Click here to switch to the map view.

The map label for this gene is truD [H]

Identifier: 93006795

GI number: 93006795

Start: 2431067

End: 2432242

Strand: Direct

Name: truD [H]

Synonym: Pcryo_1971

Alternate gene names: 93006795

Gene position: 2431067-2432242 (Clockwise)

Preceding gene: 93006792

Following gene: 93006798

Centisome position: 79.45

GC content: 47.96

Gene sequence:

>1176_bases
ATGACTGTTCAAGACCATGATATTACCGCTGCTACTGATACTGCCAATTTACCGCAGCCGATACAGCCGCTGTTAAAGCA
TGCTACTTACAAGGCTCATACCACGGATTTTATTGTTAACGAGTTGCTACCATTAGAGTTCACCGGTGAGGGTGAGCATC
TCTGGCTACATATCCAAAAGTCAGGGATGAACACGGCGTATCTTGCCAAATTATTGTCCGAATGGGCGGATATTCCTTTA
CGTGATGTCGGCTTCTCAGGACTGAAAGACCGTCATGCGCTAACAACGCAGTGGTTTAGCTTGCGCATACCAAAGAAGCA
ATTACCAGACTCTGAGTTTGCGCCCGTAGATATCGGTGCTAATGAGTCAATCACTATCCTTGAGCAGCAATGGCACAATA
AAAAGCTCAATCGTGGCACGCACCGCGCCAATCAATTTATTATTACCTTGCGTGATATTGAATTTGTAGGCTTTGATACA
CCATCACCATCATCTGAACAGCTCTTGTCTGTTAAGCAAGCCGTCGAGCAGCACTTAGTGATTATTGGTCAAAGTGGCGT
GCCCAATTATTTTGGGCCGCAGCGCTTTGGTCGCAGTGGCAACAATATTAGAGAAGCATTGTCGTTGTTTGCGCGTCCTG
TACCTGAGGCCCGTCCGCCGTCTAATAAAGGCAAACGTAAACGCGTGCCACGTGAGCAAAACACCATGGAGCTGTCGGCG
GCACGCAGTTTGATATTTAATGAGATATTGGCAGCACGTGTCCGTGATGGCAGCTGGAACCACGGACTTGCAGGTGAAGT
ATTTAATCTAGATGGCTCAGGCTCGATATTTGCAAGCGACGAGATAGACGATACCTTACGAGCCCGTCTTGAATCAGGCG
ATATCCATCCGACCGCCGTGCTGTGGGGCACAGGTAATGAGAAGGTCAGCGGCAAAGCGGCAGCCATGGAAGCGGACACC
GTAGCGCATAGTCCATTGTTAACACAGCTAGCCACAGGTCTAGAGCAGCGTGATATCAAGGCGCAAAGGCGAGCACTACG
ATTACCTATTGAAGCATTAAGCTGGGAATGGCAGGATACAGAAGGTAGTCAGATACTAATCTTAAACTTTACTTTGACGA
CCGGTAGCTTTGCGACCAGCGTATTAGCAAGTTTGGTACAAGAATTAAATACCTAG

Upstream 100 bases:

>100_bases
TTCACTTATGCTGTTCTTTTGTATATTGACCACGTTGCAAAACGTAATGACTGCTTTTTTAATCCCTATTAATGTTCTAT
AAAACGTAAAAGACTATCTT

Downstream 100 bases:

>100_bases
ACATTATCTATGTCATAACCGGTTAAGGACCTAAAAGGTTAAAGTACTGATTTATTTGCTAGCGGTATAAAATGAGATAA
CCGTGCTATTTTCTGCTGCT

Product: pseudouridylate synthase

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTVQDHDITAATDTANLPQPIQPLLKHATYKAHTTDFIVNELLPLEFTGEGEHLWLHIQKSGMNTAYLAKLLSEWADIPL
RDVGFSGLKDRHALTTQWFSLRIPKKQLPDSEFAPVDIGANESITILEQQWHNKKLNRGTHRANQFIITLRDIEFVGFDT
PSPSSEQLLSVKQAVEQHLVIIGQSGVPNYFGPQRFGRSGNNIREALSLFARPVPEARPPSNKGKRKRVPREQNTMELSA
ARSLIFNEILAARVRDGSWNHGLAGEVFNLDGSGSIFASDEIDDTLRARLESGDIHPTAVLWGTGNEKVSGKAAAMEADT
VAHSPLLTQLATGLEQRDIKAQRRALRLPIEALSWEWQDTEGSQILILNFTLTTGSFATSVLASLVQELNT

Sequences:

>Translated_391_residues
MTVQDHDITAATDTANLPQPIQPLLKHATYKAHTTDFIVNELLPLEFTGEGEHLWLHIQKSGMNTAYLAKLLSEWADIPL
RDVGFSGLKDRHALTTQWFSLRIPKKQLPDSEFAPVDIGANESITILEQQWHNKKLNRGTHRANQFIITLRDIEFVGFDT
PSPSSEQLLSVKQAVEQHLVIIGQSGVPNYFGPQRFGRSGNNIREALSLFARPVPEARPPSNKGKRKRVPREQNTMELSA
ARSLIFNEILAARVRDGSWNHGLAGEVFNLDGSGSIFASDEIDDTLRARLESGDIHPTAVLWGTGNEKVSGKAAAMEADT
VAHSPLLTQLATGLEQRDIKAQRRALRLPIEALSWEWQDTEGSQILILNFTLTTGSFATSVLASLVQELNT
>Mature_390_residues
TVQDHDITAATDTANLPQPIQPLLKHATYKAHTTDFIVNELLPLEFTGEGEHLWLHIQKSGMNTAYLAKLLSEWADIPLR
DVGFSGLKDRHALTTQWFSLRIPKKQLPDSEFAPVDIGANESITILEQQWHNKKLNRGTHRANQFIITLRDIEFVGFDTP
SPSSEQLLSVKQAVEQHLVIIGQSGVPNYFGPQRFGRSGNNIREALSLFARPVPEARPPSNKGKRKRVPREQNTMELSAA
RSLIFNEILAARVRDGSWNHGLAGEVFNLDGSGSIFASDEIDDTLRARLESGDIHPTAVLWGTGNEKVSGKAAAMEADTV
AHSPLLTQLATGLEQRDIKAQRRALRLPIEALSWEWQDTEGSQILILNFTLTTGSFATSVLASLVQELNT

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=358, Percent_Identity=36.3128491620112, Blast_Score=184, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 43344; Mature: 43213

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQDHDITAATDTANLPQPIQPLLKHATYKAHTTDFIVNELLPLEFTGEGEHLWLHIQK
CCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCCEEEEEEEC
SGMNTAYLAKLLSEWADIPLRDVGFSGLKDRHALTTQWFSLRIPKKQLPDSEFAPVDIGA
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHEEHEEEECCHHHCCCCCCCEEECCC
NESITILEQQWHNKKLNRGTHRANQFIITLRDIEFVGFDTPSPSSEQLLSVKQAVEQHLV
CCCEEEEHHHHHCHHHHCCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCEEE
IIGQSGVPNYFGPQRFGRSGNNIREALSLFARPVPEARPPSNKGKRKRVPREQNTMELSA
EEECCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHH
ARSLIFNEILAARVRDGSWNHGLAGEVFNLDGSGSIFASDEIDDTLRARLESGDIHPTAV
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECCCCCHHHHHHHHCCCCCCEEE
LWGTGNEKVSGKAAAMEADTVAHSPLLTQLATGLEQRDIKAQRRALRLPIEALSWEWQDT
EECCCCCCCCCCHHHEEHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCCEECCC
EGSQILILNFTLTTGSFATSVLASLVQELNT
CCCEEEEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVQDHDITAATDTANLPQPIQPLLKHATYKAHTTDFIVNELLPLEFTGEGEHLWLHIQK
CCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCCEEEEEEEC
SGMNTAYLAKLLSEWADIPLRDVGFSGLKDRHALTTQWFSLRIPKKQLPDSEFAPVDIGA
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHEEHEEEECCHHHCCCCCCCEEECCC
NESITILEQQWHNKKLNRGTHRANQFIITLRDIEFVGFDTPSPSSEQLLSVKQAVEQHLV
CCCEEEEHHHHHCHHHHCCCCCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCEEE
IIGQSGVPNYFGPQRFGRSGNNIREALSLFARPVPEARPPSNKGKRKRVPREQNTMELSA
EEECCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCHHHHHH
ARSLIFNEILAARVRDGSWNHGLAGEVFNLDGSGSIFASDEIDDTLRARLESGDIHPTAV
HHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECCCCCHHHHHHHHCCCCCCEEE
LWGTGNEKVSGKAAAMEADTVAHSPLLTQLATGLEQRDIKAQRRALRLPIEALSWEWQDT
EECCCCCCCCCCHHHEEHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCCEECCC
EGSQILILNFTLTTGSFATSVLASLVQELNT
CCCEEEEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA