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The map label for this gene is sigW [H]

Identifier: 94985619

GI number: 94985619

Start: 1610247

End: 1610822

Strand: Reverse

Name: sigW [H]

Synonym: Dgeo_1519

Alternate gene names: 94985619

Gene position: 1610822-1610247 (Counterclockwise)

Preceding gene: 94985621

Following gene: 94985618

Centisome position: 65.29

GC content: 68.06

Gene sequence:

>576_bases
GTGACTGCCGAGCCGGACATCCTCACGCCCGAGATGCTCGCCCGCCTGACGGCCGGAGAGGAGGTCGCCTGGTACGACTT
CGTGAGCGCCTATGAGGGGCGCATGTACGCCTACCTGTACCGGCTGGAAGGCAACGCCGAAGACGCCCTCGACCTCACCC
AGGAAGTCTTTTACCGCGCCTGGCGCAGCATCCGGACCTTCCGCGCGGGCGAGCGGGTGCTGCCCTGGTTGTACCAGGTG
GCCCGCAACACCCAGATCGAGTCCCACCGCCGCAAGCAGCTTCAGCGCTTCAGCCTGGAAGAGGCGCGGGAGGACGTGGG
CTTTGAGGTCACCAGTGGCGCCCGCTCTCCAGCGCAGGCCGCCGAGAGCGCCGACGCCCAGGACCGCGTGCAACATGCGC
TGATGCGGCTGCCGCAGGAATACCGCGAGGCCGTCGTGCTGCGCTTTGTCGAGGACCTCCCCTACGACGAGATCGCCCGC
ATTCAGGGCGTGGCCGTCGGCACCGCCAAGAGCCGTGTCTTCCGCGCCAAGGAGCAATTGGCGGACCTGCTGGCCGACGT
GGCCGATGTGCATTGA

Upstream 100 bases:

>100_bases
GCGGGCGTCTTGCAGAAGATCTTGCGGGGGAGCGCGTTTGCTCTCGCTTCCGCCAAAGGGCTGACGCGCAGTCGGTCCCT
AGAGGGTATGGTGAGGAGAC

Downstream 100 bases:

>100_bases
GCCGATGTGCATTGAGCCGATGTGCATTGAATGTGCATTGAAGAGTGCAGTGAGGAATACGCGCGTGGACAGACCAAAAG
CCGGGTTCCGCGCCCTACAC

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MTAEPDILTPEMLARLTAGEEVAWYDFVSAYEGRMYAYLYRLEGNAEDALDLTQEVFYRAWRSIRTFRAGERVLPWLYQV
ARNTQIESHRRKQLQRFSLEEAREDVGFEVTSGARSPAQAAESADAQDRVQHALMRLPQEYREAVVLRFVEDLPYDEIAR
IQGVAVGTAKSRVFRAKEQLADLLADVADVH

Sequences:

>Translated_191_residues
MTAEPDILTPEMLARLTAGEEVAWYDFVSAYEGRMYAYLYRLEGNAEDALDLTQEVFYRAWRSIRTFRAGERVLPWLYQV
ARNTQIESHRRKQLQRFSLEEAREDVGFEVTSGARSPAQAAESADAQDRVQHALMRLPQEYREAVVLRFVEDLPYDEIAR
IQGVAVGTAKSRVFRAKEQLADLLADVADVH
>Mature_190_residues
TAEPDILTPEMLARLTAGEEVAWYDFVSAYEGRMYAYLYRLEGNAEDALDLTQEVFYRAWRSIRTFRAGERVLPWLYQVA
RNTQIESHRRKQLQRFSLEEAREDVGFEVTSGARSPAQAAESADAQDRVQHALMRLPQEYREAVVLRFVEDLPYDEIARI
QGVAVGTAKSRVFRAKEQLADLLADVADVH

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=180, Percent_Identity=31.6666666666667, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21930; Mature: 21799

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEPDILTPEMLARLTAGEEVAWYDFVSAYEGRMYAYLYRLEGNAEDALDLTQEVFYRA
CCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
WRSIRTFRAGERVLPWLYQVARNTQIESHRRKQLQRFSLEEAREDVGFEVTSGARSPAQA
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHH
AESADAQDRVQHALMRLPQEYREAVVLRFVEDLPYDEIARIQGVAVGTAKSRVFRAKEQL
HHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHH
ADLLADVADVH
HHHHHHHHCCC
>Mature Secondary Structure 
TAEPDILTPEMLARLTAGEEVAWYDFVSAYEGRMYAYLYRLEGNAEDALDLTQEVFYRA
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHH
WRSIRTFRAGERVLPWLYQVARNTQIESHRRKQLQRFSLEEAREDVGFEVTSGARSPAQA
HHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHH
AESADAQDRVQHALMRLPQEYREAVVLRFVEDLPYDEIARIQGVAVGTAKSRVFRAKEQL
HHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHH
ADLLADVADVH
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]