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The map label for this gene is greA [H]

Identifier: 94985913

GI number: 94985913

Start: 1929484

End: 1929960

Strand: Reverse

Name: greA [H]

Synonym: Dgeo_1813

Alternate gene names: 94985913

Gene position: 1929960-1929484 (Counterclockwise)

Preceding gene: 94985915

Following gene: 94985906

Centisome position: 78.22

GC content: 63.31

Gene sequence:

>477_bases
ATGGCAGAAGAAATTCCGATGACGGCAGAAGGTTACCGGCGCCTTCAGGAAACCCTGGAGAAGGAACGGCAACGCCTGGA
AGACGCCACCACCAGCATGGCCGCCACCCTAGACGACGCGATGGACCTTGAAGACCGCAGCTTTCAGGCCGCCCAGTATG
ATCTACCGACAATGGAGGCGCGCATCCTGGAACTGGAAGATGTTCTGGCGCGCGCCGTGATTGTGGAAGAACCTCAGGCC
CGGGACGGAGGGGTGGCCCTGGGCTCGGTGGTGGTGCTGCGTGACGAGCAGCATGACCGCGAGTTGCGTGTCCAGCTTGT
CAGTGCTGTGGAAGTGGACGCCCTGGCCGAAGGTGCTACCCAAGTCAGCGAGGACAGCCCAGTCGGCAAGGCCCTGCTGG
GTCGGCGGGCTGGAGAGTCCTTCGAGGTGGACCTGGGATCGTCCCGGGCGCGCTACACCGTGAAGAGCATCGGCTAA

Upstream 100 bases:

>100_bases
CTAAAGGAATCTTGGGAAAGCTGGGCCGGGGTGTCGGACCTTGAGTTTCCTATCATGGAGGTGCCCAGCTGGCTTTCTAG
AGTGAACGCCGAGGTGTGGC

Downstream 100 bases:

>100_bases
GTGTGCAGTGGGCGTGGTGACCGGCTGCTTTGGCCACCGCTTGCCGCTTCCGCTGCCTTCTCCCTCAGCTCTCCTACACG
TCCCGCCGTTCAAACGCATA

Product: GreA/GreB family elongation factor

Products: NA

Alternate protein names: Transcript cleavage factor greA [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAEEIPMTAEGYRRLQETLEKERQRLEDATTSMAATLDDAMDLEDRSFQAAQYDLPTMEARILELEDVLARAVIVEEPQA
RDGGVALGSVVVLRDEQHDRELRVQLVSAVEVDALAEGATQVSEDSPVGKALLGRRAGESFEVDLGSSRARYTVKSIG

Sequences:

>Translated_158_residues
MAEEIPMTAEGYRRLQETLEKERQRLEDATTSMAATLDDAMDLEDRSFQAAQYDLPTMEARILELEDVLARAVIVEEPQA
RDGGVALGSVVVLRDEQHDRELRVQLVSAVEVDALAEGATQVSEDSPVGKALLGRRAGESFEVDLGSSRARYTVKSIG
>Mature_157_residues
AEEIPMTAEGYRRLQETLEKERQRLEDATTSMAATLDDAMDLEDRSFQAAQYDLPTMEARILELEDVLARAVIVEEPQAR
DGGVALGSVVVLRDEQHDRELRVQLVSAVEVDALAEGATQVSEDSPVGKALLGRRAGESFEVDLGSSRARYTVKSIG

Specific function: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary

COG id: COG0782

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the greA/greB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001437
- InterPro:   IPR022691 [H]

Pfam domain/function: PF01272 GreA_GreB; PF03449 GreA_GreB_N [H]

EC number: NA

Molecular weight: Translated: 17350; Mature: 17218

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00830 GREAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEIPMTAEGYRRLQETLEKERQRLEDATTSMAATLDDAMDLEDRSFQAAQYDLPTMEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHH
RILELEDVLARAVIVEEPQARDGGVALGSVVVLRDEQHDRELRVQLVSAVEVDALAEGAT
HHHHHHHHHHHHHHHCCCCCCCCCEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHH
QVSEDSPVGKALLGRRAGESFEVDLGSSRARYTVKSIG
HCCCCCCHHHHHHHHCCCCCEEEECCCCCCEEEEECCC
>Mature Secondary Structure 
AEEIPMTAEGYRRLQETLEKERQRLEDATTSMAATLDDAMDLEDRSFQAAQYDLPTMEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHH
RILELEDVLARAVIVEEPQARDGGVALGSVVVLRDEQHDRELRVQLVSAVEVDALAEGAT
HHHHHHHHHHHHHHHCCCCCCCCCEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHH
QVSEDSPVGKALLGRRAGESFEVDLGSSRARYTVKSIG
HCCCCCCHHHHHHHHCCCCCEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA