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The map label for this gene is dtd

Identifier: 94985617

GI number: 94985617

Start: 1609418

End: 1609864

Strand: Reverse

Name: dtd

Synonym: Dgeo_1517

Alternate gene names: 94985617

Gene position: 1609864-1609418 (Counterclockwise)

Preceding gene: 94985618

Following gene: 94985616

Centisome position: 65.25

GC content: 68.68

Gene sequence:

>447_bases
ATGCGGGCGGTGTTGCAGCGGGTCACGCGGGCGACCTGCACCGTGGAAGGCCGCGTCACGGGCGCAACTGGTCCGGGCTT
GCTGATCCTGCTCGGCGTGGCGCCGGAGGACACGCCCGAGACCGCCTGGCGCCTGGCCGCGAAAATCGTGAAGCTGCGGG
TGTTTGCCGACGAGACCGGGAGGATGAACCGCAGCGTGCAGGACATCGGCGGCGGCATCCTGAGTATCAGCCAGTTCACC
CTGTATGCCGACACGCGCCGAGGCAACCGTCCGGGCTTCAGCGGGGCCGCCGCGCCCGAGCACGCGCGCGCGCTTTATGC
CGAATTCAACGCGGCCCTGCGCGCCCAGGGCGTCGCGGTGGGGGAGGGGGTCTTTGGCGCCCATATGATGCTTGACCTGA
CCAACGACGGTCCGGTGACGCTGTTTCTCGACACCGCAGAAAGCTAA

Upstream 100 bases:

>100_bases
AAGACGCGCGGCAACCTCGACTTCACCGAGGCGGAACTGCTGACGAACGCCATCGCCAGCCTGCACGCCCGCCTCACCCC
GTCAGATCTGGGGCATTGAC

Downstream 100 bases:

>100_bases
GGCTTTCACCTGTCCCTGCAGACGGCTCGCTATCCTGCGCCGCATGAGGTCCCGCCTGCCCCAGCGTTCTGTCCTGTTGC
TCGCCGTCACGCTTCTGTTG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MRAVLQRVTRATCTVEGRVTGATGPGLLILLGVAPEDTPETAWRLAAKIVKLRVFADETGRMNRSVQDIGGGILSISQFT
LYADTRRGNRPGFSGAAAPEHARALYAEFNAALRAQGVAVGEGVFGAHMMLDLTNDGPVTLFLDTAES

Sequences:

>Translated_148_residues
MRAVLQRVTRATCTVEGRVTGATGPGLLILLGVAPEDTPETAWRLAAKIVKLRVFADETGRMNRSVQDIGGGILSISQFT
LYADTRRGNRPGFSGAAAPEHARALYAEFNAALRAQGVAVGEGVFGAHMMLDLTNDGPVTLFLDTAES
>Mature_148_residues
MRAVLQRVTRATCTVEGRVTGATGPGLLILLGVAPEDTPETAWRLAAKIVKLRVFADETGRMNRSVQDIGGGILSISQFT
LYADTRRGNRPGFSGAAAPEHARALYAEFNAALRAQGVAVGEGVFGAHMMLDLTNDGPVTLFLDTAES

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=42.5675675675676, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=51.0489510489511, Blast_Score=145, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=43.046357615894, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=37.3333333333333, Blast_Score=115, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=40, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_DEIGD (Q1IY72)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_604981.1
- ProteinModelPortal:   Q1IY72
- SMR:   Q1IY72
- STRING:   Q1IY72
- GeneID:   4057403
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_1517
- NMPDR:   fig|68909.1.peg.1699
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q1IY72
- ProtClustDB:   PRK05273
- BioCyc:   DGEO319795:DGEO_1517-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15658; Mature: 15658

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLQRVTRATCTVEGRVTGATGPGLLILLGVAPEDTPETAWRLAAKIVKLRVFADETG
CHHHHHHHHHHHEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
RMNRSVQDIGGGILSISQFTLYADTRRGNRPGFSGAAAPEHARALYAEFNAALRAQGVAV
CCCCCHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
GEGVFGAHMMLDLTNDGPVTLFLDTAES
CCCCCCEEEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MRAVLQRVTRATCTVEGRVTGATGPGLLILLGVAPEDTPETAWRLAAKIVKLRVFADETG
CHHHHHHHHHHHEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
RMNRSVQDIGGGILSISQFTLYADTRRGNRPGFSGAAAPEHARALYAEFNAALRAQGVAV
CCCCCHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEE
GEGVFGAHMMLDLTNDGPVTLFLDTAES
CCCCCCEEEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA