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The map label for this gene is dsbC [H]

Identifier: 93004863

GI number: 93004863

Start: 38643

End: 39686

Strand: Direct

Name: dsbC [H]

Synonym: Pcryo_0032

Alternate gene names: 93004863

Gene position: 38643-39686 (Clockwise)

Preceding gene: 93004862

Following gene: 93004865

Centisome position: 1.26

GC content: 44.92

Gene sequence:

>1044_bases
ATGTTGTTAGCAACCACTGCTTGCGCGCAGCCGAACACTGCCGATATGACCAATAAAACAGTCAGCCAAAAGGTTAACCA
CAGTGCCCAAGCTGGTCAGAATACGAAAGCTATTGGTACAGTCAGTAAATCTGTTGATAGCCGTTTGCGCCAATTGCTGA
CTCAAGCAGGTATCAAAACGCAGATAACCTCGATTGCACCCTCTAAATTACCCAATATGTATCAAGTCAATTTGGCTGAG
CAATTGCCACTGCATATTACTGAAGATGGTAAATATGTCATTCAAGGCGAGCTGCAAAAGAATCCAAGCAAGCGAGTAGT
AACCAAAACGCCAGCGCGTAGCACCAGCGCGCAAATAGGTAAGCCTGTCAGTGCCAGTATCAAATCTGACATATTGGCAA
ATATGGGCGCGCTTAAAAACATGAGTAACAAAACACCGTTCTTTTACACTGCAGTACCGGGTGTGATTTGGGGTGCGACT
TTAGAGGGCGTACCGTTCTTGTTATCAGATGACGCCCAGTACATCACCGATGGTGAGATATCAGTCATCGAAAATGGTCA
GTTTACTGGGCTTGATAACCGCTTTGAAAAGCTTAAAAATCAATCTGTCCTAACCACATTGGATACTAAGCAGTTAATTA
CCTATCCTGCCACTAGTGCTGAAAAAGCGGTGATTTACGTAGCAACGGATGTCAATTGCCCTTATTGCCGCAGATTACAT
AAGCAGATGCCGATGCTTAATGCCAAAGGCGTGACGATAAAAACTATTGGTTATCCGATTTATGAAGCGTCGCCTGAGCA
AATGCGCGGTATCTGGTGCCAAGGTAATGAGGAAAGTCGTCGTAAAGCGCTTGATCAGGCGATGCTACATGGCAAGATGA
CACCAGCGCCTGCATCTTGCAAAACTGATGATGTGGCAGGCAATCGTGAAAAAGCGGCAGGTTTAGCCGTCATGGCAACT
CCTGCTATTTATCGTGAAGATGGCGTATTGTTTCAAGCGAGTTTTGAGAGTCCTGAGTTTTTAGAATTCTTGGGAGTAAA
ATAA

Upstream 100 bases:

>100_bases
TATTAAATAGGCATGAGTGAATAACGATCATTATTAAAAACCAGATAGGACGGTCTCTGTGAAACTCCCTGTATTAAAAT
CCGCAAGTTTGATTGGTGTT

Downstream 100 bases:

>100_bases
GTCGTTGATATTTCTATAATAGTTATGATGGATATCATATTGAATAATGAATAAAAACCCGCCCTATGAATATAGCTCAT
AGGGCGGGTTTTTATTCATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLLATTACAQPNTADMTNKTVSQKVNHSAQAGQNTKAIGTVSKSVDSRLRQLLTQAGIKTQITSIAPSKLPNMYQVNLAE
QLPLHITEDGKYVIQGELQKNPSKRVVTKTPARSTSAQIGKPVSASIKSDILANMGALKNMSNKTPFFYTAVPGVIWGAT
LEGVPFLLSDDAQYITDGEISVIENGQFTGLDNRFEKLKNQSVLTTLDTKQLITYPATSAEKAVIYVATDVNCPYCRRLH
KQMPMLNAKGVTIKTIGYPIYEASPEQMRGIWCQGNEESRRKALDQAMLHGKMTPAPASCKTDDVAGNREKAAGLAVMAT
PAIYREDGVLFQASFESPEFLEFLGVK

Sequences:

>Translated_347_residues
MLLATTACAQPNTADMTNKTVSQKVNHSAQAGQNTKAIGTVSKSVDSRLRQLLTQAGIKTQITSIAPSKLPNMYQVNLAE
QLPLHITEDGKYVIQGELQKNPSKRVVTKTPARSTSAQIGKPVSASIKSDILANMGALKNMSNKTPFFYTAVPGVIWGAT
LEGVPFLLSDDAQYITDGEISVIENGQFTGLDNRFEKLKNQSVLTTLDTKQLITYPATSAEKAVIYVATDVNCPYCRRLH
KQMPMLNAKGVTIKTIGYPIYEASPEQMRGIWCQGNEESRRKALDQAMLHGKMTPAPASCKTDDVAGNREKAAGLAVMAT
PAIYREDGVLFQASFESPEFLEFLGVK
>Mature_347_residues
MLLATTACAQPNTADMTNKTVSQKVNHSAQAGQNTKAIGTVSKSVDSRLRQLLTQAGIKTQITSIAPSKLPNMYQVNLAE
QLPLHITEDGKYVIQGELQKNPSKRVVTKTPARSTSAQIGKPVSASIKSDILANMGALKNMSNKTPFFYTAVPGVIWGAT
LEGVPFLLSDDAQYITDGEISVIENGQFTGLDNRFEKLKNQSVLTTLDTKQLITYPATSAEKAVIYVATDVNCPYCRRLH
KQMPMLNAKGVTIKTIGYPIYEASPEQMRGIWCQGNEESRRKALDQAMLHGKMTPAPASCKTDDVAGNREKAAGLAVMAT
PAIYREDGVLFQASFESPEFLEFLGVK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=177, Percent_Identity=33.8983050847458, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 37735; Mature: 37735

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLATTACAQPNTADMTNKTVSQKVNHSAQAGQNTKAIGTVSKSVDSRLRQLLTQAGIKT
CEEEECCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCE
QITSIAPSKLPNMYQVNLAEQLPLHITEDGKYVIQGELQKNPSKRVVTKTPARSTSAQIG
EHHHCCHHHCCCEEEECHHHHCCEEEECCCCEEEEEECCCCCCCCEEEECCCCCCHHHCC
KPVSASIKSDILANMGALKNMSNKTPFFYTAVPGVIWGATLEGVPFLLSDDAQYITDGEI
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCHHCCCCEEEECCCCEEECCCE
SVIENGQFTGLDNRFEKLKNQSVLTTLDTKQLITYPATSAEKAVIYVATDVNCPYCRRLH
EEEECCCCCCCHHHHHHHCCCCEEEEECCHHEEEECCCCCCCEEEEEEECCCCHHHHHHH
KQMPMLNAKGVTIKTIGYPIYEASPEQMRGIWCQGNEESRRKALDQAMLHGKMTPAPASC
HHCCCCCCCCCEEEECCCCEECCCHHHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
KTDDVAGNREKAAGLAVMATPAIYREDGVLFQASFESPEFLEFLGVK
CCCCCCCCCHHHCCEEEEECCCEEECCCEEEEECCCCCHHHHHHCCC
>Mature Secondary Structure
MLLATTACAQPNTADMTNKTVSQKVNHSAQAGQNTKAIGTVSKSVDSRLRQLLTQAGIKT
CEEEECCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCE
QITSIAPSKLPNMYQVNLAEQLPLHITEDGKYVIQGELQKNPSKRVVTKTPARSTSAQIG
EHHHCCHHHCCCEEEECHHHHCCEEEECCCCEEEEEECCCCCCCCEEEECCCCCCHHHCC
KPVSASIKSDILANMGALKNMSNKTPFFYTAVPGVIWGATLEGVPFLLSDDAQYITDGEI
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCHHCCCCEEEECCCCEEECCCE
SVIENGQFTGLDNRFEKLKNQSVLTTLDTKQLITYPATSAEKAVIYVATDVNCPYCRRLH
EEEECCCCCCCHHHHHHHCCCCEEEEECCHHEEEECCCCCCCEEEEEEECCCCHHHHHHH
KQMPMLNAKGVTIKTIGYPIYEASPEQMRGIWCQGNEESRRKALDQAMLHGKMTPAPASC
HHCCCCCCCCCEEEECCCCEECCCHHHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCC
KTDDVAGNREKAAGLAVMATPAIYREDGVLFQASFESPEFLEFLGVK
CCCCCCCCCHHHCCEEEEECCCEEECCCEEEEECCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]