Click here to switch to the map view.

The map label for this gene is ykuT [H]

Identifier: 94985933

GI number: 94985933

Start: 1946288

End: 1947472

Strand: Reverse

Name: ykuT [H]

Synonym: Dgeo_1833

Alternate gene names: 94985933

Gene position: 1947472-1946288 (Counterclockwise)

Preceding gene: 94985934

Following gene: 94985931

Centisome position: 78.93

GC content: 62.78

Gene sequence:

>1185_bases
ATGCTGGACGAACTGCTGATTCAACTGCAAAAGCCGCAGGTCTGGCTGGGTTTGGCGCTTACGCTGCTGGTTGCCTACGC
GCTGTACCGCTTTGGGCGCCTGCTCCTGCGTTCGCTGGAAAGTTATGTGCGGGGGCCGCTGGTGATTGCCCTGAAGTGGC
TGTGGTTGCTGGTGGTTACCGTGGCCTGGTTGGCGGTCGCGACGCACGTCGTGTACCTGCCGGGCGTGCCGGTGTTGTTC
GAGCTGGGGCAGGACATTTTCAATGGCTTCCGCAACAGTGCGGGGCAGGTGCTGGTGATCCTGGCGCTGGCGCTGATCGC
CTGGAACCTGATCGGCAGCCTGAGCGCGCGCATTGTGGCTGAGGAGGAATTCAACCGCCGGACGGTGCGGGTCCAGACCC
TGAAGGGCGTGGTCGAGAGCACGCTGAAAGCGGTGGTGGTGCTGATCAGCCTGATTGCTGGCCTGCAGGCACTCGGTGTG
AATGCCTCTAGCCTGCTGGCGGGCGTGTCGGTGCTGGGCTTGGCGGTCGGCTTTGGCGCCCAGAGCCTGATCAAGGATGT
GTTCACCGGCTTTTTTATCCTGCTGGAAGACCAGTACGGCGTCGGGGACGTCATCACGGTGAATACCGGACAGCTCAGCG
GCAATGTGGAACGCCTGAACCTGCGCGTGACTGTGCTGCGGGCTTTGGACGGCACGGTCCACATCATCCCCAATGGCCAG
ATTCAGACCGTCAGTGTCAGCAGCAAGGACTGGTCGCGGGTGGTGGCGACGGTGGACGTGACCTACGCCGCCAATATCAA
TGACGCCCTGCGCGTGCTGGAGACGGTCAGTCGGGAGATCTACGCTGACCCCGAGTGGGCCCGCTTTTTCCTCGAAGAAC
CCGAGATCCAGGGGGTGACCCAGCTGAACCCCGATGGTGTGACGTTGCGCGCGCTCTTCAAGGTGCAGCCTAAAAGCCAG
TATGCCATCGGGCGCGAATTCAACCGCCGCATCAAAATTGCGATGGATCAGGCGGGCATTCAGATCCCTTCCCCACAGCG
CACCGTCACCCTGGGCAATGCTCCCATTGCCATTCGGCTGACGCGGGAAGGGCCGGAAGGCCGCGATCCGCGCAGTGGAC
AGGAACGCACCCACCCACCGGTGGAGCCCACCTTCACCCGCGACCCGGAGGAAGAGGAAGTTTAG

Upstream 100 bases:

>100_bases
CCTCGCGTGCCTATGAGGCGAAGCTGATTGAGCGGTTGGAAGCGGCGCTGACGCCCCAGGACGGCTAACTTCCCTCATGT
CCTCATGAGAGGCTGAGGGA

Downstream 100 bases:

>100_bases
CATCAGGCCGGTAGGGGAGCGGTGGGCGCTGGGCCGTCCGCTGCCGCCCCAGATCCCTCCTCTAGCGTTCCTCCGGCGAG
CAGGGTGGAGAATTCCTCGC

Product: MscS mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLDELLIQLQKPQVWLGLALTLLVAYALYRFGRLLLRSLESYVRGPLVIALKWLWLLVVTVAWLAVATHVVYLPGVPVLF
ELGQDIFNGFRNSAGQVLVILALALIAWNLIGSLSARIVAEEEFNRRTVRVQTLKGVVESTLKAVVVLISLIAGLQALGV
NASSLLAGVSVLGLAVGFGAQSLIKDVFTGFFILLEDQYGVGDVITVNTGQLSGNVERLNLRVTVLRALDGTVHIIPNGQ
IQTVSVSSKDWSRVVATVDVTYAANINDALRVLETVSREIYADPEWARFFLEEPEIQGVTQLNPDGVTLRALFKVQPKSQ
YAIGREFNRRIKIAMDQAGIQIPSPQRTVTLGNAPIAIRLTREGPEGRDPRSGQERTHPPVEPTFTRDPEEEEV

Sequences:

>Translated_394_residues
MLDELLIQLQKPQVWLGLALTLLVAYALYRFGRLLLRSLESYVRGPLVIALKWLWLLVVTVAWLAVATHVVYLPGVPVLF
ELGQDIFNGFRNSAGQVLVILALALIAWNLIGSLSARIVAEEEFNRRTVRVQTLKGVVESTLKAVVVLISLIAGLQALGV
NASSLLAGVSVLGLAVGFGAQSLIKDVFTGFFILLEDQYGVGDVITVNTGQLSGNVERLNLRVTVLRALDGTVHIIPNGQ
IQTVSVSSKDWSRVVATVDVTYAANINDALRVLETVSREIYADPEWARFFLEEPEIQGVTQLNPDGVTLRALFKVQPKSQ
YAIGREFNRRIKIAMDQAGIQIPSPQRTVTLGNAPIAIRLTREGPEGRDPRSGQERTHPPVEPTFTRDPEEEEV
>Mature_394_residues
MLDELLIQLQKPQVWLGLALTLLVAYALYRFGRLLLRSLESYVRGPLVIALKWLWLLVVTVAWLAVATHVVYLPGVPVLF
ELGQDIFNGFRNSAGQVLVILALALIAWNLIGSLSARIVAEEEFNRRTVRVQTLKGVVESTLKAVVVLISLIAGLQALGV
NASSLLAGVSVLGLAVGFGAQSLIKDVFTGFFILLEDQYGVGDVITVNTGQLSGNVERLNLRVTVLRALDGTVHIIPNGQ
IQTVSVSSKDWSRVVATVDVTYAANINDALRVLETVSREIYADPEWARFFLEEPEIQGVTQLNPDGVTLRALFKVQPKSQ
YAIGREFNRRIKIAMDQAGIQIPSPQRTVTLGNAPIAIRLTREGPEGRDPRSGQERTHPPVEPTFTRDPEEEEV

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=269, Percent_Identity=30.8550185873606, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI2367355, Length=142, Percent_Identity=30.2816901408451, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 43286; Mature: 43286

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDELLIQLQKPQVWLGLALTLLVAYALYRFGRLLLRSLESYVRGPLVIALKWLWLLVVT
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VAWLAVATHVVYLPGVPVLFELGQDIFNGFRNSAGQVLVILALALIAWNLIGSLSARIVA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
EEEFNRRTVRVQTLKGVVESTLKAVVVLISLIAGLQALGVNASSLLAGVSVLGLAVGFGA
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCH
QSLIKDVFTGFFILLEDQYGVGDVITVNTGQLSGNVERLNLRVTVLRALDGTVHIIPNGQ
HHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCEEEEEEEEEEEEECCCEEEEEECCE
IQTVSVSSKDWSRVVATVDVTYAANINDALRVLETVSREIYADPEWARFFLEEPEIQGVT
EEEEEECCCCHHEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCE
QLNPDGVTLRALFKVQPKSQYAIGREFNRRIKIAMDQAGIQIPSPQRTVTLGNAPIAIRL
EECCCCEEEEEEEEECCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCEEEEE
TREGPEGRDPRSGQERTHPPVEPTFTRDPEEEEV
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLDELLIQLQKPQVWLGLALTLLVAYALYRFGRLLLRSLESYVRGPLVIALKWLWLLVVT
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VAWLAVATHVVYLPGVPVLFELGQDIFNGFRNSAGQVLVILALALIAWNLIGSLSARIVA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEE
EEEFNRRTVRVQTLKGVVESTLKAVVVLISLIAGLQALGVNASSLLAGVSVLGLAVGFGA
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCH
QSLIKDVFTGFFILLEDQYGVGDVITVNTGQLSGNVERLNLRVTVLRALDGTVHIIPNGQ
HHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCEEEEEEEEEEEEECCCEEEEEECCE
IQTVSVSSKDWSRVVATVDVTYAANINDALRVLETVSREIYADPEWARFFLEEPEIQGVT
EEEEEECCCCHHEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCE
QLNPDGVTLRALFKVQPKSQYAIGREFNRRIKIAMDQAGIQIPSPQRTVTLGNAPIAIRL
EECCCCEEEEEEEEECCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCEEEEE
TREGPEGRDPRSGQERTHPPVEPTFTRDPEEEEV
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]