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The map label for this gene is ilvC [H]

Identifier: 93005354

GI number: 93005354

Start: 620640

End: 621656

Strand: Direct

Name: ilvC [H]

Synonym: Pcryo_0524

Alternate gene names: 93005354

Gene position: 620640-621656 (Clockwise)

Preceding gene: 93005353

Following gene: 93005355

Centisome position: 20.28

GC content: 43.46

Gene sequence:

>1017_bases
ATGAACGTTTATTATGATAAAGATTGTGATCTATCAATCGTCCAAGGTAAAAAAGTCGCCATTATTGGTTATGGTTCACA
AGGTCATGCGCACGCGCTTAACCTACAAGATTCAAACGTCGATGTGACGGTTGGTCTACGTGCTAACTCTGGCTCATGGA
AGAAAGCAGAAAATGCTGGCTTAAAAGTTGCTGAAGTAGAAGAGGCGGTAAAAGCGGCTGACATCATCATGATTTTGACG
CCTGATGAGTTCCAAAAAGAGCTTTATAACGATGTGATTGAGCCAAACATCAAGCAGGGCGCAACACTAGCCTTTGCTCA
TGGTTTTGCGATTCATTATAACCAAGTTATACCACGTAGCGATCTTGACGTCATCATGGTGGCACCAAAAGCACCAGGTC
ATACCGTTCGTTCAGAGTTTGCTAAAGGCGGTGGTATCCCAGATCTTATCGCTATCTATCAAGATGCGTCAGGTCAAGCC
AAGCAATTAGCACTATCTTATGCTGCTGGTGTTGGTGGTGGACGTTCAGGTATTATCGAAACGACCTTTAAAGATGAAAC
TGAAACTGACCTATTTGGTGAGCAAGCGGTTCTTTGTGGTGGCGCAGTAGAGCTAGTAAAAATGGGTTTTGAGACCTTAA
CTGAAGCGGGCTATGCACCAGAAATGGCTTACTTTGAGTGCTTACATGAGCTAAAGCTTATTGTCGACTTGATGTATGAA
GGCGGTATCGCTGACATGAACTACTCAATCAGTAACAACGCTGAATATGGCGAATATGTGACTGGTCCTGAAGTGATCAA
TGAGCAATCACGTGAAGCCATGCGTAATGCGTTAAAACGCATTCAATCTGGCGAATACGCAAAAATGTTCATCAGTGAAG
GTGCGACCAATTATCCATCAATGACTGCTCGTCGTCGTAACAATGCAGAGCATCAAATCGAAATCACAGGCGCTAAGCTA
CGTGGTATGATGCCTTGGATCGGTGGCAATAAAATCATCGATAAAGACAAAAACTAA

Upstream 100 bases:

>100_bases
CAACATAGCGCTTATCTCACCAATCACTTCGATAAGGTGACTATAATTTAAGTGTTTATTTATCCATGGTACGCCATGAT
TTAGGAAAAGGACTCTGTTT

Downstream 100 bases:

>100_bases
TTTGCTATTGAGCATTAGTAAAAAAATTAGTCTAAAAAAGCCCATGTTATCAGTGATAGCATGGGCTTTTTATTTTTAGT
AGGCGATGTTTTATAAAGTA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNVYYDKDCDLSIVQGKKVAIIGYGSQGHAHALNLQDSNVDVTVGLRANSGSWKKAENAGLKVAEVEEAVKAADIIMILT
PDEFQKELYNDVIEPNIKQGATLAFAHGFAIHYNQVIPRSDLDVIMVAPKAPGHTVRSEFAKGGGIPDLIAIYQDASGQA
KQLALSYAAGVGGGRSGIIETTFKDETETDLFGEQAVLCGGAVELVKMGFETLTEAGYAPEMAYFECLHELKLIVDLMYE
GGIADMNYSISNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFISEGATNYPSMTARRRNNAEHQIEITGAKL
RGMMPWIGGNKIIDKDKN

Sequences:

>Translated_338_residues
MNVYYDKDCDLSIVQGKKVAIIGYGSQGHAHALNLQDSNVDVTVGLRANSGSWKKAENAGLKVAEVEEAVKAADIIMILT
PDEFQKELYNDVIEPNIKQGATLAFAHGFAIHYNQVIPRSDLDVIMVAPKAPGHTVRSEFAKGGGIPDLIAIYQDASGQA
KQLALSYAAGVGGGRSGIIETTFKDETETDLFGEQAVLCGGAVELVKMGFETLTEAGYAPEMAYFECLHELKLIVDLMYE
GGIADMNYSISNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFISEGATNYPSMTARRRNNAEHQIEITGAKL
RGMMPWIGGNKIIDKDKN
>Mature_338_residues
MNVYYDKDCDLSIVQGKKVAIIGYGSQGHAHALNLQDSNVDVTVGLRANSGSWKKAENAGLKVAEVEEAVKAADIIMILT
PDEFQKELYNDVIEPNIKQGATLAFAHGFAIHYNQVIPRSDLDVIMVAPKAPGHTVRSEFAKGGGIPDLIAIYQDASGQA
KQLALSYAAGVGGGRSGIIETTFKDETETDLFGEQAVLCGGAVELVKMGFETLTEAGYAPEMAYFECLHELKLIVDLMYE
GGIADMNYSISNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFISEGATNYPSMTARRRNNAEHQIEITGAKL
RGMMPWIGGNKIIDKDKN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=316, Percent_Identity=35.126582278481, Blast_Score=171, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6323387, Length=233, Percent_Identity=36.480686695279, Blast_Score=132, Evalue=9e-32,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 36799; Mature: 36799

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVYYDKDCDLSIVQGKKVAIIGYGSQGHAHALNLQDSNVDVTVGLRANSGSWKKAENAG
CCCEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEEEEECCCCCCCHHCCC
LKVAEVEEAVKAADIIMILTPDEFQKELYNDVIEPNIKQGATLAFAHGFAIHYNQVIPRS
CCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCCCCC
DLDVIMVAPKAPGHTVRSEFAKGGGIPDLIAIYQDASGQAKQLALSYAAGVGGGRSGIIE
CCCEEEECCCCCCHHHHHHHHCCCCCCHHHHEEECCCCHHHHHHHHHHHCCCCCCCCEEE
TTFKDETETDLFGEQAVLCGGAVELVKMGFETLTEAGYAPEMAYFECLHELKLIVDLMYE
ECCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GGIADMNYSISNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFISEGATNYPS
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCC
MTARRRNNAEHQIEITGAKLRGMMPWIGGNKIIDKDKN
HHHHHCCCCCEEEEEECHHHCCCCCCCCCCEECCCCCC
>Mature Secondary Structure
MNVYYDKDCDLSIVQGKKVAIIGYGSQGHAHALNLQDSNVDVTVGLRANSGSWKKAENAG
CCCEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEEEEECCCCCCCHHCCC
LKVAEVEEAVKAADIIMILTPDEFQKELYNDVIEPNIKQGATLAFAHGFAIHYNQVIPRS
CCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCCCCC
DLDVIMVAPKAPGHTVRSEFAKGGGIPDLIAIYQDASGQAKQLALSYAAGVGGGRSGIIE
CCCEEEECCCCCCHHHHHHHHCCCCCCHHHHEEECCCCHHHHHHHHHHHCCCCCCCCEEE
TTFKDETETDLFGEQAVLCGGAVELVKMGFETLTEAGYAPEMAYFECLHELKLIVDLMYE
ECCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GGIADMNYSISNNAEYGEYVTGPEVINEQSREAMRNALKRIQSGEYAKMFISEGATNYPS
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCC
MTARRRNNAEHQIEITGAKLRGMMPWIGGNKIIDKDKN
HHHHHCCCCCEEEEEECHHHCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA