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The map label for this gene is era [H]

Identifier: 93005198

GI number: 93005198

Start: 446694

End: 447710

Strand: Direct

Name: era [H]

Synonym: Pcryo_0368

Alternate gene names: 93005198

Gene position: 446694-447710 (Clockwise)

Preceding gene: 93005197

Following gene: 93005199

Centisome position: 14.6

GC content: 41.89

Gene sequence:

>1017_bases
ATGAGTGAAGTAGAAATCAATGAAACAGAAAACAATGCAGTAGATAACGATTCAGCAATCGAAGATTTCTTTTCACCAAA
TAATGGCGCGCTTGCTGCTGAAGGTTTTAAAACTGGCTATGTCGCCATTGTTGGTCGTCCAAATGTCGGCAAATCAACGC
TGATGAACCATTTATTGGGTCAAAAGCTGTCCATCACCTCACGTAAACCACAAACGACGCGCCATCGTATCCATGGTATT
TTGTCTAATGATGAGATGCAGGCAGTATTTGTTGATACCCCCGGCATTCATCGCAACGAAGTACGTGCTATCAATGAACG
CATGAATAAAGCGGCCGTCTCTGCATTGGTAGATGTAGACTTGGTATTGTTTGTCGTTGATTCTGATCAATGGCGTGACG
ATGATTTACTGGTTCTACAAAAGCTTGGCGATACCAATTTAAATGTGGTTTTAGTGATTAATAAAGCGGATACCTTAAAA
GATAAAGGCAGCGTTTTACCGTTAATGGAAACCTTTAACGACAGTTTTGATTTTGCCGATATCGTCCCCGTTTCTGCATT
AAAGAATCAAAACTTAGATCGTCTGCAAGAAGTGATCGCATCACATTTACCAGTCGCTGCGCCAATTTATGATACGGAAC
AAATCACCGATCGCTCAGAGCGTTTCTTAGCCAGTGAAATCATTCGTGAAAAAATCATGCGTAGTGCTGGTGATGAAGTA
CCGTACGATTTAACGGTACAAATTGACGGCTTTAAAGATGAAGCGGCTCATACTGACCCAAAAACTGGTCGTCCACGTAA
AGCCTGTACCTTTATCGATGCCACTATTTATGTTGAACGTAGCGGGCAAAAAGCGATTGTGATTGGTGACAAAGGGCAAC
GTATCAAACAAGTCGGTATGGATGCTCGTAAAGATATGGAGCAGCTGTTTGATAAAAAAATCATGTTAACGCTGTGGGTA
AAAGTTAAGCGCGGTTGGTCGGATGATGAAAGAGCCTTGACCAGTTTAGGCTATTAA

Upstream 100 bases:

>100_bases
TATGAGCAATCATACTGACTTGCCATTAAACAATGAAGATAATGCCACAAATATGACCGAAAATACTGACCTAAATACAA
GTACAAATAATGCAGTAGAA

Downstream 100 bases:

>100_bases
AAATATTAATAGCGACTCTCTTTTATATTGAGTGAACTATAGCTGAGGTAATAATCATGCGTAACGAAGCGTTAATCGGT
TATTTATTACATCAGCGCCC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSEVEINETENNAVDNDSAIEDFFSPNNGALAAEGFKTGYVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHRIHGI
LSNDEMQAVFVDTPGIHRNEVRAINERMNKAAVSALVDVDLVLFVVDSDQWRDDDLLVLQKLGDTNLNVVLVINKADTLK
DKGSVLPLMETFNDSFDFADIVPVSALKNQNLDRLQEVIASHLPVAAPIYDTEQITDRSERFLASEIIREKIMRSAGDEV
PYDLTVQIDGFKDEAAHTDPKTGRPRKACTFIDATIYVERSGQKAIVIGDKGQRIKQVGMDARKDMEQLFDKKIMLTLWV
KVKRGWSDDERALTSLGY

Sequences:

>Translated_338_residues
MSEVEINETENNAVDNDSAIEDFFSPNNGALAAEGFKTGYVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHRIHGI
LSNDEMQAVFVDTPGIHRNEVRAINERMNKAAVSALVDVDLVLFVVDSDQWRDDDLLVLQKLGDTNLNVVLVINKADTLK
DKGSVLPLMETFNDSFDFADIVPVSALKNQNLDRLQEVIASHLPVAAPIYDTEQITDRSERFLASEIIREKIMRSAGDEV
PYDLTVQIDGFKDEAAHTDPKTGRPRKACTFIDATIYVERSGQKAIVIGDKGQRIKQVGMDARKDMEQLFDKKIMLTLWV
KVKRGWSDDERALTSLGY
>Mature_337_residues
SEVEINETENNAVDNDSAIEDFFSPNNGALAAEGFKTGYVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHRIHGIL
SNDEMQAVFVDTPGIHRNEVRAINERMNKAAVSALVDVDLVLFVVDSDQWRDDDLLVLQKLGDTNLNVVLVINKADTLKD
KGSVLPLMETFNDSFDFADIVPVSALKNQNLDRLQEVIASHLPVAAPIYDTEQITDRSERFLASEIIREKIMRSAGDEVP
YDLTVQIDGFKDEAAHTDPKTGRPRKACTFIDATIYVERSGQKAIVIGDKGQRIKQVGMDARKDMEQLFDKKIMLTLWVK
VKRGWSDDERALTSLGY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=335, Percent_Identity=24.7761194029851, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788919, Length=302, Percent_Identity=51.9867549668874, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24646434, Length=338, Percent_Identity=25.1479289940828, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37743; Mature: 37612

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVEINETENNAVDNDSAIEDFFSPNNGALAAEGFKTGYVAIVGRPNVGKSTLMNHLLG
CCCEECCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHC
QKLSITSRKPQTTRHRIHGILSNDEMQAVFVDTPGIHRNEVRAINERMNKAAVSALVDVD
CCEEECCCCCHHHHHHHHEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEE
LVLFVVDSDQWRDDDLLVLQKLGDTNLNVVLVINKADTLKDKGSVLPLMETFNDSFDFAD
EEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCEEHHHHHCCCCCCHHH
IVPVSALKNQNLDRLQEVIASHLPVAAPIYDTEQITDRSERFLASEIIREKIMRSAGDEV
HCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PYDLTVQIDGFKDEAAHTDPKTGRPRKACTFIDATIYVERSGQKAIVIGDKGQRIKQVGM
CEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCHHHHHHCC
DARKDMEQLFDKKIMLTLWVKVKRGWSDDERALTSLGY
HHHHHHHHHHCCCEEEEEEEEHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SEVEINETENNAVDNDSAIEDFFSPNNGALAAEGFKTGYVAIVGRPNVGKSTLMNHLLG
CCEECCCCCCCCCCCCHHHHHHCCCCCCCEEECCCCCCEEEEEECCCCCHHHHHHHHHC
QKLSITSRKPQTTRHRIHGILSNDEMQAVFVDTPGIHRNEVRAINERMNKAAVSALVDVD
CCEEECCCCCHHHHHHHHEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEE
LVLFVVDSDQWRDDDLLVLQKLGDTNLNVVLVINKADTLKDKGSVLPLMETFNDSFDFAD
EEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCEEHHHHHCCCCCCHHH
IVPVSALKNQNLDRLQEVIASHLPVAAPIYDTEQITDRSERFLASEIIREKIMRSAGDEV
HCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PYDLTVQIDGFKDEAAHTDPKTGRPRKACTFIDATIYVERSGQKAIVIGDKGQRIKQVGM
CEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCHHHHHHCC
DARKDMEQLFDKKIMLTLWVKVKRGWSDDERALTSLGY
HHHHHHHHHHCCCEEEEEEEEHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]