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The map label for this gene is mocR [H]

Identifier: 94313243

GI number: 94313243

Start: 912409

End: 913923

Strand: Reverse

Name: mocR [H]

Synonym: Rmet_4318

Alternate gene names: 94313243

Gene position: 913923-912409 (Counterclockwise)

Preceding gene: 94313252

Following gene: 94313242

Centisome position: 35.42

GC content: 62.51

Gene sequence:

>1515_bases
GTGTGGTTTCGGGCCGCGTACTCCTCTTCAACGCCGCAACTAGCCCTAGAATCCGGCGGAATCGCCATTCGCGCCTACAA
GATGAACGCCCACATCAAGCTCCGCGGCCGCCGTGACCTGGCTGGTCAGATCTATCGACAGATTCGCGCCAGCATCGTCG
ACGGACGGCTCGCGCCAGGAGAACGCCTACCCTCCACACGCACGCTGGCGTCGGAGCTCGACGTCTCCAGAAAGACGACG
CTCGATGTGTTCGAGCGGTTGATCGGCGAAGGCTATCTGCGGTCTCGTACCGGCGACGGAACCTTCGTGTCCGATGAGAT
GACGCGCCTGGCGCCTACGCCGCCGCGCGAGCGGATCGTGCAGGCCACTGGAGCGGTGTGGGAAACGCTACCCGAGGCAT
TGCCCGCGAGCCGGAAAGACATGCCGGCACGCTTCGATTTCGTAGGCGGCGTCACCGACAAGCGCCTGTTTCCGTTCGAC
AAATGGCGCAAATGCGTTAGCCACGCGCTGCGCATCCAGGCGCGCGGAAACGGTTCTTATCACGACCCATCGGGCGATCA
GGAACTGCGTCTGGCCATCTCGCGTTATCTGGCTTCGAGCCGCGCGGTGGTCAGCAACTGGCAGGACGTCATCGTTACCA
ACGGAGCGCAACAGGCCATTGAACTGCTGGCGCGCGCGGTCATCCGGCCAGGCGATGTGATCGCGGTGGAAGATCCCGGC
TATCCGCCCGCGCGAAGCGTCTTTACCGCGGCGGGCGCCAGGGTGATCGACGTACCGGTCGACAAGGACGGTCTGCGGGT
GGATGCCCTGCCGTCGAAGGCGAGGATGGTCTATGTCACGCCGTCCCACCAGTTTCCGCTAGGCATGCCGATGACGCTTG
AGCGTCGCCTTGCCCTGCTCGAATGGGCGCACCGGCGAGGCGCTCTCGTGATCGAGGATGACTATGACGGCGAATACCGC
TTCGAGGGCAGACCGATGGAATCATTGAAGAGTCTCGACAACGCCGGAGTCGTTGCATACGTTGGCACGTTTTCGAAGAC
CATCTTTCCGGAACTGCGGATTGGCTACATGATTCCGCCGTCGTCCCTGGCGGCCACGCTTCGAAAGGCCAAACAGGTCA
GTGACTGGCATAGCAGCACCCTGATGCAGACCGCATTGGGCAAGTTCATGCTGGACGGATACTTCGCCAAGCATCTGCGC
CACATGCACCGGGAGTACGCCAGGCGACGCGCGACGCTGCTGGAGTACCTGCAGGGTGACCTGGCCGACGTCTTCACGCC
GCTACCGTCCGTGGCCGGCATCCATCTGGTCGCGATACTGGCCGACGATACAAACGAAGCAGACATCATTGCCCGGGCCA
ACCAGGCATCGGTGGGCCTGTACGGCATTTCCAGGATGTTCAATACCCAGCCTTCGCGGCAAGGCATTCTGTTTGGCTAC
GGCGGCATCGGTGTGGACGATATACGGAGTGGCCTGACCCAACTCGGTGAAACACTTCGCGCCACCCGGCGTTGA

Upstream 100 bases:

>100_bases
GAGCGCCCTCGCTTCGGCCAATTTTGTATCGATTGCTACGAAATTATTATAGATCGATCGATACAAAACACAACGAACAC
GCCGAGACCCCACATCGCCA

Downstream 100 bases:

>100_bases
TGGCGTGCGTCGAAAAATTGGTCACCTCAAAATAGCCATAAATCGGTACTAAAAGGTCACCACTTCATTGCCTAAGCTTG
CGTCTGAGGCGTGCCAGCCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MWFRAAYSSSTPQLALESGGIAIRAYKMNAHIKLRGRRDLAGQIYRQIRASIVDGRLAPGERLPSTRTLASELDVSRKTT
LDVFERLIGEGYLRSRTGDGTFVSDEMTRLAPTPPRERIVQATGAVWETLPEALPASRKDMPARFDFVGGVTDKRLFPFD
KWRKCVSHALRIQARGNGSYHDPSGDQELRLAISRYLASSRAVVSNWQDVIVTNGAQQAIELLARAVIRPGDVIAVEDPG
YPPARSVFTAAGARVIDVPVDKDGLRVDALPSKARMVYVTPSHQFPLGMPMTLERRLALLEWAHRRGALVIEDDYDGEYR
FEGRPMESLKSLDNAGVVAYVGTFSKTIFPELRIGYMIPPSSLAATLRKAKQVSDWHSSTLMQTALGKFMLDGYFAKHLR
HMHREYARRRATLLEYLQGDLADVFTPLPSVAGIHLVAILADDTNEADIIARANQASVGLYGISRMFNTQPSRQGILFGY
GGIGVDDIRSGLTQLGETLRATRR

Sequences:

>Translated_504_residues
MWFRAAYSSSTPQLALESGGIAIRAYKMNAHIKLRGRRDLAGQIYRQIRASIVDGRLAPGERLPSTRTLASELDVSRKTT
LDVFERLIGEGYLRSRTGDGTFVSDEMTRLAPTPPRERIVQATGAVWETLPEALPASRKDMPARFDFVGGVTDKRLFPFD
KWRKCVSHALRIQARGNGSYHDPSGDQELRLAISRYLASSRAVVSNWQDVIVTNGAQQAIELLARAVIRPGDVIAVEDPG
YPPARSVFTAAGARVIDVPVDKDGLRVDALPSKARMVYVTPSHQFPLGMPMTLERRLALLEWAHRRGALVIEDDYDGEYR
FEGRPMESLKSLDNAGVVAYVGTFSKTIFPELRIGYMIPPSSLAATLRKAKQVSDWHSSTLMQTALGKFMLDGYFAKHLR
HMHREYARRRATLLEYLQGDLADVFTPLPSVAGIHLVAILADDTNEADIIARANQASVGLYGISRMFNTQPSRQGILFGY
GGIGVDDIRSGLTQLGETLRATRR
>Mature_504_residues
MWFRAAYSSSTPQLALESGGIAIRAYKMNAHIKLRGRRDLAGQIYRQIRASIVDGRLAPGERLPSTRTLASELDVSRKTT
LDVFERLIGEGYLRSRTGDGTFVSDEMTRLAPTPPRERIVQATGAVWETLPEALPASRKDMPARFDFVGGVTDKRLFPFD
KWRKCVSHALRIQARGNGSYHDPSGDQELRLAISRYLASSRAVVSNWQDVIVTNGAQQAIELLARAVIRPGDVIAVEDPG
YPPARSVFTAAGARVIDVPVDKDGLRVDALPSKARMVYVTPSHQFPLGMPMTLERRLALLEWAHRRGALVIEDDYDGEYR
FEGRPMESLKSLDNAGVVAYVGTFSKTIFPELRIGYMIPPSSLAATLRKAKQVSDWHSSTLMQTALGKFMLDGYFAKHLR
HMHREYARRRATLLEYLQGDLADVFTPLPSVAGIHLVAILADDTNEADIIARANQASVGLYGISRMFNTQPSRQGILFGY
GGIGVDDIRSGLTQLGETLRATRR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=226, Percent_Identity=27.4336283185841, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI33469970, Length=226, Percent_Identity=27.4336283185841, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1790797, Length=373, Percent_Identity=28.1501340482574, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787710, Length=396, Percent_Identity=27.5252525252525, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55885; Mature: 55885

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFRAAYSSSTPQLALESGGIAIRAYKMNAHIKLRGRRDLAGQIYRQIRASIVDGRLAPG
CCEECCCCCCCCCEEEECCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
ERLPSTRTLASELDVSRKTTLDVFERLIGEGYLRSRTGDGTFVSDEMTRLAPTPPRERIV
CCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCEECCHHHHCCCCCHHHHHH
QATGAVWETLPEALPASRKDMPARFDFVGGVTDKRLFPFDKWRKCVSHALRIQARGNGSY
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCCC
HDPSGDQELRLAISRYLASSRAVVSNWQDVIVTNGAQQAIELLARAVIRPGDVIAVEDPG
CCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCC
YPPARSVFTAAGARVIDVPVDKDGLRVDALPSKARMVYVTPSHQFPLGMPMTLERRLALL
CCCHHHHHHHCCCEEEEECCCCCCCEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
EWAHRRGALVIEDDYDGEYRFEGRPMESLKSLDNAGVVAYVGTFSKTIFPELRIGYMIPP
HHHHHCCCEEEECCCCCCEEECCCCHHHHHCCCCCCEEEEECHHHHHHCCCCEEEEEECC
SSLAATLRKAKQVSDWHSSTLMQTALGKFMLDGYFAKHLRHMHREYARRRATLLEYLQGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADVFTPLPSVAGIHLVAILADDTNEADIIARANQASVGLYGISRMFNTQPSRQGILFGY
HHHHHHCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEE
GGIGVDDIRSGLTQLGETLRATRR
CCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWFRAAYSSSTPQLALESGGIAIRAYKMNAHIKLRGRRDLAGQIYRQIRASIVDGRLAPG
CCEECCCCCCCCCEEEECCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
ERLPSTRTLASELDVSRKTTLDVFERLIGEGYLRSRTGDGTFVSDEMTRLAPTPPRERIV
CCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCEECCHHHHCCCCCHHHHHH
QATGAVWETLPEALPASRKDMPARFDFVGGVTDKRLFPFDKWRKCVSHALRIQARGNGSY
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCCC
HDPSGDQELRLAISRYLASSRAVVSNWQDVIVTNGAQQAIELLARAVIRPGDVIAVEDPG
CCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCEEEECCCC
YPPARSVFTAAGARVIDVPVDKDGLRVDALPSKARMVYVTPSHQFPLGMPMTLERRLALL
CCCHHHHHHHCCCEEEEECCCCCCCEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
EWAHRRGALVIEDDYDGEYRFEGRPMESLKSLDNAGVVAYVGTFSKTIFPELRIGYMIPP
HHHHHCCCEEEECCCCCCEEECCCCHHHHHCCCCCCEEEEECHHHHHHCCCCEEEEEECC
SSLAATLRKAKQVSDWHSSTLMQTALGKFMLDGYFAKHLRHMHREYARRRATLLEYLQGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADVFTPLPSVAGIHLVAILADDTNEADIIARANQASVGLYGISRMFNTQPSRQGILFGY
HHHHHHCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEE
GGIGVDDIRSGLTQLGETLRATRR
CCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]