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The map label for this gene is 93006940

Identifier: 93006940

GI number: 93006940

Start: 2589573

End: 2590490

Strand: Direct

Name: 93006940

Synonym: Pcryo_2116

Alternate gene names: NA

Gene position: 2589573-2590490 (Clockwise)

Preceding gene: 93006939

Following gene: 93006943

Centisome position: 84.63

GC content: 43.03

Gene sequence:

>918_bases
ATGTTAAAAATTGCCTACTCTGATATTTTTCGTTATTCAGTACCCGAAAAACATCGTTTTCCGATGCAAAAATACACTAT
GATTCCTGAGCGCTTATTAGCGGAAAAGACTATTAGTGCGAATAACTTTTTTGCGCCCACACGCTTAAGCGAAGATGAAA
TCTTAACGACGCATACTGCTGATTATTGGTATCAGCTTAAGACCCAAACGCTACCAAGAAAAGAAGCGCGAGCGATCGGC
TTTGAGATGACGCCTGAGTTAGTAGAGCGTGGGCGCTATATTGCCCATGCGACTTATGAATGTGCGCTTTATGCTCAGCA
ATATGGCGTGGCGATGAATGTTGCCGGCGGTACGCACCATGCGTTTTCTGATCATGGCGAGGGCTTTTGCGTGTTTAATG
ATGTCTGTATTGCGAGTAATTTATTATTAAATCGTGGACAGGCGCAAAAGATTTTGGTGGTCGATTTGGATGTGCATCAA
GGCAACGGCAATGCCAGTATCATGGCGAATGAGCCACGCGTTTTTATCTTTAGTATGCATGGCGCAAAGAACTATCCGTT
TCGTAAACAAGTATCAGACTTAGATATTGAGCTAGATAACGATACTGGTGATGAGCAATATTTACAGATATTAGAAGACA
CGCTACCGCGCTTAATTAGCGACGTTGCACCAGATATGATCTTTTATCAGTCTGCTGTCGATGTACTGGCGACCGATAAG
TTGGGAAAACTTGGGCTGACGATAGAAGGTTGTAAGGCGCGTGATGAATATGTGTTACGCCAAGCAAAAGCCGCTAAAAT
TCCTATCGCTATCGTGATGGGTGGCGGCTATTCAGAAGATATTGAAGATGTGGTTGAAGCGCACTGCAATACGTTTCGTT
TGGCGCAACAGATATTTTTTGATGAAATAACAGAATAA

Upstream 100 bases:

>100_bases
AGTGAGACTGGATTGTTTTTCCAGTGAAACCATCAGCTCAAACTTACTATGTTAGACAACCCTCTACTCAGAAAGCCTTT
AATACGATATTAGAAATACT

Downstream 100 bases:

>100_bases
CACGCGCATAAAATAGCATTTTAACAGCCAGCTGCCTCGCGAACTAGTTTATAAAAACGCTACAATCCCCTGCCAGCCGA
CACGAATACCAAGCACTGTA

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLKIAYSDIFRYSVPEKHRFPMQKYTMIPERLLAEKTISANNFFAPTRLSEDEILTTHTADYWYQLKTQTLPRKEARAIG
FEMTPELVERGRYIAHATYECALYAQQYGVAMNVAGGTHHAFSDHGEGFCVFNDVCIASNLLLNRGQAQKILVVDLDVHQ
GNGNASIMANEPRVFIFSMHGAKNYPFRKQVSDLDIELDNDTGDEQYLQILEDTLPRLISDVAPDMIFYQSAVDVLATDK
LGKLGLTIEGCKARDEYVLRQAKAAKIPIAIVMGGGYSEDIEDVVEAHCNTFRLAQQIFFDEITE

Sequences:

>Translated_305_residues
MLKIAYSDIFRYSVPEKHRFPMQKYTMIPERLLAEKTISANNFFAPTRLSEDEILTTHTADYWYQLKTQTLPRKEARAIG
FEMTPELVERGRYIAHATYECALYAQQYGVAMNVAGGTHHAFSDHGEGFCVFNDVCIASNLLLNRGQAQKILVVDLDVHQ
GNGNASIMANEPRVFIFSMHGAKNYPFRKQVSDLDIELDNDTGDEQYLQILEDTLPRLISDVAPDMIFYQSAVDVLATDK
LGKLGLTIEGCKARDEYVLRQAKAAKIPIAIVMGGGYSEDIEDVVEAHCNTFRLAQQIFFDEITE
>Mature_305_residues
MLKIAYSDIFRYSVPEKHRFPMQKYTMIPERLLAEKTISANNFFAPTRLSEDEILTTHTADYWYQLKTQTLPRKEARAIG
FEMTPELVERGRYIAHATYECALYAQQYGVAMNVAGGTHHAFSDHGEGFCVFNDVCIASNLLLNRGQAQKILVVDLDVHQ
GNGNASIMANEPRVFIFSMHGAKNYPFRKQVSDLDIELDNDTGDEQYLQILEDTLPRLISDVAPDMIFYQSAVDVLATDK
LGKLGLTIEGCKARDEYVLRQAKAAKIPIAIVMGGGYSEDIEDVVEAHCNTFRLAQQIFFDEITE

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI209862883, Length=283, Percent_Identity=30.0353356890459, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI217272877, Length=294, Percent_Identity=30.6122448979592, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI13128860, Length=204, Percent_Identity=30.8823529411765, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI13128862, Length=181, Percent_Identity=29.8342541436464, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI8923769, Length=255, Percent_Identity=27.0588235294118, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI293336691, Length=159, Percent_Identity=30.188679245283, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI13128864, Length=261, Percent_Identity=25.2873563218391, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20070354, Length=277, Percent_Identity=25.9927797833935, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193207430, Length=291, Percent_Identity=29.8969072164948, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17508561, Length=288, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17537347, Length=249, Percent_Identity=28.5140562248996, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540332, Length=204, Percent_Identity=30.8823529411765, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193206283, Length=204, Percent_Identity=30.8823529411765, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534739, Length=292, Percent_Identity=25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540334, Length=204, Percent_Identity=30.8823529411765, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561978, Length=202, Percent_Identity=27.2277227722772, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25154020, Length=184, Percent_Identity=27.7173913043478, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25154022, Length=184, Percent_Identity=27.7173913043478, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321244, Length=286, Percent_Identity=26.5734265734266, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323999, Length=204, Percent_Identity=27.9411764705882, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24649807, Length=288, Percent_Identity=30.9027777777778, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24644244, Length=297, Percent_Identity=23.9057239057239, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281360899, Length=292, Percent_Identity=27.0547945205479, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24642142, Length=292, Percent_Identity=27.0547945205479, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642146, Length=292, Percent_Identity=27.0547945205479, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642144, Length=292, Percent_Identity=27.0547945205479, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24657891, Length=294, Percent_Identity=24.8299319727891, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34450; Mature: 34450

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIAYSDIFRYSVPEKHRFPMQKYTMIPERLLAEKTISANNFFAPTRLSEDEILTTHTA
CEEEEEHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
DYWYQLKTQTLPRKEARAIGFEMTPELVERGRYIAHATYECALYAQQYGVAMNVAGGTHH
CCEEEEECCCCCCHHHHHCCCCCCHHHHHCCCEEEEEHHHHEEEHHHCCEEEEECCCCCC
AFSDHGEGFCVFNDVCIASNLLLNRGQAQKILVVDLDVHQGNGNASIMANEPRVFIFSMH
CCCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEEECCCEEEEEEEC
GAKNYPFRKQVSDLDIELDNDTGDEQYLQILEDTLPRLISDVAPDMIFYQSAVDVLATDK
CCCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
LGKLGLTIEGCKARDEYVLRQAKAAKIPIAIVMGGGYSEDIEDVVEAHCNTFRLAQQIFF
CCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DEITE
HHHCC
>Mature Secondary Structure
MLKIAYSDIFRYSVPEKHRFPMQKYTMIPERLLAEKTISANNFFAPTRLSEDEILTTHTA
CEEEEEHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
DYWYQLKTQTLPRKEARAIGFEMTPELVERGRYIAHATYECALYAQQYGVAMNVAGGTHH
CCEEEEECCCCCCHHHHHCCCCCCHHHHHCCCEEEEEHHHHEEEHHHCCEEEEECCCCCC
AFSDHGEGFCVFNDVCIASNLLLNRGQAQKILVVDLDVHQGNGNASIMANEPRVFIFSMH
CCCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEEECCCEEEEEEEC
GAKNYPFRKQVSDLDIELDNDTGDEQYLQILEDTLPRLISDVAPDMIFYQSAVDVLATDK
CCCCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
LGKLGLTIEGCKARDEYVLRQAKAAKIPIAIVMGGGYSEDIEDVVEAHCNTFRLAQQIFF
CCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DEITE
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]