Click here to switch to the map view.

The map label for this gene is purN [H]

Identifier: 94985646

GI number: 94985646

Start: 1647302

End: 1647874

Strand: Reverse

Name: purN [H]

Synonym: Dgeo_1546

Alternate gene names: 94985646

Gene position: 1647874-1647302 (Counterclockwise)

Preceding gene: 94985647

Following gene: 94985640

Centisome position: 66.79

GC content: 69.81

Gene sequence:

>573_bases
ATGATCCTCGGCTTCCTCGCCTCTCATGGCGGCAGCGCGGCCCGCTTTCTGACGGCGGCCTGTCGGGATGGGCGTCTGAA
CGCGGTGCCGGTCGCGCTCGCCAGCAACAACAGCGGCAGCCCGGCGCTCGCCTGGGCGCGGGAGGCGGGCCTGCGCACAG
CGCACCTCAGCCGCGCGAAATATCCTGACCCAGATGCCCTCGACGCGGCGATTCTGGCCTTTTTGCAAGACGCAGGAGTG
GATACGTTGGTCCTGAGTGGCTATATGAAGGCGCTGGGGCCGCGGGTGCTTTCGGCCTACGCAGGCCGGGTGCTCAATAT
TCACCCCAGCTTGCTCCCACGCCACGGTGGGCGCGGTATGTATGGCGACCGGGTGCATGAGGCGGTGCTGGCCTCCGGCG
ACACCGAATCCGGCGCGACTGTGCACCTCGTCACCGCCGGGATCGACGAGGGACCGGTGCTGGCCCAGGTGCGGGTGCCG
GTGTTGCCCGGCGACACCGTGGCGACCCTCAAGGCGCGGGTGCAGGCCCTGGAAGGCGAGCTGCTGCTCTCGGCGCTGCG
GGCGCTGGCGTGA

Upstream 100 bases:

>100_bases
GCCTTCCTGCTTCAGGAGATCGGGAAGTGAAGTTGGAGGGCGAGGGGCAGTCTTGCTCCATTCACCCCTCCTCGCTTTTC
GCGGACGGCGCGGAGCGCCC

Downstream 100 bases:

>100_bases
TTTGCATTCTGTGACCTGAGCCGCTAATCTGCTGTGCGCTGGAACGGTGCCCGAGTGGTTGAAGGGGCACGCCTGGAAAG
CGTGTATACGGGCAACCGTA

Product: formyl transferase-like protein

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MILGFLASHGGSAARFLTAACRDGRLNAVPVALASNNSGSPALAWAREAGLRTAHLSRAKYPDPDALDAAILAFLQDAGV
DTLVLSGYMKALGPRVLSAYAGRVLNIHPSLLPRHGGRGMYGDRVHEAVLASGDTESGATVHLVTAGIDEGPVLAQVRVP
VLPGDTVATLKARVQALEGELLLSALRALA

Sequences:

>Translated_190_residues
MILGFLASHGGSAARFLTAACRDGRLNAVPVALASNNSGSPALAWAREAGLRTAHLSRAKYPDPDALDAAILAFLQDAGV
DTLVLSGYMKALGPRVLSAYAGRVLNIHPSLLPRHGGRGMYGDRVHEAVLASGDTESGATVHLVTAGIDEGPVLAQVRVP
VLPGDTVATLKARVQALEGELLLSALRALA
>Mature_190_residues
MILGFLASHGGSAARFLTAACRDGRLNAVPVALASNNSGSPALAWAREAGLRTAHLSRAKYPDPDALDAAILAFLQDAGV
DTLVLSGYMKALGPRVLSAYAGRVLNIHPSLLPRHGGRGMYGDRVHEAVLASGDTESGATVHLVTAGIDEGPVLAQVRVP
VLPGDTVATLKARVQALEGELLLSALRALA

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=185, Percent_Identity=34.5945945945946, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI209869995, Length=185, Percent_Identity=34.5945945945946, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI209869993, Length=185, Percent_Identity=34.5945945945946, Blast_Score=101, Evalue=4e-22,
Organism=Escherichia coli, GI1788846, Length=178, Percent_Identity=37.0786516853933, Blast_Score=116, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17567511, Length=188, Percent_Identity=30.3191489361702, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582400, Length=175, Percent_Identity=34.8571428571429, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 19588; Mature: 19588

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGFLASHGGSAARFLTAACRDGRLNAVPVALASNNSGSPALAWAREAGLRTAHLSRAK
CEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCCC
YPDPDALDAAILAFLQDAGVDTLVLSGYMKALGPRVLSAYAGRVLNIHPSLLPRHGGRGM
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
YGDRVHEAVLASGDTESGATVHLVTAGIDEGPVLAQVRVPVLPGDTVATLKARVQALEGE
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LLLSALRALA
HHHHHHHHHC
>Mature Secondary Structure
MILGFLASHGGSAARFLTAACRDGRLNAVPVALASNNSGSPALAWAREAGLRTAHLSRAK
CEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHCCCHHHHHCCCC
YPDPDALDAAILAFLQDAGVDTLVLSGYMKALGPRVLSAYAGRVLNIHPSLLPRHGGRGM
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
YGDRVHEAVLASGDTESGATVHLVTAGIDEGPVLAQVRVPVLPGDTVATLKARVQALEGE
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LLLSALRALA
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]