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The map label for this gene is ptp [H]

Identifier: 93005440

GI number: 93005440

Start: 725580

End: 726011

Strand: Direct

Name: ptp [H]

Synonym: Pcryo_0610

Alternate gene names: 93005440

Gene position: 725580-726011 (Clockwise)

Preceding gene: 93005439

Following gene: 93005441

Centisome position: 23.71

GC content: 40.05

Gene sequence:

>432_bases
ATGGCATTTGATCATATTCTAGTTGTGTGTGTTGGTAACATTTGTCGTAGTCCAATGGCGGAAGCACTCTTGAAACAGCG
TTTTCCTAATAAAATTATTGACTCTGCAGGTGTGGGTGCTTTGGTTGGTCATCCTGCTGATCCTGCTGCCCTAGAGATTA
TGTCAAAACAGCAGATTGATATTACCAGTCATATTGCTAAGCAAATTGATGAGCAGTTAGCAAAAAAAGTGGATCTTATT
TTCACTATGTCAGACGGTCAAACTAAGTGGATTGAAGAACGCTGGCCTTTTTGCCGTGGTAAAACCTTTAAACTAGGTCA
TTGGATGAATAAAGACATTGCTGATCCTTACAAGCATGAGATAAGTGCATTCGAGACTGCCCATCAAGACATTGTTGAAG
GTATAAAGCAATGGGCCGATAAAGTTAGCTAA

Upstream 100 bases:

>100_bases
ACTGGTTTGACGCGTTGGAACCGTGTCCTCAGTGCGTTATTACCATCAACTTCTGCAGTTACTGTTCTTTCTGGCTTATA
AATAATAGGTAATAACTATC

Downstream 100 bases:

>100_bases
GTGACTGTTGTGAATAAATAATTATTATAAAAGATTAATACTAAACGATTACCTCAAGTGATGAACCTACCGTTATGAAT
ACAGATTCGAAGAATGTATC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MAFDHILVVCVGNICRSPMAEALLKQRFPNKIIDSAGVGALVGHPADPAALEIMSKQQIDITSHIAKQIDEQLAKKVDLI
FTMSDGQTKWIEERWPFCRGKTFKLGHWMNKDIADPYKHEISAFETAHQDIVEGIKQWADKVS

Sequences:

>Translated_143_residues
MAFDHILVVCVGNICRSPMAEALLKQRFPNKIIDSAGVGALVGHPADPAALEIMSKQQIDITSHIAKQIDEQLAKKVDLI
FTMSDGQTKWIEERWPFCRGKTFKLGHWMNKDIADPYKHEISAFETAHQDIVEGIKQWADKVS
>Mature_142_residues
AFDHILVVCVGNICRSPMAEALLKQRFPNKIIDSAGVGALVGHPADPAALEIMSKQQIDITSHIAKQIDEQLAKKVDLIF
TMSDGQTKWIEERWPFCRGKTFKLGHWMNKDIADPYKHEISAFETAHQDIVEGIKQWADKVS

Specific function: Dephosphorylates ptk. May be involved in the production and the transport of exopolysaccharides [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=142, Percent_Identity=41.5492957746479, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87081812, Length=144, Percent_Identity=36.8055555555556, Blast_Score=105, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78706766, Length=139, Percent_Identity=33.8129496402878, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI78706768, Length=139, Percent_Identity=33.8129496402878, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16100; Mature: 15969

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDHILVVCVGNICRSPMAEALLKQRFPNKIIDSAGVGALVGHPADPAALEIMSKQQID
CCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCHHCCCCCCHHHHHHHHHHCHH
ITSHIAKQIDEQLAKKVDLIFTMSDGQTKWIEERWPFCRGKTFKLGHWMNKDIADPYKHE
HHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHH
ISAFETAHQDIVEGIKQWADKVS
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFDHILVVCVGNICRSPMAEALLKQRFPNKIIDSAGVGALVGHPADPAALEIMSKQQID
CCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCHHCCCCCCHHHHHHHHHHCHH
ITSHIAKQIDEQLAKKVDLIFTMSDGQTKWIEERWPFCRGKTFKLGHWMNKDIADPYKHE
HHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHH
ISAFETAHQDIVEGIKQWADKVS
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9434192; 9571056 [H]