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The map label for this gene is garD [H]

Identifier: 92113889

GI number: 92113889

Start: 2010700

End: 2011869

Strand: Direct

Name: garD [H]

Synonym: Csal_1766

Alternate gene names: 92113889

Gene position: 2010700-2011869 (Clockwise)

Preceding gene: 92113888

Following gene: 92113890

Centisome position: 54.39

GC content: 64.02

Gene sequence:

>1170_bases
ATGGAACTCAAGGGACGCACTTTCCTCGGCTATCGGCGCGACAACGGCCGTGTCGGCATCCGCAATCACGTCATCGTGCT
GCCGGTGGACGACATTTCGAATGCCGCGGCGGAAGCGGTGGCCAACAATATCAAGGGCACGCTGGCATTGCCGCATCCCT
ATGGCCGGTTGCAGTTCGGCGCCGACCTGGATTTGCACTTCCGCACGCTGATCGGCACCGGCTGCAATCCGAACGTCGCC
GCGGTGATCGTGATCGGCATCGAGCCAGGCTGGACGGGGAAGGTGGTCGACGGCATCCGCGCCACCGGCAAGCCGGTGGA
AGGCTTCTGGATCGAGCAGAACGGCGATCACAACACCATCGCCAATGCCTCGCGCAAGGCCCGCGAATTCGTGCAGTACG
CCAGCGAGCTGCAGCGCGAACCCTGCGACGTCAGCGAGCTATGGGTCTCCACCAAGTGCGGTGAGTCCGACACCACCTCC
GGATGCGGCGCCAACCCCACCGTCGGCGAAGCCTTCGACAAGCTCTACGAGCAGGGCTGCACGCTGGTGTTCGGCGAGAC
TTCCGAGCTCACCGGCGGCGAGCACCTGGTCGCGGCGCGTTGCGCCAACGATGACGTGCGCGAACGGTTCCAGGCGATGT
TCGATCGCTACAGCGCGATGATCGACCGTCACAAGACCAGCGATCTTTCCGAATCGCAGCCCACCAAGGGCAACATCGAG
GGCGGATTGACCACCATCGAGGAAAAGGCGCTGGGCAACATTCAGAAGATCGGCAAGCGCTGCCGGGTCGATGGCGTGCT
CGACAAGGCCGAAACCCCCACCGGACCGGGCCTGTGGTTCATGGACTCCTCCTCGGCGGCGGCCGAGATGGTCACGCTGT
GCGCGGCCTCGGGGTACGTGGCGCATTTCTTCCCGACGGGGCAGGGCAACGTAATCGGCAACCCGATCCTGCCGGTGATC
AAGCTCTGCGCCAACCCGCGCACGGTACGCACGATGAGCGAGCATATCGACGTCGATGTCTCGGGGGTCCTGCGTCGGGA
AATCAACCTTCAGGAGGCGGGGGATCAACTGCTCGAGATGCTGCTGCGCACGGCCAACGGACGGCATACCAATGCCGAGG
CGTTGGGCCATAGGGAATTCGTGCTGACGCGCCTCTACGAAAGTGCATGA

Upstream 100 bases:

>100_bases
CGGTCATCAAGTACAGCGTCGATATCGGCCGGGTGGTGCAGTCGATCCGCCAGGGCGAGCACGTTCACGTTCACAATGTC
AAAACCAAGAGGTGGTAAGC

Downstream 100 bases:

>100_bases
GGCTAAAGAAGAGTGCCGCCGGACGATCGTCGAATGCTAATACGGTCGAGGCTGTGTACCGGCATGTCCATCACGGAAGC
AGCAAGGTAGCGACGCGTAT

Product: Altronate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MELKGRTFLGYRRDNGRVGIRNHVIVLPVDDISNAAAEAVANNIKGTLALPHPYGRLQFGADLDLHFRTLIGTGCNPNVA
AVIVIGIEPGWTGKVVDGIRATGKPVEGFWIEQNGDHNTIANASRKAREFVQYASELQREPCDVSELWVSTKCGESDTTS
GCGANPTVGEAFDKLYEQGCTLVFGETSELTGGEHLVAARCANDDVRERFQAMFDRYSAMIDRHKTSDLSESQPTKGNIE
GGLTTIEEKALGNIQKIGKRCRVDGVLDKAETPTGPGLWFMDSSSAAAEMVTLCAASGYVAHFFPTGQGNVIGNPILPVI
KLCANPRTVRTMSEHIDVDVSGVLRREINLQEAGDQLLEMLLRTANGRHTNAEALGHREFVLTRLYESA

Sequences:

>Translated_389_residues
MELKGRTFLGYRRDNGRVGIRNHVIVLPVDDISNAAAEAVANNIKGTLALPHPYGRLQFGADLDLHFRTLIGTGCNPNVA
AVIVIGIEPGWTGKVVDGIRATGKPVEGFWIEQNGDHNTIANASRKAREFVQYASELQREPCDVSELWVSTKCGESDTTS
GCGANPTVGEAFDKLYEQGCTLVFGETSELTGGEHLVAARCANDDVRERFQAMFDRYSAMIDRHKTSDLSESQPTKGNIE
GGLTTIEEKALGNIQKIGKRCRVDGVLDKAETPTGPGLWFMDSSSAAAEMVTLCAASGYVAHFFPTGQGNVIGNPILPVI
KLCANPRTVRTMSEHIDVDVSGVLRREINLQEAGDQLLEMLLRTANGRHTNAEALGHREFVLTRLYESA
>Mature_389_residues
MELKGRTFLGYRRDNGRVGIRNHVIVLPVDDISNAAAEAVANNIKGTLALPHPYGRLQFGADLDLHFRTLIGTGCNPNVA
AVIVIGIEPGWTGKVVDGIRATGKPVEGFWIEQNGDHNTIANASRKAREFVQYASELQREPCDVSELWVSTKCGESDTTS
GCGANPTVGEAFDKLYEQGCTLVFGETSELTGGEHLVAARCANDDVRERFQAMFDRYSAMIDRHKTSDLSESQPTKGNIE
GGLTTIEEKALGNIQKIGKRCRVDGVLDKAETPTGPGLWFMDSSSAAAEMVTLCAASGYVAHFFPTGQGNVIGNPILPVI
KLCANPRTVRTMSEHIDVDVSGVLRREINLQEAGDQLLEMLLRTANGRHTNAEALGHREFVLTRLYESA

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=394, Percent_Identity=30.2030456852792, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789475, Length=394, Percent_Identity=29.9492385786802, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 42228; Mature: 42228

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKGRTFLGYRRDNGRVGIRNHVIVLPVDDISNAAAEAVANNIKGTLALPHPYGRLQFG
CCCCCCEEEEEECCCCEEEECCCEEEEECCCHHHHHHHHHHHCCCCEEECCCCCCCEEEC
ADLDLHFRTLIGTGCNPNVAAVIVIGIEPGWTGKVVDGIRATGKPVEGFWIEQNGDHNTI
CCCCEEEHEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHH
ANASRKAREFVQYASELQREPCDVSELWVSTKCGESDTTSGCGANPTVGEAFDKLYEQGC
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
TLVFGETSELTGGEHLVAARCANDDVRERFQAMFDRYSAMIDRHKTSDLSESQPTKGNIE
EEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GGLTTIEEKALGNIQKIGKRCRVDGVLDKAETPTGPGLWFMDSSSAAAEMVTLCAASGYV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCE
AHFFPTGQGNVIGNPILPVIKLCANPRTVRTMSEHIDVDVSGVLRREINLQEAGDQLLEM
EEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
LLRTANGRHTNAEALGHREFVLTRLYESA
HHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELKGRTFLGYRRDNGRVGIRNHVIVLPVDDISNAAAEAVANNIKGTLALPHPYGRLQFG
CCCCCCEEEEEECCCCEEEECCCEEEEECCCHHHHHHHHHHHCCCCEEECCCCCCCEEEC
ADLDLHFRTLIGTGCNPNVAAVIVIGIEPGWTGKVVDGIRATGKPVEGFWIEQNGDHNTI
CCCCEEEHEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHH
ANASRKAREFVQYASELQREPCDVSELWVSTKCGESDTTSGCGANPTVGEAFDKLYEQGC
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
TLVFGETSELTGGEHLVAARCANDDVRERFQAMFDRYSAMIDRHKTSDLSESQPTKGNIE
EEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GGLTTIEEKALGNIQKIGKRCRVDGVLDKAETPTGPGLWFMDSSSAAAEMVTLCAASGYV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCE
AHFFPTGQGNVIGNPILPVIKLCANPRTVRTMSEHIDVDVSGVLRREINLQEAGDQLLEM
EEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHH
LLRTANGRHTNAEALGHREFVLTRLYESA
HHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 2407727; 9772162; 10762278 [H]