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The map label for this gene is lip3 [H]

Identifier: 93004854

GI number: 93004854

Start: 28605

End: 29552

Strand: Direct

Name: lip3 [H]

Synonym: Pcryo_0023

Alternate gene names: 93004854

Gene position: 28605-29552 (Clockwise)

Preceding gene: 93004852

Following gene: 93004856

Centisome position: 0.93

GC content: 43.99

Gene sequence:

>948_bases
ATGCTATTAAAACGCCTAGGCCTTGCCACTTTGTTAAGCTTTTCAGTCGTTGGTTGTACCACAGCGCCCAATACCTTGGC
GATAAATACCACCCAAAAGATTATTCAGTATGAACGCTCAAAATCAGACCTTACGACTCAGTCATTTACGTTAAGCTCTG
GCGATAAAATAGTCTATGCAGAAAACGGTAATGTCGCGGGCGAGCCTTTATTATTGGTTCATGGCTTTGGCGGTAATAAA
GACAACTTTACCCGTATCGCTCGGCAGTTAGAGAACTATAATCTGATCATTCCTGATTTGCTCGGCTTTGGTGACTCTAG
TAAACCGATGGCGGCTGACTATCACTCGGAGGCGCAAGCGACGCGCTTACACGAGCTACTGCAAGCTAAAGGCTTGGCAT
CTAGCATTCATGTCGGTGGCAACTCAATGGGTGGCGCTATCAGTGTTGCTTATGCTGCGAAGTATCCTAAAGAAGTCAAA
AGTCTGTGGCTAATAGATAGTGCGGGCTTTTGGTCAGCGGGTGTGCCGAAATCCTTAGAAAGTGCAACTCTCGAGAACAA
TCCGCTATTGGTCGATAAGAAGGAAGACTTTTATGCTATGTATGACTTTGTTATGTCTAAGCCGCCTTATATTCCTAAGT
CTGTAAAAGCCGTATTCGCGCAAGAGCGTATCGCTAATAAAGCATTAGAATCCAAAATACTCGCGCAAATAGTTGAAGAC
AATGTTGAGCAGCGTGCCAAGGTTATCACTGAATATAATATTCCAACACTAGTCGTTTGGGGTGAGGAGGATAAGGTCAT
CAAGCCTGAAACCGTGACGCTAATAAAAGAAATCATCCCACAATCACAAGTGATTACGATGCCAAAAATCGGTCATGTAC
CGATGATAGAAGCGGTGAAAGATACGGCGAATGATTATAAAGCGTTTCGTGAAGGGTTAAAGAACTAG

Upstream 100 bases:

>100_bases
GGGTGGTTATTATAAGTTCTTAAACTTAAAATACTCTTGTGCTAGGATGATGCTTTTTGCTTCTTACTTCATTTTTCTAG
TTTTCAAAAAGGATATTTCG

Downstream 100 bases:

>100_bases
TCATTTACATATGATATTTTAAGGCGTAAATGATCCAACGTTTGATTAGATATGAGCTGTAGTCAGTCCTAAATAAAAGA
AATACAAACATTATAAGGTG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MLLKRLGLATLLSFSVVGCTTAPNTLAINTTQKIIQYERSKSDLTTQSFTLSSGDKIVYAENGNVAGEPLLLVHGFGGNK
DNFTRIARQLENYNLIIPDLLGFGDSSKPMAADYHSEAQATRLHELLQAKGLASSIHVGGNSMGGAISVAYAAKYPKEVK
SLWLIDSAGFWSAGVPKSLESATLENNPLLVDKKEDFYAMYDFVMSKPPYIPKSVKAVFAQERIANKALESKILAQIVED
NVEQRAKVITEYNIPTLVVWGEEDKVIKPETVTLIKEIIPQSQVITMPKIGHVPMIEAVKDTANDYKAFREGLKN

Sequences:

>Translated_315_residues
MLLKRLGLATLLSFSVVGCTTAPNTLAINTTQKIIQYERSKSDLTTQSFTLSSGDKIVYAENGNVAGEPLLLVHGFGGNK
DNFTRIARQLENYNLIIPDLLGFGDSSKPMAADYHSEAQATRLHELLQAKGLASSIHVGGNSMGGAISVAYAAKYPKEVK
SLWLIDSAGFWSAGVPKSLESATLENNPLLVDKKEDFYAMYDFVMSKPPYIPKSVKAVFAQERIANKALESKILAQIVED
NVEQRAKVITEYNIPTLVVWGEEDKVIKPETVTLIKEIIPQSQVITMPKIGHVPMIEAVKDTANDYKAFREGLKN
>Mature_315_residues
MLLKRLGLATLLSFSVVGCTTAPNTLAINTTQKIIQYERSKSDLTTQSFTLSSGDKIVYAENGNVAGEPLLLVHGFGGNK
DNFTRIARQLENYNLIIPDLLGFGDSSKPMAADYHSEAQATRLHELLQAKGLASSIHVGGNSMGGAISVAYAAKYPKEVK
SLWLIDSAGFWSAGVPKSLESATLENNPLLVDKKEDFYAMYDFVMSKPPYIPKSVKAVFAQERIANKALESKILAQIVED
NVEQRAKVITEYNIPTLVVWGEEDKVIKPETVTLIKEIIPQSQVITMPKIGHVPMIEAVKDTANDYKAFREGLKN

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=259, Percent_Identity=24.7104247104247, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 34563; Mature: 34563

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKRLGLATLLSFSVVGCTTAPNTLAINTTQKIIQYERSKSDLTTQSFTLSSGDKIVYA
CCHHHHHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHCCCCCCEEEEEECCCCEEEEE
ENGNVAGEPLLLVHGFGGNKDNFTRIARQLENYNLIIPDLLGFGDSSKPMAADYHSEAQA
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEHHHHCCCCCCCCCCCCHHHHHHH
TRLHELLQAKGLASSIHVGGNSMGGAISVAYAAKYPKEVKSLWLIDSAGFWSAGVPKSLE
HHHHHHHHHCCCHHEEEECCCCCCCEEEEHHHHHCHHHHHHEEEEECCCCCCCCCCCHHH
SATLENNPLLVDKKEDFYAMYDFVMSKPPYIPKSVKAVFAQERIANKALESKILAQIVED
HCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVEQRAKVITEYNIPTLVVWGEEDKVIKPETVTLIKEIIPQSQVITMPKIGHVPMIEAVK
HHHHHHHHHEECCCCEEEEECCCCCEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHH
DTANDYKAFREGLKN
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLKRLGLATLLSFSVVGCTTAPNTLAINTTQKIIQYERSKSDLTTQSFTLSSGDKIVYA
CCHHHHHHHHHHHHHHHEECCCCCEEEECHHHHHHHHHHCCCCCCEEEEEECCCCEEEEE
ENGNVAGEPLLLVHGFGGNKDNFTRIARQLENYNLIIPDLLGFGDSSKPMAADYHSEAQA
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEHHHHCCCCCCCCCCCCHHHHHHH
TRLHELLQAKGLASSIHVGGNSMGGAISVAYAAKYPKEVKSLWLIDSAGFWSAGVPKSLE
HHHHHHHHHCCCHHEEEECCCCCCCEEEEHHHHHCHHHHHHEEEEECCCCCCCCCCCHHH
SATLENNPLLVDKKEDFYAMYDFVMSKPPYIPKSVKAVFAQERIANKALESKILAQIVED
HCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVEQRAKVITEYNIPTLVVWGEEDKVIKPETVTLIKEIIPQSQVITMPKIGHVPMIEAVK
HHHHHHHHHEECCCCEEEEECCCCCEECCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHH
DTANDYKAFREGLKN
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2001407 [H]