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The map label for this gene is hisZ [H]

Identifier: 93005474

GI number: 93005474

Start: 761974

End: 763137

Strand: Direct

Name: hisZ [H]

Synonym: Pcryo_0644

Alternate gene names: 93005474

Gene position: 761974-763137 (Clockwise)

Preceding gene: 93005471

Following gene: 93005475

Centisome position: 24.9

GC content: 46.05

Gene sequence:

>1164_bases
TTGCTGCCTGATGGGGTGGTTGATGTGTTGTTTGAAGACGCCCATAAACAAGAAGTGCTTAGACATCAATTGATCCAGCA
ACTTATCAGCCATGGCTATCAGTTGGTCAATCCGCCAATGATTGAGTTTACCGAATCACTACTGAGCGGTGCCTCAGAAG
ATCTAAAGCGTCAAACCTTTAAGATTATCGATCAGCTAACTGGTCGCTTAATGGGTATACGCGCGGATATCACGCCGCAG
ATTCTACGTATTGATGCACATCATGGCGGTGATGGAATCGCGCGTTATTGCTATGCAGGCGATGTCATTCATACCTTGCC
ATCGGGGCTTTTTGGTTCACGTACACCGTTGCAATTAGGCGCTGAGATATTTGGTTGTGAGTACATTGCAGCAGATATTG
AGCTGATTGATGTCTTATTTAGCATGCTCAATAGCCTAGAGATGAGCGCAGCATTACACGTTGATTTGGGTCATGTAGCG
ATATTTAAGCGCTTGGCAGAATTGGCAGTATTATCAGAAAGTGATACTGAGCAATTGATGCAGCTTTATGCCAATAAGAA
CTTGCCAGAGCTTAAGCAGGTTTGCCAAGCGCTACCGCTGGGTAGCGATTTTTATACCTTGGCGCGCTTTGGTCATGACA
TTGCAAATCTGCTTGGAAGATTGTCAGAGAATGCGCAACAAGACGCTCAAATTGTCACAGCTATTGATGAGCTGCAACGT
CTAAAAGCGCACTTGCAAGTACAGTGGCAGTGTGCGGTCAGTATCGATGTGACCGAGCTATCAGGCTATCATTATCATAC
GGGCATTGTGTTCAATGGTTATATCAATAGTGAAACTCAGCCACTGGTACGTGGCGGGCGCTTTGATGGTATGAAAAGTA
ATCAATTAGCCACGAATCAGCCACGTCAAGCGACCGGCTTTAGTATGGATGTCAGCCGTTTGCTCGCGCATACTCAGCTT
GATGCACCTGTTATTGTGCTGGTCGATTATGACGCTTTCAAGGATTTGGGTAGTGAGCAGCTGCAGCTATTATTACAGCA
AGTGGCAAGCTTACGTCAGCAGGGCTATCGCGTGACCATGCCATTAACGGCAAAAGATATTCCAGTGGGTATGACTCATC
GTTTAAGCCTTGTCGATAACCAATGGCAGCTACACGCAGTTTAA

Upstream 100 bases:

>100_bases
TACCCTCAAGCAAGCGGCTACTCAGCCCGCTGATAATACTGCCGCACCCAACCGTTTACCTTATTTAAGCAATCTTGCCA
GCGATGTTGCTAATAGCTGG

Downstream 100 bases:

>100_bases
CTTTGAAAATATTTAACATTTATAAATGCTATAAAAAAAGCGTTTGCTATAAAAAGATATTTAGTGATTAAGTCGTTAAA
AACATACTTTGTTTAAAGTA

Product: ATP phosphoribosyltransferase regulatory subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLPDGVVDVLFEDAHKQEVLRHQLIQQLISHGYQLVNPPMIEFTESLLSGASEDLKRQTFKIIDQLTGRLMGIRADITPQ
ILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGSRTPLQLGAEIFGCEYIAADIELIDVLFSMLNSLEMSAALHVDLGHVA
IFKRLAELAVLSESDTEQLMQLYANKNLPELKQVCQALPLGSDFYTLARFGHDIANLLGRLSENAQQDAQIVTAIDELQR
LKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYINSETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLAHTQL
DAPVIVLVDYDAFKDLGSEQLQLLLQQVASLRQQGYRVTMPLTAKDIPVGMTHRLSLVDNQWQLHAV

Sequences:

>Translated_387_residues
MLPDGVVDVLFEDAHKQEVLRHQLIQQLISHGYQLVNPPMIEFTESLLSGASEDLKRQTFKIIDQLTGRLMGIRADITPQ
ILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGSRTPLQLGAEIFGCEYIAADIELIDVLFSMLNSLEMSAALHVDLGHVA
IFKRLAELAVLSESDTEQLMQLYANKNLPELKQVCQALPLGSDFYTLARFGHDIANLLGRLSENAQQDAQIVTAIDELQR
LKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYINSETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLAHTQL
DAPVIVLVDYDAFKDLGSEQLQLLLQQVASLRQQGYRVTMPLTAKDIPVGMTHRLSLVDNQWQLHAV
>Mature_387_residues
MLPDGVVDVLFEDAHKQEVLRHQLIQQLISHGYQLVNPPMIEFTESLLSGASEDLKRQTFKIIDQLTGRLMGIRADITPQ
ILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGSRTPLQLGAEIFGCEYIAADIELIDVLFSMLNSLEMSAALHVDLGHVA
IFKRLAELAVLSESDTEQLMQLYANKNLPELKQVCQALPLGSDFYTLARFGHDIANLLGRLSENAQQDAQIVTAIDELQR
LKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYINSETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLAHTQL
DAPVIVLVDYDAFKDLGSEQLQLLLQQVASLRQQGYRVTMPLTAKDIPVGMTHRLSLVDNQWQLHAV

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43033; Mature: 43033

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDGVVDVLFEDAHKQEVLRHQLIQQLISHGYQLVNPPMIEFTESLLSGASEDLKRQTF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCHHHHHHHHH
KIIDQLTGRLMGIRADITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGSRTPLQLG
HHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHCHHHHHCCCCCCCCCCHHHHC
AEIFGCEYIAADIELIDVLFSMLNSLEMSAALHVDLGHVAIFKRLAELAVLSESDTEQLM
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCHHHHH
QLYANKNLPELKQVCQALPLGSDFYTLARFGHDIANLLGRLSENAQQDAQIVTAIDELQR
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYINSETQPLVRGGRFDGMKSNQLATNQ
HHHHHEEEEEEEEEEEEECCCCEEEEECEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCC
PRQATGFSMDVSRLLAHTQLDAPVIVLVDYDAFKDLGSEQLQLLLQQVASLRQQGYRVTM
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHCCCEEEE
PLTAKDIPVGMTHRLSLVDNQWQLHAV
CCCCCCCCCCCHHEEEEECCCEEEECC
>Mature Secondary Structure
MLPDGVVDVLFEDAHKQEVLRHQLIQQLISHGYQLVNPPMIEFTESLLSGASEDLKRQTF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHCCCHHHHHHHHH
KIIDQLTGRLMGIRADITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGSRTPLQLG
HHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHHHHHHHCHHHHHCCCCCCCCCCHHHHC
AEIFGCEYIAADIELIDVLFSMLNSLEMSAALHVDLGHVAIFKRLAELAVLSESDTEQLM
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCHHHHH
QLYANKNLPELKQVCQALPLGSDFYTLARFGHDIANLLGRLSENAQQDAQIVTAIDELQR
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYINSETQPLVRGGRFDGMKSNQLATNQ
HHHHHEEEEEEEEEEEEECCCCEEEEECEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCC
PRQATGFSMDVSRLLAHTQLDAPVIVLVDYDAFKDLGSEQLQLLLQQVASLRQQGYRVTM
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHCCCEEEE
PLTAKDIPVGMTHRLSLVDNQWQLHAV
CCCCCCCCCCCHHEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA