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The map label for this gene is aroA [H]

Identifier: 94985672

GI number: 94985672

Start: 1671359

End: 1672498

Strand: Reverse

Name: aroA [H]

Synonym: Dgeo_1572

Alternate gene names: 94985672

Gene position: 1672498-1671359 (Counterclockwise)

Preceding gene: 94985673

Following gene: 94985668

Centisome position: 67.79

GC content: 66.84

Gene sequence:

>1140_bases
TTGACTAGCGGTGTGAGGCCAGAACACGAAGCGCTTTTCTACACTGGCCGCATGACCCAACGCAGTATCGACGACCTCCG
CGCCGAGGTCGATGCCATCAACCGTGACCTTCTGACCCTGCTCTCGCGCCGTGGCGAGGTGGTCGCGCAGATCGGCCGGG
CCAAAACCCAGGAGGGCCGCCCGCAGCACTACGATCCCGCCCGCGAGGAACAGCAGCTGCGCGTGCTGGAGCAGCTGAAC
CCTGGCCCCTTCACGAGCGCCGCCGTCAAGGCCATCTTCAAGGAAATTTTCAAGGCCAGCCTGGACCTTGAGGAGAGCAA
CGACAAAAAGCAGCTGCTGGTGTCACGTAAGGTCAAACCCGAGGACACCCAGCTCGACATCGACGGCGTCCGCATCGGCG
GGGGCGCCCCGCCCGTCGTGATTGCGGGGCCCTGCTCCATCGAGTCGGAAGAGCAGATGGAGGAGACGGCCCGTTTCCTG
GCCTCGCGCGGCGTGAAGATCCTGCGCGGCGGTGCCTACAAACCCCGCACCAGTCCCTACGGCTTCCAGGGCATGGGCGT
GGACGGCTTGATCATCGGCGGGCGGGCGGCGCGCGAGAATGGCATGCTCTTTGTGACCGAAGTGATGGACACCCGCGATG
TGGAGGTCGTGGCCGAGCACGCCGACATCCTCCAGGTGGGCGCGCGCAACATGCACAACTTCAGCCTGCTCCGTGAAGTG
GGCCGCGCCCGGCGCCCGGTGCTGCTCAAGCGCGGCCTGAGCGCCACCATCGAAGAGTGGCTCTATGCCGCCGAGTACAT
CCTCTCGGAGGGGAACCCCGAAGTGATCCTCTGCGAGCGCGGCATTCGCACCTTTGAGAAGTGGACCCGCAACACCCTCG
ACCTCTCGGCGGTGGCTCTTGCCAAGCAGGAGACGCACCTCCCGGTCATCGTGGACGTGACGCACGCCGCCGGACGCCGC
GACCTGCTGATCCCGCTTGCCAGAGCCGCCCTTGCCGTCGGCGCCGACGGCATCCACGTCGAGGTCCACCCCAGCCCCGC
CACCGCCCTGAGCGACAACGAGCAGCAGCTCGACTTCGCGGGGTACGACCGCTTCCTCGACGCGCTGGCGCCACTGCTCA
AGGTGGCCGCGACCGTCTGA

Upstream 100 bases:

>100_bases
GAGGCTGAGGCCCGCGAACTGTACGCAGCGCTCTCGCGGGTGGCGGTGCACATGGTGAATACGCCGGAAGCGGAGCCAGA
ACCTGGACAGGTTTTTTCAA

Downstream 100 bases:

>100_bases
TTTCGCCGCCTGCGAAGCGAGTGATCCCCGGAATAGGCCCAGCCCTCGCCCGAGATCCTGACACCGTTATGAACAGAAAG
GCGGACCGGAAGCCCTGGTC

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTSGVRPEHEALFYTGRMTQRSIDDLRAEVDAINRDLLTLLSRRGEVVAQIGRAKTQEGRPQHYDPAREEQQLRVLEQLN
PGPFTSAAVKAIFKEIFKASLDLEESNDKKQLLVSRKVKPEDTQLDIDGVRIGGGAPPVVIAGPCSIESEEQMEETARFL
ASRGVKILRGGAYKPRTSPYGFQGMGVDGLIIGGRAARENGMLFVTEVMDTRDVEVVAEHADILQVGARNMHNFSLLREV
GRARRPVLLKRGLSATIEEWLYAAEYILSEGNPEVILCERGIRTFEKWTRNTLDLSAVALAKQETHLPVIVDVTHAAGRR
DLLIPLARAALAVGADGIHVEVHPSPATALSDNEQQLDFAGYDRFLDALAPLLKVAATV

Sequences:

>Translated_379_residues
MTSGVRPEHEALFYTGRMTQRSIDDLRAEVDAINRDLLTLLSRRGEVVAQIGRAKTQEGRPQHYDPAREEQQLRVLEQLN
PGPFTSAAVKAIFKEIFKASLDLEESNDKKQLLVSRKVKPEDTQLDIDGVRIGGGAPPVVIAGPCSIESEEQMEETARFL
ASRGVKILRGGAYKPRTSPYGFQGMGVDGLIIGGRAARENGMLFVTEVMDTRDVEVVAEHADILQVGARNMHNFSLLREV
GRARRPVLLKRGLSATIEEWLYAAEYILSEGNPEVILCERGIRTFEKWTRNTLDLSAVALAKQETHLPVIVDVTHAAGRR
DLLIPLARAALAVGADGIHVEVHPSPATALSDNEQQLDFAGYDRFLDALAPLLKVAATV
>Mature_378_residues
TSGVRPEHEALFYTGRMTQRSIDDLRAEVDAINRDLLTLLSRRGEVVAQIGRAKTQEGRPQHYDPAREEQQLRVLEQLNP
GPFTSAAVKAIFKEIFKASLDLEESNDKKQLLVSRKVKPEDTQLDIDGVRIGGGAPPVVIAGPCSIESEEQMEETARFLA
SRGVKILRGGAYKPRTSPYGFQGMGVDGLIIGGRAARENGMLFVTEVMDTRDVEVVAEHADILQVGARNMHNFSLLREVG
RARRPVLLKRGLSATIEEWLYAAEYILSEGNPEVILCERGIRTFEKWTRNTLDLSAVALAKQETHLPVIVDVTHAAGRRD
LLIPLARAALAVGADGIHVEVHPSPATALSDNEQQLDFAGYDRFLDALAPLLKVAATV

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 41686; Mature: 41555

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGVRPEHEALFYTGRMTQRSIDDLRAEVDAINRDLLTLLSRRGEVVAQIGRAKTQEGR
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
PQHYDPAREEQQLRVLEQLNPGPFTSAAVKAIFKEIFKASLDLEESNDKKQLLVSRKVKP
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
EDTQLDIDGVRIGGGAPPVVIAGPCSIESEEQMEETARFLASRGVKILRGGAYKPRTSPY
CCCEEEECCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
GFQGMGVDGLIIGGRAARENGMLFVTEVMDTRDVEVVAEHADILQVGARNMHNFSLLREV
CCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
GRARRPVLLKRGLSATIEEWLYAAEYILSEGNPEVILCERGIRTFEKWTRNTLDLSAVAL
HHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCHHHHHH
AKQETHLPVIVDVTHAAGRRDLLIPLARAALAVGADGIHVEVHPSPATALSDNEQQLDFA
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHCCHH
GYDRFLDALAPLLKVAATV
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSGVRPEHEALFYTGRMTQRSIDDLRAEVDAINRDLLTLLSRRGEVVAQIGRAKTQEGR
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
PQHYDPAREEQQLRVLEQLNPGPFTSAAVKAIFKEIFKASLDLEESNDKKQLLVSRKVKP
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
EDTQLDIDGVRIGGGAPPVVIAGPCSIESEEQMEETARFLASRGVKILRGGAYKPRTSPY
CCCEEEECCEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
GFQGMGVDGLIIGGRAARENGMLFVTEVMDTRDVEVVAEHADILQVGARNMHNFSLLREV
CCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
GRARRPVLLKRGLSATIEEWLYAAEYILSEGNPEVILCERGIRTFEKWTRNTLDLSAVAL
HHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCHHHHHH
AKQETHLPVIVDVTHAAGRRDLLIPLARAALAVGADGIHVEVHPSPATALSDNEQQLDFA
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHCCHH
GYDRFLDALAPLLKVAATV
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]