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The map label for this gene is nuoH [H]

Identifier: 93005409

GI number: 93005409

Start: 692289

End: 693332

Strand: Direct

Name: nuoH [H]

Synonym: Pcryo_0579

Alternate gene names: 93005409

Gene position: 692289-693332 (Clockwise)

Preceding gene: 93005408

Following gene: 93005410

Centisome position: 22.62

GC content: 42.91

Gene sequence:

>1044_bases
ATGCAAGTAACTCGTATTATCCCTGATGTGCCAAGTTTTTTGGCAAGTATGATGACCTTTGATACTTGGTCCATACTTTT
TATGGTCGTACAATCGTTGGTTATCTTTTTAGTCGTTGTCATTGTCGCGGCAATGATGATTATCTATGAGCGCCGGATGC
TAGCACTCTGGCAAGACCGTTATGGTCCAAACCGTGTTGGACCGTTTGGTTCACTACAGCTAGTCGCCGATATGCTCAAA
ATCTTCTTTAAAGAAGATTGGACGCCAAATTTTACCGATAAGTTTATGTTTACTTTGGCGCCTGCGGTTGCCATGTTTAC
CGCTCTGGCTTCATTTGCCATTATTCCTATCTCACCAACCCTTGGCGTTGCTGATTGGGATATTGGTATTTTGTTCTTTT
TTGCCATGGCTGGTATTGCAGTCTATGCAGTACTGTTCGGTGGTTGGGCATCAGCCAATAAATTCTCATTACTTGGTGGC
TTACGTTCAGCCGCGCAAACCATCAGTTATGAAGTGTTCTTAGGCTTGTCGTTGATGGGTGTTGTTGCATTGACTGGCTC
ATTTAACTTACGTGCGATTGTTGAAGCACAAGCTGATGGTTGGTATATCATCCCGCAGTTCTTTGGCTTTTTAACCTTTG
TCGTTGCTGGTGTTGCGGTCACGCATAGACATCCATTTGACCAACCAGAAGCTGAGCAAGAGCTTGCTGAAGGGTATCAC
GTTGAATATTCCGGCATGAAGTTCGGTATGTTCTTTATTGGCGAATACGTCAATGTTGTATTAATTTCTGCTTTGATGAC
TTGTTTGTTCTTTGGTGGTTGGCTTGCACCTTTTAATTTAGATATTCCATTTATTCCACCAGCTTTTTGGTTCATGATTA
AGACGCTGTTCTTTATGACTATGTTTGTTTTGGCTCGAGGCTCACTCATGCGTCCGCGCTATGATCAGGTGATGAACTTT
GGCTGGAAAGTCTGCCTGCCCGTAACCTTGATTAATCTATTGGTTACTGCTGCAGTCATTTTGATTTTTTCCCCAACGTT
GTAA

Upstream 100 bases:

>100_bases
GGCAATTCTGAAAATGGCAGTGCTTTAAACAGCTTTGAAGATAACAATAACCGCGCCGTAACAATAAGCACAGCGCCGAC
CACCACACAGGAGGTGTAAT

Downstream 100 bases:

>100_bases
TCATCACTAGCCATCACTGATGAACTAGGGTAAAGCTGAGAAGGATAATAATCCCATGTTTACTACGATAAAAAAGACCG
TCATTGGACTATTTACCATT

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQVTRIIPDVPSFLASMMTFDTWSILFMVVQSLVIFLVVVIVAAMMIIYERRMLALWQDRYGPNRVGPFGSLQLVADMLK
IFFKEDWTPNFTDKFMFTLAPAVAMFTALASFAIIPISPTLGVADWDIGILFFFAMAGIAVYAVLFGGWASANKFSLLGG
LRSAAQTISYEVFLGLSLMGVVALTGSFNLRAIVEAQADGWYIIPQFFGFLTFVVAGVAVTHRHPFDQPEAEQELAEGYH
VEYSGMKFGMFFIGEYVNVVLISALMTCLFFGGWLAPFNLDIPFIPPAFWFMIKTLFFMTMFVLARGSLMRPRYDQVMNF
GWKVCLPVTLINLLVTAAVILIFSPTL

Sequences:

>Translated_347_residues
MQVTRIIPDVPSFLASMMTFDTWSILFMVVQSLVIFLVVVIVAAMMIIYERRMLALWQDRYGPNRVGPFGSLQLVADMLK
IFFKEDWTPNFTDKFMFTLAPAVAMFTALASFAIIPISPTLGVADWDIGILFFFAMAGIAVYAVLFGGWASANKFSLLGG
LRSAAQTISYEVFLGLSLMGVVALTGSFNLRAIVEAQADGWYIIPQFFGFLTFVVAGVAVTHRHPFDQPEAEQELAEGYH
VEYSGMKFGMFFIGEYVNVVLISALMTCLFFGGWLAPFNLDIPFIPPAFWFMIKTLFFMTMFVLARGSLMRPRYDQVMNF
GWKVCLPVTLINLLVTAAVILIFSPTL
>Mature_347_residues
MQVTRIIPDVPSFLASMMTFDTWSILFMVVQSLVIFLVVVIVAAMMIIYERRMLALWQDRYGPNRVGPFGSLQLVADMLK
IFFKEDWTPNFTDKFMFTLAPAVAMFTALASFAIIPISPTLGVADWDIGILFFFAMAGIAVYAVLFGGWASANKFSLLGG
LRSAAQTISYEVFLGLSLMGVVALTGSFNLRAIVEAQADGWYIIPQFFGFLTFVVAGVAVTHRHPFDQPEAEQELAEGYH
VEYSGMKFGMFFIGEYVNVVLISALMTCLFFGGWLAPFNLDIPFIPPAFWFMIKTLFFMTMFVLARGSLMRPRYDQVMNF
GWKVCLPVTLINLLVTAAVILIFSPTL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=287, Percent_Identity=36.2369337979094, Blast_Score=188, Evalue=8e-48,
Organism=Escherichia coli, GI1788618, Length=318, Percent_Identity=66.9811320754717, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1789077, Length=234, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38827; Mature: 38827

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTRIIPDVPSFLASMMTFDTWSILFMVVQSLVIFLVVVIVAAMMIIYERRMLALWQDR
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YGPNRVGPFGSLQLVADMLKIFFKEDWTPNFTDKFMFTLAPAVAMFTALASFAIIPISPT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
LGVADWDIGILFFFAMAGIAVYAVLFGGWASANKFSLLGGLRSAAQTISYEVFLGLSLMG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVALTGSFNLRAIVEAQADGWYIIPQFFGFLTFVVAGVAVTHRHPFDQPEAEQELAEGYH
HHHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCE
VEYSGMKFGMFFIGEYVNVVLISALMTCLFFGGWLAPFNLDIPFIPPAFWFMIKTLFFMT
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MFVLARGSLMRPRYDQVMNFGWKVCLPVTLINLLVTAAVILIFSPTL
HHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVTRIIPDVPSFLASMMTFDTWSILFMVVQSLVIFLVVVIVAAMMIIYERRMLALWQDR
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YGPNRVGPFGSLQLVADMLKIFFKEDWTPNFTDKFMFTLAPAVAMFTALASFAIIPISPT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
LGVADWDIGILFFFAMAGIAVYAVLFGGWASANKFSLLGGLRSAAQTISYEVFLGLSLMG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVALTGSFNLRAIVEAQADGWYIIPQFFGFLTFVVAGVAVTHRHPFDQPEAEQELAEGYH
HHHHCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCE
VEYSGMKFGMFFIGEYVNVVLISALMTCLFFGGWLAPFNLDIPFIPPAFWFMIKTLFFMT
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MFVLARGSLMRPRYDQVMNFGWKVCLPVTLINLLVTAAVILIFSPTL
HHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA