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The map label for this gene is trxB [H]

Identifier: 94985676

GI number: 94985676

Start: 1675211

End: 1676194

Strand: Reverse

Name: trxB [H]

Synonym: Dgeo_1576

Alternate gene names: 94985676

Gene position: 1676194-1675211 (Counterclockwise)

Preceding gene: 94985679

Following gene: 94985675

Centisome position: 67.94

GC content: 64.23

Gene sequence:

>984_bases
ATGACCAGCGCCTCTCAGCACTCCCATGACTACGACGTGGTGATCGTCGGTGGCGGCCCGGCCGGGCTGACCGCTGCGAT
CTACACCGGCCGCGCCAGCCTGAGCACCTTGGTGCTGGAAAAAGGCCTGCCGGGCGGACAAATCGCCCAGACCGAGGAAG
TCGAGAACTACCCGGGCTTTCCCGAGCCGATTCACGGGATGGAGCTTGCCCAGCGCATGGTGCAGCAGGCCGAGAAATTC
GGCGCGCGCATCGAGATGGACGAGGTGGAGGCCATCACGCACGCCGAGGACGACCGCGAGCATGTCTATCCCTTTACCAT
TCGCGGCTACAGCGGTACCTACCGCGCCAAGGCCGTCATCCTCGCGACCGGTGCGAACCCCAAACGCCTGAATGTTCCCG
GCGAGGAGCACTTCTGGGGCAAGGGGGTGAGCACCTGCGCCACCTGTGACGGCTTTTTCTACCGTGGCAAAAAGGTGGTC
GTGGTGGGTGGCGGGGACGCGGCGGTCGAGGAGGGCCTCTTCCTGACCAAGTTTGCAGATGAGGTGACGCTGATTCACCG
CCGCGATACCCTCCGTGCCAATAAGGTGGCCCAGGCCCGCGCCTTTGCGAACCCCAAGATGAAATTTGTCTGGGACACGG
TGGTTGAGGAGATTCTGGGCCAGGAGCAGGTGATGGGCGTGCGGCTGAAGAACCTCAAGACGGGGGAAACGAGCGAGTTC
CCGACCGACGGCGTGTTTATCTTTATCGGGCACGTCCCGAACACCGAGTTCGTGCGCGATACCGTGAAGCTCCGTCCGGA
CGGCTATGTCGAGGTGACCGACGAGATCTACACCAGTGTGCCCCTGCTGTTTGCGGCGGGCGACGTTTCGGACTACGTGT
ACCGCCAGCTCGCGACCAGCGTGGGGGCGGGCACCCGCGCCGCCATGAGCGCCGAGCGGGCACTGGCTGCTCTGGAACTC
GAAACCGAAACCGCCGCCGACTGA

Upstream 100 bases:

>100_bases
CCATGGCGCGCTGTGCGCAAGCAGGTCGGGGGCTTCCCAGTTTAAAAAACAAAGTGCATGTCTGACCATCCCCGAATGTG
CTCGGTGGTACGCTTCGTGT

Downstream 100 bases:

>100_bases
ACCGGGGCGAGCGGGAGGGAAGAAACGCTCGCGTCCCCTTCCCGTATCCCCTTCCCGTATCCTGGGTCTATGCATCCCCT
GACCCCCATGGCCCGGCTGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35 [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTSASQHSHDYDVVIVGGGPAGLTAAIYTGRASLSTLVLEKGLPGGQIAQTEEVENYPGFPEPIHGMELAQRMVQQAEKF
GARIEMDEVEAITHAEDDREHVYPFTIRGYSGTYRAKAVILATGANPKRLNVPGEEHFWGKGVSTCATCDGFFYRGKKVV
VVGGGDAAVEEGLFLTKFADEVTLIHRRDTLRANKVAQARAFANPKMKFVWDTVVEEILGQEQVMGVRLKNLKTGETSEF
PTDGVFIFIGHVPNTEFVRDTVKLRPDGYVEVTDEIYTSVPLLFAAGDVSDYVYRQLATSVGAGTRAAMSAERALAALEL
ETETAAD

Sequences:

>Translated_327_residues
MTSASQHSHDYDVVIVGGGPAGLTAAIYTGRASLSTLVLEKGLPGGQIAQTEEVENYPGFPEPIHGMELAQRMVQQAEKF
GARIEMDEVEAITHAEDDREHVYPFTIRGYSGTYRAKAVILATGANPKRLNVPGEEHFWGKGVSTCATCDGFFYRGKKVV
VVGGGDAAVEEGLFLTKFADEVTLIHRRDTLRANKVAQARAFANPKMKFVWDTVVEEILGQEQVMGVRLKNLKTGETSEF
PTDGVFIFIGHVPNTEFVRDTVKLRPDGYVEVTDEIYTSVPLLFAAGDVSDYVYRQLATSVGAGTRAAMSAERALAALEL
ETETAAD
>Mature_326_residues
TSASQHSHDYDVVIVGGGPAGLTAAIYTGRASLSTLVLEKGLPGGQIAQTEEVENYPGFPEPIHGMELAQRMVQQAEKFG
ARIEMDEVEAITHAEDDREHVYPFTIRGYSGTYRAKAVILATGANPKRLNVPGEEHFWGKGVSTCATCDGFFYRGKKVVV
VGGGDAAVEEGLFLTKFADEVTLIHRRDTLRANKVAQARAFANPKMKFVWDTVVEEILGQEQVMGVRLKNLKTGETSEFP
TDGVFIFIGHVPNTEFVRDTVKLRPDGYVEVTDEIYTSVPLLFAAGDVSDYVYRQLATSVGAGTRAAMSAERALAALELE
TETAAD

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=306, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226437568, Length=306, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI65787454, Length=306, Percent_Identity=27.4509803921569, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787114, Length=324, Percent_Identity=42.9012345679012, Blast_Score=242, Evalue=2e-65,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=30.3225806451613, Blast_Score=141, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=41.7721518987342, Blast_Score=236, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=40, Blast_Score=228, Evalue=8e-61,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35554; Mature: 35423

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSASQHSHDYDVVIVGGGPAGLTAAIYTGRASLSTLVLEKGLPGGQIAQTEEVENYPGF
CCCCCCCCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
PEPIHGMELAQRMVQQAEKFGARIEMDEVEAITHAEDDREHVYPFTIRGYSGTYRAKAVI
CCCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEE
LATGANPKRLNVPGEEHFWGKGVSTCATCDGFFYRGKKVVVVGGGDAAVEEGLFLTKFAD
EEECCCCCEECCCCCCCCCCCCCCHHHHCCCCEECCCEEEEECCCCHHHHCCEEEEECCC
EVTLIHRRDTLRANKVAQARAFANPKMKFVWDTVVEEILGQEQVMGVRLKNLKTGETSEF
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCC
PTDGVFIFIGHVPNTEFVRDTVKLRPDGYVEVTDEIYTSVPLLFAAGDVSDYVYRQLATS
CCCCEEEEEECCCCHHHHHHHHEECCCCCEEECHHHHHCCCEEEEECCHHHHHHHHHHHH
VGAGTRAAMSAERALAALELETETAAD
HCCCCHHHHHHHHHHHEEEECCCCCCC
>Mature Secondary Structure 
TSASQHSHDYDVVIVGGGPAGLTAAIYTGRASLSTLVLEKGLPGGQIAQTEEVENYPGF
CCCCCCCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
PEPIHGMELAQRMVQQAEKFGARIEMDEVEAITHAEDDREHVYPFTIRGYSGTYRAKAVI
CCCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEE
LATGANPKRLNVPGEEHFWGKGVSTCATCDGFFYRGKKVVVVGGGDAAVEEGLFLTKFAD
EEECCCCCEECCCCCCCCCCCCCCHHHHCCCCEECCCEEEEECCCCHHHHCCEEEEECCC
EVTLIHRRDTLRANKVAQARAFANPKMKFVWDTVVEEILGQEQVMGVRLKNLKTGETSEF
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCC
PTDGVFIFIGHVPNTEFVRDTVKLRPDGYVEVTDEIYTSVPLLFAAGDVSDYVYRQLATS
CCCCEEEEEECCCCHHHHHHHHEECCCCCEEECHHHHHCCCEEEEECCHHHHHHHHHHHH
VGAGTRAAMSAERALAALELETETAAD
HCCCCHHHHHHHHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]