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The map label for this gene is hisC2 [H]

Identifier: 94972338

GI number: 94972338

Start: 146501

End: 147361

Strand: Direct

Name: hisC2 [H]

Synonym: Dgeo_2875

Alternate gene names: 94972338

Gene position: 146501-147361 (Clockwise)

Preceding gene: 94971817

Following gene: 94972337

Centisome position: 25.52

GC content: 71.54

Gene sequence:

>861_bases
GTGCGCGCTCGGCTGGCCGCCTGGCACGGGGTCTCGCCGGATGAGGTGGCGCTGTCGGTGGGGGCTTCGGACCTGCTGCA
CCGCCTGGTGCGGGCCTTTCTTCTTGCGGGCGACACGCTGCTGAGTGTTTTGGCCCCATTCGGAGAACTGGCCCGTGCGG
CGGCGCTCGCCCGAGCACAGGTGGAGGTGCGGCGGGAAGCGCCCCGCTCGCTCGCGCCGGGGGTGCGCCTCGTGTATGTC
GGGCATCCCCACAATCCCAGCGGCCACGCGCACAGTGCCGCCGAACTCCAAGATCTCGCGGACCTGTGCGCCAAAACCGG
CGCCCTGTTGATCGTGGACGAGGCGTACGCCCCCTTCACCGCTGCCCCCACACCGCCCCGGCACCCGAATGTCGTCCGCG
TTCTGTCGCCCGGCAAGGCACACGGCCTGGTGGGGGTGCGGCCCGCCTATGCGCTCGCGGTCCCGGAGGTCGCCGCGCGG
CTGGACAATCTCGCGCCCGCCTGGCACCTGCCCGCTGGGACTGCGGCGGTCCTCGCGGCGTTGCCGGACGCCCAGAGCTT
TTTGGCTCAGACCCTGCCGCAGGTGGCCCGCAACGCTCGGGCACTTGCGGAGGAGCTGGCGCGGCTCGGCCCGGTGGACC
ATCACGGCACGCCCTACCTGACCCTGGAGGTGGGGAACGCGCCGCGCGTGGCTGCCGCCCTGCAGAGCAGCGGCTGCCAG
GTCCGCGACTGCACCAGCTACGGACAACCCGGCCGCATTCGCGTCGCCACCCGCCTTCCCGCCGAGAATGCGCGGTTGGT
GGCGGCGTTGCGGCAGATCCTGAAGGGAGAACACACGTTGAAGGAAGAACACTGTGGGTAA

Upstream 100 bases:

>100_bases
TTCAGCGTGAACGCCAACCCCTACGGCCCGAATCCACTGCTGGTCAGGGCGCTGCGGGACGCTGACCACGCCCACTATCN
CCGACCCGACCTACTGGGAG

Downstream 100 bases:

>100_bases
GGCCATCATGATTCAGGGCTGCACCAGCAGTGCAGGCAAGAGTTATCTGTGCGCCGCCCTGTGCCGCGCCCTTGCGAACG
AGGGCTACCGGGTCGCGCCC

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRARLAAWHGVSPDEVALSVGASDLLHRLVRAFLLAGDTLLSVLAPFGELARAAALARAQVEVRREAPRSLAPGVRLVYV
GHPHNPSGHAHSAAELQDLADLCAKTGALLIVDEAYAPFTAAPTPPRHPNVVRVLSPGKAHGLVGVRPAYALAVPEVAAR
LDNLAPAWHLPAGTAAVLAALPDAQSFLAQTLPQVARNARALAEELARLGPVDHHGTPYLTLEVGNAPRVAAALQSSGCQ
VRDCTSYGQPGRIRVATRLPAENARLVAALRQILKGEHTLKEEHCG

Sequences:

>Translated_286_residues
MRARLAAWHGVSPDEVALSVGASDLLHRLVRAFLLAGDTLLSVLAPFGELARAAALARAQVEVRREAPRSLAPGVRLVYV
GHPHNPSGHAHSAAELQDLADLCAKTGALLIVDEAYAPFTAAPTPPRHPNVVRVLSPGKAHGLVGVRPAYALAVPEVAAR
LDNLAPAWHLPAGTAAVLAALPDAQSFLAQTLPQVARNARALAEELARLGPVDHHGTPYLTLEVGNAPRVAAALQSSGCQ
VRDCTSYGQPGRIRVATRLPAENARLVAALRQILKGEHTLKEEHCG
>Mature_286_residues
MRARLAAWHGVSPDEVALSVGASDLLHRLVRAFLLAGDTLLSVLAPFGELARAAALARAQVEVRREAPRSLAPGVRLVYV
GHPHNPSGHAHSAAELQDLADLCAKTGALLIVDEAYAPFTAAPTPPRHPNVVRVLSPGKAHGLVGVRPAYALAVPEVAAR
LDNLAPAWHLPAGTAAVLAALPDAQSFLAQTLPQVARNARALAEELARLGPVDHHGTPYLTLEVGNAPRVAAALQSSGCQ
VRDCTSYGQPGRIRVATRLPAENARLVAALRQILKGEHTLKEEHCG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=292, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 30064; Mature: 30064

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARLAAWHGVSPDEVALSVGASDLLHRLVRAFLLAGDTLLSVLAPFGELARAAALARAQ
CCCCCCHHCCCCHHHHEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VEVRREAPRSLAPGVRLVYVGHPHNPSGHAHSAAELQDLADLCAKTGALLIVDEAYAPFT
HHHHHHCCHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCC
AAPTPPRHPNVVRVLSPGKAHGLVGVRPAYALAVPEVAARLDNLAPAWHLPAGTAAVLAA
CCCCCCCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LPDAQSFLAQTLPQVARNARALAEELARLGPVDHHGTPYLTLEVGNAPRVAAALQSSGCQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCC
VRDCTSYGQPGRIRVATRLPAENARLVAALRQILKGEHTLKEEHCG
EEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MRARLAAWHGVSPDEVALSVGASDLLHRLVRAFLLAGDTLLSVLAPFGELARAAALARAQ
CCCCCCHHCCCCHHHHEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VEVRREAPRSLAPGVRLVYVGHPHNPSGHAHSAAELQDLADLCAKTGALLIVDEAYAPFT
HHHHHHCCHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCC
AAPTPPRHPNVVRVLSPGKAHGLVGVRPAYALAVPEVAARLDNLAPAWHLPAGTAAVLAA
CCCCCCCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LPDAQSFLAQTLPQVARNARALAEELARLGPVDHHGTPYLTLEVGNAPRVAAALQSSGCQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCC
VRDCTSYGQPGRIRVATRLPAENARLVAALRQILKGEHTLKEEHCG
EEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA