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The map label for this gene is ywcA [H]

Identifier: 94985860

GI number: 94985860

Start: 1872563

End: 1874155

Strand: Reverse

Name: ywcA [H]

Synonym: Dgeo_1760

Alternate gene names: 94985860

Gene position: 1874155-1872563 (Counterclockwise)

Preceding gene: 94985861

Following gene: 94985859

Centisome position: 75.96

GC content: 64.22

Gene sequence:

>1593_bases
ATGACCTTTCTGTTGGCAGCCATCATCGTGGCGATCACGCTGGGCATCACCTTCTGGGCTGGGCGGCGCAACACCAGCGC
GAGCGACTTCTACGTGGCAGGTGGGCGGATCAGCGCTCCCCAAAATGGCATTGCCATCGCCGGGGACTACATGAGTGCAG
CCTCTTTCTTGGGGATCACCGGCCTCATCGCGCTGAACGGCTACGACGGCTTCATGTATTCGGTGGGCTGGTTTATCGCC
TACCTGACGGTGCTCTTTATCGTGGCTGAGCCGCTCAGGAATCTGGGCAAGTACACGCTGGCGGATATGCTGGTTTACCG
GCTCAAGGACCAGCGGGTGCGGACCTACGCCGCCATCAGCACCATCGTGATCAGCGCGTTTTACATGATTGCGCAGGTGG
TGGGCGCCGGGGCGCTGATCAGCCTGCTGTCGGGCGGCGTGCTGAAGGCCAGTGTGGCGATTCCGCTCGTTGGCGTGCTG
ATGATCATCTATGTCGTGGTCGGTGGGATGCTGGCGACGACCTGGGTGCAGATCGTCAAGGCTGTGCTGCTGATGTTCGC
CACGGTCGTGATGACCGTGCTGATCCTGAACCGCTTCGGCTGGAGCTTCTCCAACCTCTTGGGGGCCGCCGAGGCCAAGA
ACGGCGCGGACTTCCTGGGCGCGGGCCTGAAGTACAAGAACCCCATCGACCTCATCTCGCTGAGCCTGGCGCTGGTGCTG
GGGACGGCGGGCTTGCCGCACATCCTGGTGCGCTTCTACACGGTGCCCACCGCGCAGGATGCTCGCAAGAGCGTGGTGTG
GGCGATGGTTTTGATCGGTGCTTTCTACGTGATGACCGCCTTTATGGGCAATGCGGCGAATGTGCTGGTGGGCAAGGATG
CCATCGAGGCGGCCAACAAGGCGGGCAACATGGCCGCGCCGCTGCTCGCGGAGGCCCTCTTCGGCGGCAAGGGCACGTTT
GGCGGTGAGCTGGGCTTGGCCTTTGTGACCGCCGTAGCGTTTGCCACCATCCTGGCGGTGGTGGCGGGCCTGACCATCGC
CGCTAGCACCTCCTTCACCCACGACATCTACAACGGTGTGATTCGCCGGGGGCAGGCCACCGGGCGCGAGGAGTTCCGGG
TCGCCCGCATTGCCACCGTCGCGGTCGGTGTGATCGCCATCCTGCTGGGTCTTCTGGCCCAGACACAGAACGTGGCCTTC
TTGGTCGCGCTCGCCTTTGCGATCGCGGCGTCGTCCAACCTGCCGGTGATCCTGTTTACACTGTTCTGGCGCCGTTTCAA
TGCCACAGGGGCGATCTGGGGCATCGTCGGTGGCATCCTGACTTGCCTGGTGCTGATCGTCCTCAGCCCCAACATTATGG
GCATCGATCCCGCCGACAAGACAACCGGCCGTCACCCCATCCAGGCGGCCCCGATCTTCCCGCTGGAAAATCCCGGCATC
ATCTCCATCCCCGCTGGGTTTGCCTTCGCCGCCCTGGGCACGCTGATAGGTGCGCGCCGCCGCCGCGAGGACGCCGAAGC
GGCCTTCGAGGAGATGCAGTTCCGCGCCTACACCGGGGCAGGCATGGACGGCAGCGTCGCGGCGCACGACTGA

Upstream 100 bases:

>100_bases
ATGTGTTCGCCTTTGCGGAATTTGTCATGGGCTGGGTGATGGCCGCAATCTACGTGGTGCGTGCCCGGCAGTTTGACCGT
TTGGCCCAGGAGGCGCAGCG

Downstream 100 bases:

>100_bases
GACGCTGTGATGTCCTGAGACGTTGTGATCCAGCCTCCGGTCGCGCGCTGGGGGCTTTCGCATCCCTCTCTGCTTGGACT
CAGTCCAGTACCCCGCGCGT

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTFLLAAIIVAITLGITFWAGRRNTSASDFYVAGGRISAPQNGIAIAGDYMSAASFLGITGLIALNGYDGFMYSVGWFIA
YLTVLFIVAEPLRNLGKYTLADMLVYRLKDQRVRTYAAISTIVISAFYMIAQVVGAGALISLLSGGVLKASVAIPLVGVL
MIIYVVVGGMLATTWVQIVKAVLLMFATVVMTVLILNRFGWSFSNLLGAAEAKNGADFLGAGLKYKNPIDLISLSLALVL
GTAGLPHILVRFYTVPTAQDARKSVVWAMVLIGAFYVMTAFMGNAANVLVGKDAIEAANKAGNMAAPLLAEALFGGKGTF
GGELGLAFVTAVAFATILAVVAGLTIAASTSFTHDIYNGVIRRGQATGREEFRVARIATVAVGVIAILLGLLAQTQNVAF
LVALAFAIAASSNLPVILFTLFWRRFNATGAIWGIVGGILTCLVLIVLSPNIMGIDPADKTTGRHPIQAAPIFPLENPGI
ISIPAGFAFAALGTLIGARRRREDAEAAFEEMQFRAYTGAGMDGSVAAHD

Sequences:

>Translated_530_residues
MTFLLAAIIVAITLGITFWAGRRNTSASDFYVAGGRISAPQNGIAIAGDYMSAASFLGITGLIALNGYDGFMYSVGWFIA
YLTVLFIVAEPLRNLGKYTLADMLVYRLKDQRVRTYAAISTIVISAFYMIAQVVGAGALISLLSGGVLKASVAIPLVGVL
MIIYVVVGGMLATTWVQIVKAVLLMFATVVMTVLILNRFGWSFSNLLGAAEAKNGADFLGAGLKYKNPIDLISLSLALVL
GTAGLPHILVRFYTVPTAQDARKSVVWAMVLIGAFYVMTAFMGNAANVLVGKDAIEAANKAGNMAAPLLAEALFGGKGTF
GGELGLAFVTAVAFATILAVVAGLTIAASTSFTHDIYNGVIRRGQATGREEFRVARIATVAVGVIAILLGLLAQTQNVAF
LVALAFAIAASSNLPVILFTLFWRRFNATGAIWGIVGGILTCLVLIVLSPNIMGIDPADKTTGRHPIQAAPIFPLENPGI
ISIPAGFAFAALGTLIGARRRREDAEAAFEEMQFRAYTGAGMDGSVAAHD
>Mature_529_residues
TFLLAAIIVAITLGITFWAGRRNTSASDFYVAGGRISAPQNGIAIAGDYMSAASFLGITGLIALNGYDGFMYSVGWFIAY
LTVLFIVAEPLRNLGKYTLADMLVYRLKDQRVRTYAAISTIVISAFYMIAQVVGAGALISLLSGGVLKASVAIPLVGVLM
IIYVVVGGMLATTWVQIVKAVLLMFATVVMTVLILNRFGWSFSNLLGAAEAKNGADFLGAGLKYKNPIDLISLSLALVLG
TAGLPHILVRFYTVPTAQDARKSVVWAMVLIGAFYVMTAFMGNAANVLVGKDAIEAANKAGNMAAPLLAEALFGGKGTFG
GELGLAFVTAVAFATILAVVAGLTIAASTSFTHDIYNGVIRRGQATGREEFRVARIATVAVGVIAILLGLLAQTQNVAFL
VALAFAIAASSNLPVILFTLFWRRFNATGAIWGIVGGILTCLVLIVLSPNIMGIDPADKTTGRHPIQAAPIFPLENPGII
SIPAGFAFAALGTLIGARRRREDAEAAFEEMQFRAYTGAGMDGSVAAHD

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=468, Percent_Identity=24.7863247863248, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790503, Length=531, Percent_Identity=47.6459510357815, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1787251, Length=453, Percent_Identity=27.8145695364238, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55666; Mature: 55535

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLLAAIIVAITLGITFWAGRRNTSASDFYVAGGRISAPQNGIAIAGDYMSAASFLGIT
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEECCCCCCEEEECHHHHHHHHHHHH
GLIALNGYDGFMYSVGWFIAYLTVLFIVAEPLRNLGKYTLADMLVYRLKDQRVRTYAAIS
HEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVISAFYMIAQVVGAGALISLLSGGVLKASVAIPLVGVLMIIYVVVGGMLATTWVQIVK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLLMFATVVMTVLILNRFGWSFSNLLGAAEAKNGADFLGAGLKYKNPIDLISLSLALVL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHH
GTAGLPHILVRFYTVPTAQDARKSVVWAMVLIGAFYVMTAFMGNAANVLVGKDAIEAANK
HCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHH
AGNMAAPLLAEALFGGKGTFGGELGLAFVTAVAFATILAVVAGLTIAASTSFTHDIYNGV
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IRRGQATGREEFRVARIATVAVGVIAILLGLLAQTQNVAFLVALAFAIAASSNLPVILFT
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHH
LFWRRFNATGAIWGIVGGILTCLVLIVLSPNIMGIDPADKTTGRHPIQAAPIFPLENPGI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
ISIPAGFAFAALGTLIGARRRREDAEAAFEEMQFRAYTGAGMDGSVAAHD
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCC
>Mature Secondary Structure 
TFLLAAIIVAITLGITFWAGRRNTSASDFYVAGGRISAPQNGIAIAGDYMSAASFLGIT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEECCCCCCEEEECHHHHHHHHHHHH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EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]