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The map label for this gene is nixA [H]

Identifier: 94971822

GI number: 94971822

Start: 136257

End: 137267

Strand: Direct

Name: nixA [H]

Synonym: Dgeo_2353

Alternate gene names: 94971822

Gene position: 136257-137267 (Clockwise)

Preceding gene: 94971823

Following gene: 94971821

Centisome position: 23.73

GC content: 70.52

Gene sequence:

>1011_bases
ATGACGCGCTCTTCACCTGACGCCGCCCCCCGGGCCGACCTCGCCGCGCCGCTCACCCTGCGCCAAAGCGTGCTGCAGGG
CCTTCCCTACCTGCTGGTGGTGTTGCTGCTGCACGGGCTGGCCCTGGTCCTGTGGGTGCCCGCCGCCCTGCACGCGCCGC
TGCTGTGGGGCGTGGGTTTCACCGCCTACCTGTTCGGGCTGCGGCACGCCTGGGATGCCGACCACATCGCCGTGATCGAC
AACACCGTCCGCAAGCTGCTCACGCTGGGCCGCCCGGCCTACGGGGTGGGCCTGAGTTTCAGCCTGGGGCACTCGGCGGT
GGTGTTTCTGATGGCCGTCGCGGCGGCGATCGTCGGCAAGGCGCTGCTGGGTGCGCAGGAAGGCATCGGCGCTTTTGGGG
GCTGGGTGGGGCCGTTTGTGGCGGGGGCCTACCTCGTCACGGTGGCCGCCGTCAATCTGTCCTCGGCCCTGCAGATTCTG
CGGGCGGGGGATGAACCGGGGCACCAGCACAGTGGCCTGCTTGCGCGGCTGATCGCGCCCCTCACCCGGCTGGTGAGCTG
GCAGTGGCAGGTGCTGCCGCTGGGCTTCCTGATGGGTCTGGGCTTCGATACGGCCTCTGAGGTCGCGCTGCTGGCCCTGT
CGGGCACGGCAGCGCAGCAGGGGCTGAGCTGGGCGGCGATCCTCTCGCTGCCGCTGCTGTTTGCCGCCGGAATGACGCTG
CTCGACACCCTCGACGGCGTCGCCATGGCCCACGCCTACGGCTGGGCGCTGCACAACCCGCGCAGCAAACGCACCTATAA
CCTGCTGGTCACCGGGCTGTCGGGCGTGATTGCCCTGGTGATCGGCGTAGTCACGCTGGCGCAGTGGGCGGGGGAACACT
TCCCGGCTGCCGAGGCCTCTCTGGCGGCCCTGCAAGACGTGGACGTCTCCCCGCTGGGCTTCTGGTTGGCGGGCCTGACG
CTGCTCCTCTTTGTGGCCGCTCAGCTGTGGACACGGGCGCGCCGGGTGTGA

Upstream 100 bases:

>100_bases
GTGGACGCTCCCAACGAACTGATCTTTATCGGCTATCACGTCAGCCGCAAAAAGGTCACCGAAGCGCTCCAAAAGGCGCT
GCCGCAGCGGTGGGGTTGAG

Downstream 100 bases:

>100_bases
AGGAGGGTCCGTGACCGGAGCCGCATCCCGCTCGCCTGCTTCTCGGCAGAGGGTGACCCGTGCCGATGGCCGCACCATCA
ATGTGGTCCGCAAGCGCGGG

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTRSSPDAAPRADLAAPLTLRQSVLQGLPYLLVVLLLHGLALVLWVPAALHAPLLWGVGFTAYLFGLRHAWDADHIAVID
NTVRKLLTLGRPAYGVGLSFSLGHSAVVFLMAVAAAIVGKALLGAQEGIGAFGGWVGPFVAGAYLVTVAAVNLSSALQIL
RAGDEPGHQHSGLLARLIAPLTRLVSWQWQVLPLGFLMGLGFDTASEVALLALSGTAAQQGLSWAAILSLPLLFAAGMTL
LDTLDGVAMAHAYGWALHNPRSKRTYNLLVTGLSGVIALVIGVVTLAQWAGEHFPAAEASLAALQDVDVSPLGFWLAGLT
LLLFVAAQLWTRARRV

Sequences:

>Translated_336_residues
MTRSSPDAAPRADLAAPLTLRQSVLQGLPYLLVVLLLHGLALVLWVPAALHAPLLWGVGFTAYLFGLRHAWDADHIAVID
NTVRKLLTLGRPAYGVGLSFSLGHSAVVFLMAVAAAIVGKALLGAQEGIGAFGGWVGPFVAGAYLVTVAAVNLSSALQIL
RAGDEPGHQHSGLLARLIAPLTRLVSWQWQVLPLGFLMGLGFDTASEVALLALSGTAAQQGLSWAAILSLPLLFAAGMTL
LDTLDGVAMAHAYGWALHNPRSKRTYNLLVTGLSGVIALVIGVVTLAQWAGEHFPAAEASLAALQDVDVSPLGFWLAGLT
LLLFVAAQLWTRARRV
>Mature_335_residues
TRSSPDAAPRADLAAPLTLRQSVLQGLPYLLVVLLLHGLALVLWVPAALHAPLLWGVGFTAYLFGLRHAWDADHIAVIDN
TVRKLLTLGRPAYGVGLSFSLGHSAVVFLMAVAAAIVGKALLGAQEGIGAFGGWVGPFVAGAYLVTVAAVNLSSALQILR
AGDEPGHQHSGLLARLIAPLTRLVSWQWQVLPLGFLMGLGFDTASEVALLALSGTAAQQGLSWAAILSLPLLFAAGMTLL
DTLDGVAMAHAYGWALHNPRSKRTYNLLVTGLSGVIALVIGVVTLAQWAGEHFPAAEASLAALQDVDVSPLGFWLAGLTL
LLFVAAQLWTRARRV

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 35254; Mature: 35123

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSSPDAAPRADLAAPLTLRQSVLQGLPYLLVVLLLHGLALVLWVPAALHAPLLWGVGF
CCCCCCCCCCCCHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYLFGLRHAWDADHIAVIDNTVRKLLTLGRPAYGVGLSFSLGHSAVVFLMAVAAAIVGK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
ALLGAQEGIGAFGGWVGPFVAGAYLVTVAAVNLSSALQILRAGDEPGHQHSGLLARLIAP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LTRLVSWQWQVLPLGFLMGLGFDTASEVALLALSGTAAQQGLSWAAILSLPLLFAAGMTL
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHH
LDTLDGVAMAHAYGWALHNPRSKRTYNLLVTGLSGVIALVIGVVTLAQWAGEHFPAAEAS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LAALQDVDVSPLGFWLAGLTLLLFVAAQLWTRARRV
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRSSPDAAPRADLAAPLTLRQSVLQGLPYLLVVLLLHGLALVLWVPAALHAPLLWGVGF
CCCCCCCCCCCHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]