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The map label for this gene is 93006079

Identifier: 93006079

GI number: 93006079

Start: 1521948

End: 1522388

Strand: Reverse

Name: 93006079

Synonym: Pcryo_1251

Alternate gene names: NA

Gene position: 1522388-1521948 (Counterclockwise)

Preceding gene: 93006080

Following gene: 93006078

Centisome position: 49.75

GC content: 46.26

Gene sequence:

>441_bases
ATGACTTCAACCGCAGTAGAAATTACGGTAAAAAACGCTGCCGATATCGCTATTATCGGCGGTAGCGGTCTGTATCAAAT
GCAAGCTTTGACCAATAAGCGCAGCGTTAAAATTGAGACACCCTATGGTGAGCCATCTGATGACATCGTGCTCGGTGAAC
TTAATGGCGTCACAGTTGCATTCTTAACGCGGCATGGTCAAGGACACAGGTTAACCCCCTCTGAGGTGCCTTATCGTGCC
AACATCTATGCCTTAAAGACTTTAGGTGTACGCTATATCGTCTCAGTATCAGCGGTTGGCTCATTGCAAGAGAAGCTGAG
ACCATTAGATATGGTCATTCCCGATCAAATGATTGATATGACCAAGCAGAGAGTAAGCACGTTCTTTGGAGATGGTGCGG
TCGCCCATGTGTCAATGGCTGACCCTTTATCGAATCTTTAA

Upstream 100 bases:

>100_bases
TCTTGAAGGCGCTTGCTCAAGGTATGTATAAGAAGAGAGTCAGTAAACGCTAGTAGTATTAACTTTGATAGACTCTACCA
ATGATCATTTGGAACCCAAT

Downstream 100 bases:

>100_bases
TTGCTCTGTCCATCGCATTCGCTGCGTTAAACAATCTGGTACCAATGTTACGAGTGCGAGCCGTCTATCTAGCCTTTGTT
TTTGGTCTGATTCACGGGTT

Product: purine phosphorylase family 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MTSTAVEITVKNAADIAIIGGSGLYQMQALTNKRSVKIETPYGEPSDDIVLGELNGVTVAFLTRHGQGHRLTPSEVPYRA
NIYALKTLGVRYIVSVSAVGSLQEKLRPLDMVIPDQMIDMTKQRVSTFFGDGAVAHVSMADPLSNL

Sequences:

>Translated_146_residues
MTSTAVEITVKNAADIAIIGGSGLYQMQALTNKRSVKIETPYGEPSDDIVLGELNGVTVAFLTRHGQGHRLTPSEVPYRA
NIYALKTLGVRYIVSVSAVGSLQEKLRPLDMVIPDQMIDMTKQRVSTFFGDGAVAHVSMADPLSNL
>Mature_145_residues
TSTAVEITVKNAADIAIIGGSGLYQMQALTNKRSVKIETPYGEPSDDIVLGELNGVTVAFLTRHGQGHRLTPSEVPYRAN
IYALKTLGVRYIVSVSAVGSLQEKLRPLDMVIPDQMIDMTKQRVSTFFGDGAVAHVSMADPLSNL

Specific function: Unknown

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=142, Percent_Identity=40.8450704225352, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71980569, Length=136, Percent_Identity=44.1176470588235, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6323045, Length=151, Percent_Identity=39.7350993377483, Blast_Score=109, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20130079, Length=129, Percent_Identity=44.1860465116279, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221459247, Length=130, Percent_Identity=36.9230769230769, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: NA

Molecular weight: Translated: 15748; Mature: 15617

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTAVEITVKNAADIAIIGGSGLYQMQALTNKRSVKIETPYGEPSDDIVLGELNGVTVA
CCCCEEEEEEECCCCEEEECCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCEEEE
FLTRHGQGHRLTPSEVPYRANIYALKTLGVRYIVSVSAVGSLQEKLRPLDMVIPDQMIDM
EEEECCCCCCCCCCCCCEECEEEEEEECCEEEEEEHHHHHHHHHHCCCCCEECCHHHHHH
TKQRVSTFFGDGAVAHVSMADPLSNL
HHHHHHHHCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TSTAVEITVKNAADIAIIGGSGLYQMQALTNKRSVKIETPYGEPSDDIVLGELNGVTVA
CCCEEEEEEECCCCEEEECCCCCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCEEEE
FLTRHGQGHRLTPSEVPYRANIYALKTLGVRYIVSVSAVGSLQEKLRPLDMVIPDQMIDM
EEEECCCCCCCCCCCCCEECEEEEEEECCEEEEEEHHHHHHHHHHCCCCCEECCHHHHHH
TKQRVSTFFGDGAVAHVSMADPLSNL
HHHHHHHHCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]