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The map label for this gene is fabG3 [H]

Identifier: 93005247

GI number: 93005247

Start: 506802

End: 507590

Strand: Reverse

Name: fabG3 [H]

Synonym: Pcryo_0417

Alternate gene names: 93005247

Gene position: 507590-506802 (Counterclockwise)

Preceding gene: 93005248

Following gene: 93005246

Centisome position: 16.59

GC content: 43.85

Gene sequence:

>789_bases
ATGAATATATTCATTACGGGTGCATCACGCGGTATCGGTCTAGCGACAGCAAAACGATTGCTCGCAAAAGGTCATAGCGT
CGGTCTTTTTGATATTGACACGGTTGAGCTTGAGCGTGCGATTGATGATAAAACTTTTAAAAAAGCGCTAAAAGGCAATC
GTCTCGTCCATGGTCATCTAGATGTCATTGACCCTGAAGCATGGGATACGGCAATCGATCATATGCTGGAGAATTTTGGT
GGTATTGATGTCTTGATTAATAATGCTGGCGTATTGGTGAGTGGCGCGTTGCCCCATACTGACTTGGACAAGCAATTGTC
ATTGATTGATATCAATTGTAAAGGTGTGCTCATCGGCTGTCATAAGCTAGCGCCGCATTTAGCCGACAGCAAAAACGCCA
AAATCATCAATCTCTCATCTGCCTCAGCGATATATGGTCAATCTGAAGTGGCACCTTATTCTGCCAGTAAATTCTTTGTC
CGCGGTTTAACCGAAGGGCTAAACATTGAATATGTTGAGCTAGGCATCAAAGTGATTGATGTCATGCCATTGTGGGTAAA
ATCCGACATGACGAAAGACATCAAGGTCACCAGTATCGACCGTTTGGGCATCAATCTAACCGTTGACGATGTGGCTAAGA
CCTTGTGTAAATTAAGCGCTCAGCCGAATCGTAAACTGTCACGGACTCACTATCCTATTGGCTTTCCTGCGAAAATGCTG
CATACAGCCTCGCAAGTCGCACCTGACTCATTAATGCGCTTTATCAATAGTAAAATCGGTACTAAATAA

Upstream 100 bases:

>100_bases
GCATTTGTCTTAGCGCTAACTTTTAATAGAGAGTTTGCTATACTAAAAATTAGCGCATTTTTTTAGGCATCATTTATCAT
CAATCATTAAGCGAGTCATT

Downstream 100 bases:

>100_bases
ATTTAGACTATAAAAATTCAAAAGTAACATGACAATATTTAAACGGCTACCAAGATTTGGCAGCCGTTTTTTTACGGTTA
AATAAGCAACCTTCGTACAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNIFITGASRGIGLATAKRLLAKGHSVGLFDIDTVELERAIDDKTFKKALKGNRLVHGHLDVIDPEAWDTAIDHMLENFG
GIDVLINNAGVLVSGALPHTDLDKQLSLIDINCKGVLIGCHKLAPHLADSKNAKIINLSSASAIYGQSEVAPYSASKFFV
RGLTEGLNIEYVELGIKVIDVMPLWVKSDMTKDIKVTSIDRLGINLTVDDVAKTLCKLSAQPNRKLSRTHYPIGFPAKML
HTASQVAPDSLMRFINSKIGTK

Sequences:

>Translated_262_residues
MNIFITGASRGIGLATAKRLLAKGHSVGLFDIDTVELERAIDDKTFKKALKGNRLVHGHLDVIDPEAWDTAIDHMLENFG
GIDVLINNAGVLVSGALPHTDLDKQLSLIDINCKGVLIGCHKLAPHLADSKNAKIINLSSASAIYGQSEVAPYSASKFFV
RGLTEGLNIEYVELGIKVIDVMPLWVKSDMTKDIKVTSIDRLGINLTVDDVAKTLCKLSAQPNRKLSRTHYPIGFPAKML
HTASQVAPDSLMRFINSKIGTK
>Mature_262_residues
MNIFITGASRGIGLATAKRLLAKGHSVGLFDIDTVELERAIDDKTFKKALKGNRLVHGHLDVIDPEAWDTAIDHMLENFG
GIDVLINNAGVLVSGALPHTDLDKQLSLIDINCKGVLIGCHKLAPHLADSKNAKIINLSSASAIYGQSEVAPYSASKFFV
RGLTEGLNIEYVELGIKVIDVMPLWVKSDMTKDIKVTSIDRLGINLTVDDVAKTLCKLSAQPNRKLSRTHYPIGFPAKML
HTASQVAPDSLMRFINSKIGTK

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=31.4432989690722, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI20149619, Length=208, Percent_Identity=25.4807692307692, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790717, Length=193, Percent_Identity=31.6062176165803, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=33.8383838383838, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787335, Length=189, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787820, Length=230, Percent_Identity=24.3478260869565, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=25.9067357512953, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=196, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=198, Percent_Identity=30.8080808080808, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=234, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=192, Percent_Identity=31.7708333333333, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=251, Percent_Identity=27.0916334661355, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571387, Length=243, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281364892, Length=212, Percent_Identity=26.4150943396226, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356301, Length=183, Percent_Identity=25.6830601092896, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=233, Percent_Identity=29.1845493562232, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357673, Length=189, Percent_Identity=28.042328042328, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.53 [H]

Molecular weight: Translated: 28450; Mature: 28450

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFITGASRGIGLATAKRLLAKGHSVGLFDIDTVELERAIDDKTFKKALKGNRLVHGHL
CEEEEECCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHCHHHHHHHHCCCCEEEECC
DVIDPEAWDTAIDHMLENFGGIDVLINNAGVLVSGALPHTDLDKQLSLIDINCKGVLIGC
CEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCCCEEEEEECCCEEEEEH
HKLAPHLADSKNAKIINLSSASAIYGQSEVAPYSASKFFVRGLTEGLNIEYVELGIKVID
HHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECEEEEE
VMPLWVKSDMTKDIKVTSIDRLGINLTVDDVAKTLCKLSAQPNRKLSRTHYPIGFPAKML
EEEHHHHCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
HTASQVAPDSLMRFINSKIGTK
HHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIFITGASRGIGLATAKRLLAKGHSVGLFDIDTVELERAIDDKTFKKALKGNRLVHGHL
CEEEEECCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHHHHCHHHHHHHHCCCCEEEECC
DVIDPEAWDTAIDHMLENFGGIDVLINNAGVLVSGALPHTDLDKQLSLIDINCKGVLIGC
CEECCHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCCCCCEEEEEECCCEEEEEH
HKLAPHLADSKNAKIINLSSASAIYGQSEVAPYSASKFFVRGLTEGLNIEYVELGIKVID
HHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECEEEEE
VMPLWVKSDMTKDIKVTSIDRLGINLTVDDVAKTLCKLSAQPNRKLSRTHYPIGFPAKML
EEEHHHHCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
HTASQVAPDSLMRFINSKIGTK
HHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]