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The map label for this gene is pgsA [H]

Identifier: 93005037

GI number: 93005037

Start: 244112

End: 244792

Strand: Direct

Name: pgsA [H]

Synonym: Pcryo_0206

Alternate gene names: 93005037

Gene position: 244112-244792 (Clockwise)

Preceding gene: 93005036

Following gene: 93005039

Centisome position: 7.98

GC content: 44.79

Gene sequence:

>681_bases
ATGACTGAGAGCACGCATTTGCATCCGCAGGAGCCGTCAAGTACGCAGAATAACAAAAGTATTTTTAATTTGCCCAATAA
CCTGACGATTGCGCGTATCTTGATGATTCCGCTATTTGTTGCGATTGCCTATTGGCCACCTGCTATGGGGATCGGCATGC
CCGCAATCTCTGATAACGTGATTGCAAAGGTTGGTATGAGTGACTTTAGCGACAGTCTATTGCGTCACTTGTTATTAACA
GGCGTTTTTATCCTAGCAGCCATTACCGATTGGCTTGATGGCTATTTTGCCCGTAAGCTCAATGTGGTATCAGCCTTTGG
TCGATTTTTAGACCCAGTCGCTGATAAGCTGATGGTAGCAGCCGCGCTTATTATCTTAGTGCAATGGCATCCCAATATCA
TCATGGCGATAGCAGCAATTGTGATTATCTCGCGTGAAATCGCCGTATCGGCATTGCGTGAATGGATGGCAGAACTGGGT
AAAAGTACCAGTGTGGCGGTGTCTTATGTAGGTAAGCTCAAAACCACCTTTCAGATGATAGCGATTACGGTGCTTTTGTT
AAATTGGGAATCGCTTGAAACCATCGGCTATGTATTGATGGTAGCGGCAGTGATTTTGACCTTATGGTCGATGATGATTT
ATCTTAAAGCTGCGTGGCCGTATTTAAAACAAAGTGGGTAA

Upstream 100 bases:

>100_bases
ACGCTTGGCATAAACGATACCTACATAGAGGGCATGACGACTTGGCTGAAAAATGCTAAGCTATCCGTCATTATTAGGTC
AATATTAAACTGGGTTTGCC

Downstream 100 bases:

>100_bases
AAGGTAGCTAAGTAGATAGCGGTTAAATCTTATACTTTTATTCTAAAACTATAAAGCCCAGTCAACAAAAAACGCCAGTC
GCATCAGCCACTGGCGTTTT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTESTHLHPQEPSSTQNNKSIFNLPNNLTIARILMIPLFVAIAYWPPAMGIGMPAISDNVIAKVGMSDFSDSLLRHLLLT
GVFILAAITDWLDGYFARKLNVVSAFGRFLDPVADKLMVAAALIILVQWHPNIIMAIAAIVIISREIAVSALREWMAELG
KSTSVAVSYVGKLKTTFQMIAITVLLLNWESLETIGYVLMVAAVILTLWSMMIYLKAAWPYLKQSG

Sequences:

>Translated_226_residues
MTESTHLHPQEPSSTQNNKSIFNLPNNLTIARILMIPLFVAIAYWPPAMGIGMPAISDNVIAKVGMSDFSDSLLRHLLLT
GVFILAAITDWLDGYFARKLNVVSAFGRFLDPVADKLMVAAALIILVQWHPNIIMAIAAIVIISREIAVSALREWMAELG
KSTSVAVSYVGKLKTTFQMIAITVLLLNWESLETIGYVLMVAAVILTLWSMMIYLKAAWPYLKQSG
>Mature_225_residues
TESTHLHPQEPSSTQNNKSIFNLPNNLTIARILMIPLFVAIAYWPPAMGIGMPAISDNVIAKVGMSDFSDSLLRHLLLTG
VFILAAITDWLDGYFARKLNVVSAFGRFLDPVADKLMVAAALIILVQWHPNIIMAIAAIVIISREIAVSALREWMAELGK
STSVAVSYVGKLKTTFQMIAITVLLLNWESLETIGYVLMVAAVILTLWSMMIYLKAAWPYLKQSG

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=200, Percent_Identity=43.5, Blast_Score=149, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320059, Length=207, Percent_Identity=30.9178743961353, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 24934; Mature: 24803

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESTHLHPQEPSSTQNNKSIFNLPNNLTIARILMIPLFVAIAYWPPAMGIGMPAISDNV
CCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHH
IAKVGMSDFSDSLLRHLLLTGVFILAAITDWLDGYFARKLNVVSAFGRFLDPVADKLMVA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALIILVQWHPNIIMAIAAIVIISREIAVSALREWMAELGKSTSVAVSYVGKLKTTFQMI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AITVLLLNWESLETIGYVLMVAAVILTLWSMMIYLKAAWPYLKQSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TESTHLHPQEPSSTQNNKSIFNLPNNLTIARILMIPLFVAIAYWPPAMGIGMPAISDNV
CCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHH
IAKVGMSDFSDSLLRHLLLTGVFILAAITDWLDGYFARKLNVVSAFGRFLDPVADKLMVA
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALIILVQWHPNIIMAIAAIVIISREIAVSALREWMAELGKSTSVAVSYVGKLKTTFQMI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AITVLLLNWESLETIGYVLMVAAVILTLWSMMIYLKAAWPYLKQSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]