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The map label for this gene is lolC [H]

Identifier: 93005617

GI number: 93005617

Start: 926645

End: 927880

Strand: Direct

Name: lolC [H]

Synonym: Pcryo_0787

Alternate gene names: 93005617

Gene position: 926645-927880 (Clockwise)

Preceding gene: 93005615

Following gene: 93005618

Centisome position: 30.28

GC content: 44.34

Gene sequence:

>1236_bases
ATGTTTCGTCCTTTAGCGTTATTTATCGGCTTACGGTACACCCGAGCAGAACGTAGTAATGGTTTTATCTCTTTTATATC
GCTGATCTCAATGATTGGTCTGACGCTTGGCGTGGCGGTATTGATTACCGTACTGTCGGTCATGAATGGCTTCGATCGTG
AGCTAAAAACGCGTATTTTGGGTATGGTACCGCAAGCGACTGTCACATCAACTGAGATTATCGGTGATTGGAAACAAGTC
GCGGACAAGATTAAAGAAGATCCAGAAGTGGTTGCAGTTGCGCCTTTTATCCAGTTGCAAGGTATGTTGACCTCGAATGG
TCAGGTAGCTGGCATCATGGTGACAGGTGTTGATCCTGAGTATGAGAAAAACGTTTCTATCATCAATGAGCATATGGTGG
AAGGCAATATTGATACGCTAAAGAATGGCGAGTTCGGTATTGTGCTTGGTGAAGGTATGGTGCAATCACTAGGACTGCAA
TTGGGTGACAAAGTCACTCTCGTGCTGCCAGAAGCATCGCCATCACCTGCTGGCGTGATACCACGCTTTAAACGCTTTAC
CTTGACCGGTATATTTTCTATCAGTCCAGAAGTAGACAGTCTCATGGCATTCATTCCAATGGGCGATGCGGCAAAATTAC
TGCGTTTACCAGAGGGCGCCCAAGGTATCCGTATGAAGCTTCATGATATCTTTACAGCGCCAATGGCAGCACAAAAAGCG
GCTGCGATTGCGCCAGAGCAATTATATCCTAGTGATTGGACCCAGACGCATGGCAATCTATTTGGTGCTATCCAAATGGA
AAAAGCCATGGTTGGCTTGCTACTGTTCTTAATCATCCTCGTGGCAGCTTTTAATATTGTTTCAAGTTTAGTGATGCTAG
TCACAGATAAAAAGGCTGACATTGCTATCTTAAAAACTTTTGGCGCCTCACCGCGTCTGATTACCCAAGTCTTTATGGTA
CAAGGTGTGGTGATTGGTTTTATTGGTACCATTGCAGGTACGATATTGGGCGTGATATTTGCATTAACGGTCAGTGATAT
TTTGGGCTTTATTAATAATAGCTTTGGTCTAAATTTATTTGATGCCTATTTTGTGAACTATCTACCATCGCAGCTGCGTT
TGGCGGATGTGGTATTGATTACCAGTGCGTCATTTATATTGAGCTTTTTGGCGACCATTTATCCAGCACGCCGAGCGGCT
AAAATTCAGCCTGCACAAACGCTGCGTTACGAGTAA

Upstream 100 bases:

>100_bases
TGATATGTTTTTGTGGCAGCTGCAAAAGTATGATGCAATTGCCGCTATTTGTTTTGTAACCTACATAAAGTCGCACGTAG
ATAAGATAAAGAGTTTGAAT

Downstream 100 bases:

>100_bases
TTTATAGGCGTTAATGCCGTTATAAATAAAATAAAGGAAGCATTATGTCTGCTATCTTAAAAGCGACCAATATTAATAAG
ATATACGATGAAGGTGCCGT

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MFRPLALFIGLRYTRAERSNGFISFISLISMIGLTLGVAVLITVLSVMNGFDRELKTRILGMVPQATVTSTEIIGDWKQV
ADKIKEDPEVVAVAPFIQLQGMLTSNGQVAGIMVTGVDPEYEKNVSIINEHMVEGNIDTLKNGEFGIVLGEGMVQSLGLQ
LGDKVTLVLPEASPSPAGVIPRFKRFTLTGIFSISPEVDSLMAFIPMGDAAKLLRLPEGAQGIRMKLHDIFTAPMAAQKA
AAIAPEQLYPSDWTQTHGNLFGAIQMEKAMVGLLLFLIILVAAFNIVSSLVMLVTDKKADIAILKTFGASPRLITQVFMV
QGVVIGFIGTIAGTILGVIFALTVSDILGFINNSFGLNLFDAYFVNYLPSQLRLADVVLITSASFILSFLATIYPARRAA
KIQPAQTLRYE

Sequences:

>Translated_411_residues
MFRPLALFIGLRYTRAERSNGFISFISLISMIGLTLGVAVLITVLSVMNGFDRELKTRILGMVPQATVTSTEIIGDWKQV
ADKIKEDPEVVAVAPFIQLQGMLTSNGQVAGIMVTGVDPEYEKNVSIINEHMVEGNIDTLKNGEFGIVLGEGMVQSLGLQ
LGDKVTLVLPEASPSPAGVIPRFKRFTLTGIFSISPEVDSLMAFIPMGDAAKLLRLPEGAQGIRMKLHDIFTAPMAAQKA
AAIAPEQLYPSDWTQTHGNLFGAIQMEKAMVGLLLFLIILVAAFNIVSSLVMLVTDKKADIAILKTFGASPRLITQVFMV
QGVVIGFIGTIAGTILGVIFALTVSDILGFINNSFGLNLFDAYFVNYLPSQLRLADVVLITSASFILSFLATIYPARRAA
KIQPAQTLRYE
>Mature_411_residues
MFRPLALFIGLRYTRAERSNGFISFISLISMIGLTLGVAVLITVLSVMNGFDRELKTRILGMVPQATVTSTEIIGDWKQV
ADKIKEDPEVVAVAPFIQLQGMLTSNGQVAGIMVTGVDPEYEKNVSIINEHMVEGNIDTLKNGEFGIVLGEGMVQSLGLQ
LGDKVTLVLPEASPSPAGVIPRFKRFTLTGIFSISPEVDSLMAFIPMGDAAKLLRLPEGAQGIRMKLHDIFTAPMAAQKA
AAIAPEQLYPSDWTQTHGNLFGAIQMEKAMVGLLLFLIILVAAFNIVSSLVMLVTDKKADIAILKTFGASPRLITQVFMV
QGVVIGFIGTIAGTILGVIFALTVSDILGFINNSFGLNLFDAYFVNYLPSQLRLADVVLITSASFILSFLATIYPARRAA
KIQPAQTLRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=411, Percent_Identity=37.4695863746959, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI1787360, Length=413, Percent_Identity=38.2566585956416, Blast_Score=237, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44459; Mature: 44459

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRPLALFIGLRYTRAERSNGFISFISLISMIGLTLGVAVLITVLSVMNGFDRELKTRIL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GMVPQATVTSTEIIGDWKQVADKIKEDPEVVAVAPFIQLQGMLTSNGQVAGIMVTGVDPE
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCEEECCCEEEEEEEECCCCC
YEKNVSIINEHMVEGNIDTLKNGEFGIVLGEGMVQSLGLQLGDKVTLVLPEASPSPAGVI
CCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCEEEEEEECCCCCCCCCC
PRFKRFTLTGIFSISPEVDSLMAFIPMGDAAKLLRLPEGAQGIRMKLHDIFTAPMAAQKA
CCHHHEEEEEEEECCCCHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHH
AAIAPEQLYPSDWTQTHGNLFGAIQMEKAMVGLLLFLIILVAAFNIVSSLVMLVTDKKAD
HHCCCHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IAILKTFGASPRLITQVFMVQGVVIGFIGTIAGTILGVIFALTVSDILGFINNSFGLNLF
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
DAYFVNYLPSQLRLADVVLITSASFILSFLATIYPARRAAKIQPAQTLRYE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
>Mature Secondary Structure
MFRPLALFIGLRYTRAERSNGFISFISLISMIGLTLGVAVLITVLSVMNGFDRELKTRIL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GMVPQATVTSTEIIGDWKQVADKIKEDPEVVAVAPFIQLQGMLTSNGQVAGIMVTGVDPE
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCEEECCCEEEEEEEECCCCC
YEKNVSIINEHMVEGNIDTLKNGEFGIVLGEGMVQSLGLQLGDKVTLVLPEASPSPAGVI
CCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCCCCCEEEEEEECCCCCCCCCC
PRFKRFTLTGIFSISPEVDSLMAFIPMGDAAKLLRLPEGAQGIRMKLHDIFTAPMAAQKA
CCHHHEEEEEEEECCCCHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHH
AAIAPEQLYPSDWTQTHGNLFGAIQMEKAMVGLLLFLIILVAAFNIVSSLVMLVTDKKAD
HHCCCHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IAILKTFGASPRLITQVFMVQGVVIGFIGTIAGTILGVIFALTVSDILGFINNSFGLNLF
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
DAYFVNYLPSQLRLADVVLITSASFILSFLATIYPARRAAKIQPAQTLRYE
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]