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The map label for this gene is hutI [H]

Identifier: 93006758

GI number: 93006758

Start: 2386826

End: 2388163

Strand: Direct

Name: hutI [H]

Synonym: Pcryo_1934

Alternate gene names: 93006758

Gene position: 2386826-2388163 (Clockwise)

Preceding gene: 93006757

Following gene: 93006761

Centisome position: 78.0

GC content: 44.62

Gene sequence:

>1338_bases
ATGAACAACTCTAGCGAACAGATACTTGACGACTCTATCAATACTACCGATGCTATGGATGCCTTAACAACGTTTGACCA
TATTATTATCAATGCCAATCTTGCGACTTTTTCAGCGCAATATGGTTTCGATACTTATGCTGACAATAAAGACAGTATAT
CCGCAGCCGCAAAAAGCACGCCTTATGGTCAATTAGAAAACGCTGCTATCGGCATCAAAGACAGCAAAATTGCATGGATT
GGGGCGCATACGCAAATAACACCCTATCTCACGCATTATCAAAGTCAGCAAATCACTGACGCTGATGGTCATTGGATAAC
GCCTGGATTGATAGATTGCCATACTCATATCGTCTATGGCGGCAACCGCAGCAATGAGTTTGAAGCGCGTCTACACGGTG
CCAACTATCAAGATATTGCTGCCCAAGGTGGCGGTATTGTCTCAACAGTTCGTTCCACTCGCGAAGCCAATATCGAAGAA
TTGTTTGCACAAAGTGAAAAACGCCTGCTGGCGCTTGTCAAAGAAGGTGTGACCAGTATCGAGATTAAATCTGGTTATGG
ACTAGACTTAAAAACTGAACGTAAAATGCTAAAAGTTGCCCGCGCACTCGGTGACAAACACAACATTCATGTCAGCACCA
CTTATTTAGCTGCTCATGCCCTACCACCTGAATACAAAGATCGTGTCGATGACTATATTGAGCAAGTTTGCCAGTGGTTA
CCAATCTTGCATAGCGAGGGCTTGGTCGATGCAGTCGATGGCTTTTGTGAAAATATCGCTTTTACTACTGAGCAGATTAA
GCGCGTCTTTGAAGTCGCACGCTCATTAAACTTACCGGTGAAACTGCATTCTGAACAACTATCAAATATAGGCGCTAGCG
CCTTAGTTGCTGAATATCAAGGATTATCAAGCGACCATCTTGAGCACTTAGTAGAAGACGATATCAAAAAAATGGCAACA
AGCAACACCGTTGCTGTGCTGTTGCCAGGCGCGTTTTATACCCTACGTGATACCAAGTTGCCACCGATCGAAGAACTGCG
TAAACATCAAGTACCAATGGCAATTTCGACTGACTGTAATCCAGGTACCTCACCGCTGACCTCACTGCTATTAGCGATGA
ATATGGGCTGTACGCTATTTTATATGACCCCTGAAGAAGTATTGGCAGGGGCAACGGTTCATGCTGCTCAAGCGTTAGGT
CTAGCTCATAAAGGGCGTATAGAAGTGGGCTGTGATGCGGATTTGGCGCTTTGGGATATCACTCGCCCTGCTGATTTAGC
CTATCAAATGGGGCTAAATCCTATTGAAGGTATTATGATCAAAGGTGCATGGCGTTAA

Upstream 100 bases:

>100_bases
AGCAGCATTTACTGAATTTATAGATAAAGGTTTATAAGTTTAACTTTAGAAATGAATTTTATATATTTACCTGATTATCA
GTGTTAAGCAGGAGCTTATT

Downstream 100 bases:

>100_bases
ACTTTACCACTCGTGTTTGACCACGCTCTTTTAAATCCTAAAAAGCCCTAATCAATGAATGATTGGGGCTTTTGGTTTAT
GAAAAGAACTTATGTCTTAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNNSSEQILDDSINTTDAMDALTTFDHIIINANLATFSAQYGFDTYADNKDSISAAAKSTPYGQLENAAIGIKDSKIAWI
GAHTQITPYLTHYQSQQITDADGHWITPGLIDCHTHIVYGGNRSNEFEARLHGANYQDIAAQGGGIVSTVRSTREANIEE
LFAQSEKRLLALVKEGVTSIEIKSGYGLDLKTERKMLKVARALGDKHNIHVSTTYLAAHALPPEYKDRVDDYIEQVCQWL
PILHSEGLVDAVDGFCENIAFTTEQIKRVFEVARSLNLPVKLHSEQLSNIGASALVAEYQGLSSDHLEHLVEDDIKKMAT
SNTVAVLLPGAFYTLRDTKLPPIEELRKHQVPMAISTDCNPGTSPLTSLLLAMNMGCTLFYMTPEEVLAGATVHAAQALG
LAHKGRIEVGCDADLALWDITRPADLAYQMGLNPIEGIMIKGAWR

Sequences:

>Translated_445_residues
MNNSSEQILDDSINTTDAMDALTTFDHIIINANLATFSAQYGFDTYADNKDSISAAAKSTPYGQLENAAIGIKDSKIAWI
GAHTQITPYLTHYQSQQITDADGHWITPGLIDCHTHIVYGGNRSNEFEARLHGANYQDIAAQGGGIVSTVRSTREANIEE
LFAQSEKRLLALVKEGVTSIEIKSGYGLDLKTERKMLKVARALGDKHNIHVSTTYLAAHALPPEYKDRVDDYIEQVCQWL
PILHSEGLVDAVDGFCENIAFTTEQIKRVFEVARSLNLPVKLHSEQLSNIGASALVAEYQGLSSDHLEHLVEDDIKKMAT
SNTVAVLLPGAFYTLRDTKLPPIEELRKHQVPMAISTDCNPGTSPLTSLLLAMNMGCTLFYMTPEEVLAGATVHAAQALG
LAHKGRIEVGCDADLALWDITRPADLAYQMGLNPIEGIMIKGAWR
>Mature_445_residues
MNNSSEQILDDSINTTDAMDALTTFDHIIINANLATFSAQYGFDTYADNKDSISAAAKSTPYGQLENAAIGIKDSKIAWI
GAHTQITPYLTHYQSQQITDADGHWITPGLIDCHTHIVYGGNRSNEFEARLHGANYQDIAAQGGGIVSTVRSTREANIEE
LFAQSEKRLLALVKEGVTSIEIKSGYGLDLKTERKMLKVARALGDKHNIHVSTTYLAAHALPPEYKDRVDDYIEQVCQWL
PILHSEGLVDAVDGFCENIAFTTEQIKRVFEVARSLNLPVKLHSEQLSNIGASALVAEYQGLSSDHLEHLVEDDIKKMAT
SNTVAVLLPGAFYTLRDTKLPPIEELRKHQVPMAISTDCNPGTSPLTSLLLAMNMGCTLFYMTPEEVLAGATVHAAQALG
LAHKGRIEVGCDADLALWDITRPADLAYQMGLNPIEGIMIKGAWR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=389, Percent_Identity=36.5038560411311, Blast_Score=199, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17555004, Length=385, Percent_Identity=29.3506493506493, Blast_Score=168, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 48720; Mature: 48720

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSSEQILDDSINTTDAMDALTTFDHIIINANLATFSAQYGFDTYADNKDSISAAAKST
CCCCHHHHHCCCCCCHHHHHHHHHHCEEEEECCHHEEEECCCCCCCCCCCHHHHHHHCCC
PYGQLENAAIGIKDSKIAWIGAHTQITPYLTHYQSQQITDADGHWITPGLIDCHTHIVYG
CCCCCCCCEEECCCCEEEEEECCCEECHHHHHHCCCCCCCCCCCEECCCEEECEEEEEEC
GNRSNEFEARLHGANYQDIAAQGGGIVSTVRSTREANIEELFAQSEKRLLALVKEGVTSI
CCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEE
EIKSGYGLDLKTERKMLKVARALGDKHNIHVSTTYLAAHALPPEYKDRVDDYIEQVCQWL
EECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHEEEECCCCCHHHHHHHHHHHHHHHHH
PILHSEGLVDAVDGFCENIAFTTEQIKRVFEVARSLNLPVKLHSEQLSNIGASALVAEYQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCHHHHHHHHC
GLSSDHLEHLVEDDIKKMATSNTVAVLLPGAFYTLRDTKLPPIEELRKHQVPMAISTDCN
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEECCCC
PGTSPLTSLLLAMNMGCTLFYMTPEEVLAGATVHAAQALGLAHKGRIEVGCDADLALWDI
CCCHHHHHHHHHHCCCCEEEEECHHHHHCCCHHHHHHHHCCCCCCCEEECCCCCEEEEEC
TRPADLAYQMGLNPIEGIMIKGAWR
CCCHHHHHHHCCCCHHCEEEECCCC
>Mature Secondary Structure
MNNSSEQILDDSINTTDAMDALTTFDHIIINANLATFSAQYGFDTYADNKDSISAAAKST
CCCCHHHHHCCCCCCHHHHHHHHHHCEEEEECCHHEEEECCCCCCCCCCCHHHHHHHCCC
PYGQLENAAIGIKDSKIAWIGAHTQITPYLTHYQSQQITDADGHWITPGLIDCHTHIVYG
CCCCCCCCEEECCCCEEEEEECCCEECHHHHHHCCCCCCCCCCCEECCCEEECEEEEEEC
GNRSNEFEARLHGANYQDIAAQGGGIVSTVRSTREANIEELFAQSEKRLLALVKEGVTSI
CCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEE
EIKSGYGLDLKTERKMLKVARALGDKHNIHVSTTYLAAHALPPEYKDRVDDYIEQVCQWL
EECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEHEEEECCCCCHHHHHHHHHHHHHHHHH
PILHSEGLVDAVDGFCENIAFTTEQIKRVFEVARSLNLPVKLHSEQLSNIGASALVAEYQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCHHHHHHHHC
GLSSDHLEHLVEDDIKKMATSNTVAVLLPGAFYTLRDTKLPPIEELRKHQVPMAISTDCN
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCHHHHHHCCCCEEEECCCC
PGTSPLTSLLLAMNMGCTLFYMTPEEVLAGATVHAAQALGLAHKGRIEVGCDADLALWDI
CCCHHHHHHHHHHCCCCEEEEECHHHHHCCCHHHHHHHHCCCCCCCEEECCCCCEEEEEC
TRPADLAYQMGLNPIEGIMIKGAWR
CCCHHHHHHHCCCCHHCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA