGGGGCTGACGCCGAGCGCAGAGCAACAGCGATACCTGCAGGCCATGCGGGTGTCGGGCGAGCTGCTGTTGCATCAC
GTCAATGACGTCTTGCAGCTTTCGCGACTCGAATCCGGCGCCGAGGCGGACGCGCCCATTCGCTTTGATCTCGACGAACT
TGTGCGTGGCATCGGGGAGAGCCAGCAGGCCAATGCGGCCCGCAACAACAATGACTTAAGTGTATTCTGCAGCCTTGGCG
CCGAAACCGGGGTCGAGGGGCATTGTCGTTATGTGCAGCAGGTCCTGCTCAATCTCATCGGAAACGCGCTGAAGTTCACC
CAGGATGGCGCTGTTTCGGTGGATGTGATGCGTACCGAAGGCGACCTGGTGGAATTCAGTGTCGCAGATACCGGGAAAGG
CATCGCAGCCGAGGATCTGGAACGCATCTTCGACGAATTCACCATGGTAGACCCCAATTACAATCGCGGCTGCGAGGGTA
CCGGTCTGGGGCTGGCGATTTCACGCCGGTTGGCCCGGTTGATGGGGGGAGAGATCACCTGCGAAAGCGAACCGGGCGAG
GGCAGCCTGTTTAGTTTCACCATTCCCCTGCCGCCCGTCGCTCTGGAACAGGGCAAGCCGGTGTTTGCCGCCGATGCTCC
AACCCGCCAGCAGCGCCTTCTAGTGATCGAAGATAACGATATCAACCGGTTGCTTCTCGAGACCATGTTGAACGACATGG
GACATGAGGTGGTTTCCGTCAACGGCGGCGCGCGCGCTATCGAGGAAATTCGCACCCACCGCTTTGATCTGATCATCTCG
GACATCAGCATGCCGGATATCGACGGTATGGAAGTCTTGCGCCGCGTCCGTGCAGAGCAACTCGCAAATGATACCGACAT
TGTTGCCCTGACCGCTCATGCCGCGCGTGACGATCACGAACGCATCCTCGCCGCTGGCTTTGCAGAGGTGTTGACCAAGC
CCATAGATCGCGCGGCGCTGGCCGAGATGGTGCTGCGGCGGTCCGCGGCCGATGCTGCGGCGCCCATTCCTGCGCAATAT
CCGGGAGAGTCTGACATTTCTCAATTCGTCGCGGCCGTGGGGCCGGAGAAAGCGCGCCATTTTCTCGCAGAGTTTCGCGA
TGATGTCCGCGCTTTGCGTGAGGCCCTGACCCAGAGCGTTGAATTGACCGATCAGCACCGTAAGGAAGCTCATCGCCTCG
CAGGGTCTGCCGCGGTGCTGGGGCTTGCGACGCTGCGCAGCTCGATGCTCGAGATTGAGCAGGCGAATACCAATGCTTTG
CCCGAGTTGGCACCTCTGCAAGATGCCTGGGGCAACGCTGAAAAAGTCCTCGCGATCCATGTGGCATCCTGA

Upstream 100 bases:

>100_bases
TGAAGAGGTCTACTCTCGCAGTATCTGGCAGTTGAACAGGATAACGGTGAAGTAACGCGCCTTGCGGCGGGCCCATACTG
CAGGAGGACTCCAGCGCTTG

Downstream 100 bases:

>100_bases
CCGGGGCTTCACCAAAGTGCACGTCCCCCCTCAGGTTGGCCAAGGGTATCACGGCAAGCTGCGCCGCTGTCCGGAGCTGC
GCCGCTGTCCCGAAAAGGCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 823; Mature: 823

Protein sequence:

>823_residues
MRQKIPIMHRWVISAAAVVLILLAAQAYRLGSDVQSRIEALSSAATDNLQWTLSQAEVDYLKYRSAAMVVEDRSDLPRLR
RQFDIYYSRIATFRESALYSEVRATPEGSETLGRLQQGLQRQAALIDASDDVLLSEKENLLQLIAVDGNDVRDLALFGVA
LQAETAGAERVLLHTLFTRLAIVVLALLGTLALTALVILRLFRRGQRLSMLQAQEAARTEAMVTSSLDAILMADAEGRIT
AINGAAEEIFGYSEEEAIGMNFDSLILQSPEGAGAGDLDDFLNENDGRFQMTAQRKTGDVIPVEVSLTVSKSDGNQVLVS
YVRDISHRLQAEEELRRARDDALAGEQAKDRLLTVMSHEMRTPLTGILGSLDVLEGLTPSAEQQRYLQAMRVSGELLLHH
VNDVLQLSRLESGAEADAPIRFDLDELVRGIGESQQANAARNNNDLSVFCSLGAETGVEGHCRYVQQVLLNLIGNALKFT
QDGAVSVDVMRTEGDLVEFSVADTGKGIAAEDLERIFDEFTMVDPNYNRGCEGTGLGLAISRRLARLMGGEITCESEPGE
GSLFSFTIPLPPVALEQGKPVFAADAPTRQQRLLVIEDNDINRLLLETMLNDMGHEVVSVNGGARAIEEIRTHRFDLIIS
DISMPDIDGMEVLRRVRAEQLANDTDIVALTAHAARDDHERILAAGFAEVLTKPIDRAALAEMVLRRSAADAAAPIPAQY
PGESDISQFVAAVGPEKARHFLAEFRDDVRALREALTQSVELTDQHRKEAHRLAGSAAVLGLATLRSSMLEIEQANTNAL
PELAPLQDAWGNAEKVLAIHVAS

Sequences:

>Translated_823_residues
MRQKIPIMHRWVISAAAVVLILLAAQAYRLGSDVQSRIEALSSAATDNLQWTLSQAEVDYLKYRSAAMVVEDRSDLPRLR
RQFDIYYSRIATFRESALYSEVRATPEGSETLGRLQQGLQRQAALIDASDDVLLSEKENLLQLIAVDGNDVRDLALFGVA
LQAETAGAERVLLHTLFTRLAIVVLALLGTLALTALVILRLFRRGQRLSMLQAQEAARTEAMVTSSLDAILMADAEGRIT
AINGAAEEIFGYSEEEAIGMNFDSLILQSPEGAGAGDLDDFLNENDGRFQMTAQRKTGDVIPVEVSLTVSKSDGNQVLVS
YVRDISHRLQAEEELRRARDDALAGEQAKDRLLTVMSHEMRTPLTGILGSLDVLEGLTPSAEQQRYLQAMRVSGELLLHH
VNDVLQLSRLESGAEADAPIRFDLDELVRGIGESQQANAARNNNDLSVFCSLGAETGVEGHCRYVQQVLLNLIGNALKFT
QDGAVSVDVMRTEGDLVEFSVADTGKGIAAEDLERIFDEFTMVDPNYNRGCEGTGLGLAISRRLARLMGGEITCESEPGE
GSLFSFTIPLPPVALEQGKPVFAADAPTRQQRLLVIEDNDINRLLLETMLNDMGHEVVSVNGGARAIEEIRTHRFDLIIS
DISMPDIDGMEVLRRVRAEQLANDTDIVALTAHAARDDHERILAAGFAEVLTKPIDRAALAEMVLRRSAADAAAPIPAQY
PGESDISQFVAAVGPEKARHFLAEFRDDVRALREALTQSVELTDQHRKEAHRLAGSAAVLGLATLRSSMLEIEQANTNAL
PELAPLQDAWGNAEKVLAIHVAS
>Mature_823_residues
MRQKIPIMHRWVISAAAVVLILLAAQAYRLGSDVQSRIEALSSAATDNLQWTLSQAEVDYLKYRSAAMVVEDRSDLPRLR
RQFDIYYSRIATFRESALYSEVRATPEGSETLGRLQQGLQRQAALIDASDDVLLSEKENLLQLIAVDGNDVRDLALFGVA
LQAETAGAERVLLHTLFTRLAIVVLALLGTLALTALVILRLFRRGQRLSMLQAQEAARTEAMVTSSLDAILMADAEGRIT
AINGAAEEIFGYSEEEAIGMNFDSLILQSPEGAGAGDLDDFLNENDGRFQMTAQRKTGDVIPVEVSLTVSKSDGNQVLVS
YVRDISHRLQAEEELRRARDDALAGEQAKDRLLTVMSHEMRTPLTGILGSLDVLEGLTPSAEQQRYLQAMRVSGELLLHH
VNDVLQLSRLESGAEADAPIRFDLDELVRGIGESQQANAARNNNDLSVFCSLGAETGVEGHCRYVQQVLLNLIGNALKFT
QDGAVSVDVMRTEGDLVEFSVADTGKGIAAEDLERIFDEFTMVDPNYNRGCEGTGLGLAISRRLARLMGGEITCESEPGE
GSLFSFTIPLPPVALEQGKPVFAADAPTRQQRLLVIEDNDINRLLLETMLNDMGHEVVSVNGGARAIEEIRTHRFDLIIS
DISMPDIDGMEVLRRVRAEQLANDTDIVALTAHAARDDHERILAAGFAEVLTKPIDRAALAEMVLRRSAADAAAPIPAQY
PGESDISQFVAAVGPEKARHFLAEFRDDVRALREALTQSVELTDQHRKEAHRLAGSAAVLGLATLRSSMLEIEQANTNAL
PELAPLQDAWGNAEKVLAIHVAS

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=651, Percent_Identity=28.8786482334869, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1788713, Length=669, Percent_Identity=26.1584454409567, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI87081816, Length=486, Percent_Identity=30.8641975308642, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI145693157, Length=285, Percent_Identity=35.0877192982456, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1789149, Length=455, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786600, Length=344, Percent_Identity=27.906976744186, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=380, Percent_Identity=25.5263157894737, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=29.4871794871795, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=30.2788844621514, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.8537549407115, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=27.4336283185841, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89849; Mature: 89849

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQKIPIMHRWVISAAAVVLILLAAQAYRLGSDVQSRIEALSSAATDNLQWTLSQAEVDY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
LKYRSAAMVVEDRSDLPRLRRQFDIYYSRIATFRESALYSEVRATPEGSETLGRLQQGLQ
HHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RQAALIDASDDVLLSEKENLLQLIAVDGNDVRDLALFGVALQAETAGAERVLLHTLFTRL
HHHHHCCCCCCEEHHCHHCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AIVVLALLGTLALTALVILRLFRRGQRLSMLQAQEAARTEAMVTSSLDAILMADAEGRIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEE
AINGAAEEIFGYSEEEAIGMNFDSLILQSPEGAGAGDLDDFLNENDGRFQMTAQRKTGDV
EECCCHHHHCCCCCCCCCCCCHHHHHEECCCCCCCCCHHHHHCCCCCEEEEEEECCCCCE
IPVEVSLTVSKSDGNQVLVSYVRDISHRLQAEEELRRARDDALAGEQAKDRLLTVMSHEM
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RTPLTGILGSLDVLEGLTPSAEQQRYLQAMRVSGELLLHHVNDVLQLSRLESGAEADAPI
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
RFDLDELVRGIGESQQANAARNNNDLSVFCSLGAETGVEGHCRYVQQVLLNLIGNALKFT
EECHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QDGAVSVDVMRTEGDLVEFSVADTGKGIAAEDLERIFDEFTMVDPNYNRGCEGTGLGLAI
CCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCHHHH
SRRLARLMGGEITCESEPGEGSLFSFTIPLPPVALEQGKPVFAADAPTRQQRLLVIEDND
HHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEEECCC
INRLLLETMLNDMGHEVVSVNGGARAIEEIRTHRFDLIISDISMPDIDGMEVLRRVRAEQ
HHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHH
LANDTDIVALTAHAARDDHERILAAGFAEVLTKPIDRAALAEMVLRRSAADAAAPIPAQY
HCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PGESDISQFVAAVGPEKARHFLAEFRDDVRALREALTQSVELTDQHRKEAHRLAGSAAVL
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
GLATLRSSMLEIEQANTNALPELAPLQDAWGNAEKVLAIHVAS
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEEEEEECC
>Mature Secondary Structure
MRQKIPIMHRWVISAAAVVLILLAAQAYRLGSDVQSRIEALSSAATDNLQWTLSQAEVDY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
LKYRSAAMVVEDRSDLPRLRRQFDIYYSRIATFRESALYSEVRATPEGSETLGRLQQGLQ
HHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RQAALIDASDDVLLSEKENLLQLIAVDGNDVRDLALFGVALQAETAGAERVLLHTLFTRL
HHHHHCCCCCCEEHHCHHCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AIVVLALLGTLALTALVILRLFRRGQRLSMLQAQEAARTEAMVTSSLDAILMADAEGRIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEE
AINGAAEEIFGYSEEEAIGMNFDSLILQSPEGAGAGDLDDFLNENDGRFQMTAQRKTGDV
EECCCHHHHCCCCCCCCCCCCHHHHHEECCCCCCCCCHHHHHCCCCCEEEEEEECCCCCE
IPVEVSLTVSKSDGNQVLVSYVRDISHRLQAEEELRRARDDALAGEQAKDRLLTVMSHEM
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RTPLTGILGSLDVLEGLTPSAEQQRYLQAMRVSGELLLHHVNDVLQLSRLESGAEADAPI
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
RFDLDELVRGIGESQQANAARNNNDLSVFCSLGAETGVEGHCRYVQQVLLNLIGNALKFT
EECHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCC
QDGAVSVDVMRTEGDLVEFSVADTGKGIAAEDLERIFDEFTMVDPNYNRGCEGTGLGLAI
CCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCHHHH
SRRLARLMGGEITCESEPGEGSLFSFTIPLPPVALEQGKPVFAADAPTRQQRLLVIEDND
HHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCEEEEEECCC
INRLLLETMLNDMGHEVVSVNGGARAIEEIRTHRFDLIISDISMPDIDGMEVLRRVRAEQ
HHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHH
LANDTDIVALTAHAARDDHERILAAGFAEVLTKPIDRAALAEMVLRRSAADAAAPIPAQY
HCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PGESDISQFVAAVGPEKARHFLAEFRDDVRALREALTQSVELTDQHRKEAHRLAGSAAVL
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
GLATLRSSMLEIEQANTNALPELAPLQDAWGNAEKVLAIHVAS
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]