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The map label for this gene is lepB [H]

Identifier: 94985749

GI number: 94985749

Start: 1751574

End: 1752227

Strand: Reverse

Name: lepB [H]

Synonym: Dgeo_1649

Alternate gene names: 94985749

Gene position: 1752227-1751574 (Counterclockwise)

Preceding gene: 94985751

Following gene: 94985743

Centisome position: 71.02

GC content: 65.29

Gene sequence:

>654_bases
GTGTTGGGGGGACTCCTCCCGGTGTGGCTCTTCACGACCTTCGTAGCGACCCTCGCCCGCGTGGATGGCAACAGCATGCA
TCCCACCCTTCACAGCGGCGATCTGCTGTTGCTGCTGAAGTATCCGCGCTGGCTACGGGCCTGGGGTCTGCCCACCGCCT
ACCCGCGCCGGGGGGACCTGCTGATCTTCAAGGCACCCGCGGACAGTCCCTATAGTTATGAGACGCTGTGGGGTGTGCGG
CATCGTCCCTACAACGTCAAGCGGGTGTTGGCCCTCCCTGGGGACACCGTCGCCATCGAGGACGGACAATTGATCGTAAA
CGGGCGACCCCTCGCCGAGAGTTATGTGAATGACGGCGTGCTCAATGACCAGCCGCCGCTGCGCGTTCCACCTGGCAAGG
TGTGGGTGATGGGCGATAACCGCCTCGTCGGGGAAAGTTTGGACTCGCGCGTCTATGGTTCGGTTGATCTCCGCGACGCA
GCCGGTCCCGCGAACCTCCGGCTGTGGCCCGACCCGGGATGGGTGAGCCGCTCAGCTACTCCTCCGGCAACCGCTCCCCG
GCCCGCACCGGCACAGTCAGCCAGTTCTCGCGCGGCGGCAGAGGACAGGTCCAGCCTTCACCATAGGCGCAGTAGGGGTG
ATAGGCGAGGTTGA

Upstream 100 bases:

>100_bases
TTGGCCTGTTGAGCCGCCTGCTAGCATGCCCCGTGTGACCCCGACGCCCACCGGTGACCGTACCCGCTCCGGCAGCTTCC
GGGCCTTCTGGCGGGTTTGG

Downstream 100 bases:

>100_bases
AGTCCAGCTGGGCTTTCAGGCCCTCGGGTGTCGGGGTCAGCGGCGCATCCAGATAGCGCCCCGCACCATAGGTTTCGGTC
CCGCTCGTCGCGTCGCGGAA

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MLGGLLPVWLFTTFVATLARVDGNSMHPTLHSGDLLLLLKYPRWLRAWGLPTAYPRRGDLLIFKAPADSPYSYETLWGVR
HRPYNVKRVLALPGDTVAIEDGQLIVNGRPLAESYVNDGVLNDQPPLRVPPGKVWVMGDNRLVGESLDSRVYGSVDLRDA
AGPANLRLWPDPGWVSRSATPPATAPRPAPAQSASSRAAAEDRSSLHHRRSRGDRRG

Sequences:

>Translated_217_residues
MLGGLLPVWLFTTFVATLARVDGNSMHPTLHSGDLLLLLKYPRWLRAWGLPTAYPRRGDLLIFKAPADSPYSYETLWGVR
HRPYNVKRVLALPGDTVAIEDGQLIVNGRPLAESYVNDGVLNDQPPLRVPPGKVWVMGDNRLVGESLDSRVYGSVDLRDA
AGPANLRLWPDPGWVSRSATPPATAPRPAPAQSASSRAAAEDRSSLHHRRSRGDRRG
>Mature_217_residues
MLGGLLPVWLFTTFVATLARVDGNSMHPTLHSGDLLLLLKYPRWLRAWGLPTAYPRRGDLLIFKAPADSPYSYETLWGVR
HRPYNVKRVLALPGDTVAIEDGQLIVNGRPLAESYVNDGVLNDQPPLRVPPGKVWVMGDNRLVGESLDSRVYGSVDLRDA
AGPANLRLWPDPGWVSRSATPPATAPRPAPAQSASSRAAAEDRSSLHHRRSRGDRRG

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23854; Mature: 23854

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGGLLPVWLFTTFVATLARVDGNSMHPTLHSGDLLLLLKYPRWLRAWGLPTAYPRRGDL
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCHHHHHCCCCCCCCCCCCE
LIFKAPADSPYSYETLWGVRHRPYNVKRVLALPGDTVAIEDGQLIVNGRPLAESYVNDGV
EEEECCCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEECCEEEECCCCHHHHHHCCCC
LNDQPPLRVPPGKVWVMGDNRLVGESLDSRVYGSVDLRDAAGPANLRLWPDPGWVSRSAT
CCCCCCCCCCCCEEEEEECCEEECCCCCCCEECCEECCCCCCCCCEEECCCCCCCCCCCC
PPATAPRPAPAQSASSRAAAEDRSSLHHRRSRGDRRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLGGLLPVWLFTTFVATLARVDGNSMHPTLHSGDLLLLLKYPRWLRAWGLPTAYPRRGDL
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCHHHHHCCCCCCCCCCCCE
LIFKAPADSPYSYETLWGVRHRPYNVKRVLALPGDTVAIEDGQLIVNGRPLAESYVNDGV
EEEECCCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEECCEEEECCCCHHHHHHCCCC
LNDQPPLRVPPGKVWVMGDNRLVGESLDSRVYGSVDLRDAAGPANLRLWPDPGWVSRSAT
CCCCCCCCCCCCEEEEEECCEEECCCCCCCEECCEECCCCCCCCCEEECCCCCCCCCCCC
PPATAPRPAPAQSASSRAAAEDRSSLHHRRSRGDRRG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA