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The map label for this gene is 94985881

Identifier: 94985881

GI number: 94985881

Start: 1896811

End: 1897455

Strand: Reverse

Name: 94985881

Synonym: Dgeo_1781

Alternate gene names: NA

Gene position: 1897455-1896811 (Counterclockwise)

Preceding gene: 94985882

Following gene: 94985870

Centisome position: 76.91

GC content: 68.53

Gene sequence:

>645_bases
ATGAGCCGCCGTTCTCCCTTTCCGCCGCAGCCCCCGCGCAGGCGTTCCCGTTCCCCGGTGGGGCGGGCGGCGCTGCTCGC
CCTGCTGCTGGTAGGGGGCGAATGGGCACAGGAATTCACCGATCAGCTCGTATTCGGCGGGGCACTCGACCGGTACGGGA
TCGTGCCGCGTGATCCCGGCAGCCTCTCCCACATCCTGACGGCGCCCTTCCTGCATGTGGGATTTCCCCATCTGATCGCC
AACACGGCGCCCCTGGCGGTGCTGGCCTTCATGAGTGCCCTGCGCGGCGCCGCGCGTTTTGTGCTGGCGACACTGGTGAT
TGTGGTGGTGGGTGGCGGGCTGGTGTGGCTGCTGGGACGGGGCGGGAGCGACCACCTAGGGGCCAGCGAACTGGTGTTTG
GCTATTTCGCCTACCTGGTGGGCGTGGGCTGGTGGGAAAGAACACCCGCCGCCGTCGCGGTGGCCCTCGTCACCCTCTTG
CTGTATGGCGGGATACTGTGGGGCGTGCTGCCCACCCATCCCATCATCTCCTGGGAAGCGCACCTCTTCGGCTTCGTGGC
GGGTCTGATCGCGGCGGCGCTGCTGCACCGGCGGCGGCCGCGTGCTGGTCGGGTCAGCCCCTATTCCCCGCGTTCGAGAT
TCTGA

Upstream 100 bases:

>100_bases
AAGGGGGCGCTCCGCGGGCGCGTCAGCGGGTAAAGAGTGGGCAGAAGGCCAGTGGGAAGCGTCCCGTTGGCCTTCTCCCT
TTTGGGGCAGACTAGGCGCC

Downstream 100 bases:

>100_bases
AGAGCAGGGCGACGCGGCCCGCTGCATGCTGCCGCCTCACAACGTCACCAGTCCCCCTGGCGTCACCAGCAGCGCGGACA
ATTCCACCTGCGGCGCTTCA

Product: rhomboid-like protein protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSRRSPFPPQPPRRRSRSPVGRAALLALLLVGGEWAQEFTDQLVFGGALDRYGIVPRDPGSLSHILTAPFLHVGFPHLIA
NTAPLAVLAFMSALRGAARFVLATLVIVVVGGGLVWLLGRGGSDHLGASELVFGYFAYLVGVGWWERTPAAVAVALVTLL
LYGGILWGVLPTHPIISWEAHLFGFVAGLIAAALLHRRRPRAGRVSPYSPRSRF

Sequences:

>Translated_214_residues
MSRRSPFPPQPPRRRSRSPVGRAALLALLLVGGEWAQEFTDQLVFGGALDRYGIVPRDPGSLSHILTAPFLHVGFPHLIA
NTAPLAVLAFMSALRGAARFVLATLVIVVVGGGLVWLLGRGGSDHLGASELVFGYFAYLVGVGWWERTPAAVAVALVTLL
LYGGILWGVLPTHPIISWEAHLFGFVAGLIAAALLHRRRPRAGRVSPYSPRSRF
>Mature_213_residues
SRRSPFPPQPPRRRSRSPVGRAALLALLLVGGEWAQEFTDQLVFGGALDRYGIVPRDPGSLSHILTAPFLHVGFPHLIAN
TAPLAVLAFMSALRGAARFVLATLVIVVVGGGLVWLLGRGGSDHLGASELVFGYFAYLVGVGWWERTPAAVAVALVTLLL
YGGILWGVLPTHPIISWEAHLFGFVAGLIAAALLHRRRPRAGRVSPYSPRSRF

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 23041; Mature: 22910

Theoretical pI: Translated: 12.03; Mature: 12.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRSPFPPQPPRRRSRSPVGRAALLALLLVGGEWAQEFTDQLVFGGALDRYGIVPRDPG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCCCCCCCC
SLSHILTAPFLHVGFPHLIANTAPLAVLAFMSALRGAARFVLATLVIVVVGGGLVWLLGR
HHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGSDHLGASELVFGYFAYLVGVGWWERTPAAVAVALVTLLLYGGILWGVLPTHPIISWEA
CCCCCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
HLFGFVAGLIAAALLHRRRPRAGRVSPYSPRSRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRRSPFPPQPPRRRSRSPVGRAALLALLLVGGEWAQEFTDQLVFGGALDRYGIVPRDPG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHCCCCCCCCC
SLSHILTAPFLHVGFPHLIANTAPLAVLAFMSALRGAARFVLATLVIVVVGGGLVWLLGR
HHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGSDHLGASELVFGYFAYLVGVGWWERTPAAVAVALVTLLLYGGILWGVLPTHPIISWEA
CCCCCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
HLFGFVAGLIAAALLHRRRPRAGRVSPYSPRSRF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]