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The map label for this gene is udg [H]

Identifier: 92113884

GI number: 92113884

Start: 2006066

End: 2007406

Strand: Direct

Name: udg [H]

Synonym: Csal_1761

Alternate gene names: 92113884

Gene position: 2006066-2007406 (Clockwise)

Preceding gene: 92113883

Following gene: 92113886

Centisome position: 54.27

GC content: 65.25

Gene sequence:

>1341_bases
ATGAAGATCAGTATCTTCGGTACGGGATACGTGGGCCTGGTCACCGGGACTTGCCTGGCGGACGTGGGGCACGAGGTCAT
GTGCATGGACGTCGACGCTGACAAGATCGCCCGCCTCGAGCGCGGCGAGATCCCCATCTACGAGCCGGGGCTGGACGCCA
TGGTGCGTCAGAACGTGAGCGAGGGCCGGCTGCGGTTCACCACCGATGCCGCCACCGCCGTGGGCTTCGCGCCGTTGCAG
TTCATCGCCGTGGGCACGCCCCCGGACGAGGATGGCAGTGCCGATTTGCAGTACGTGCTGGCCGTGGCGCGCAGCATCGG
CCAGCACATGCAGGACGACAAGGTCGTCGTCGACAAGTCGACCGTGCCGGTGGGCACTGCGGACAAGGTGCGCGCCGCCG
TTCAGCAGGAGCTCGATGCCCGCGACGCTGCGCTCACCGTGGATGTCTGCTCCAATCCCGAGTTCTTGAAGGAAGGCGCC
GCCATCGAGGACTTCACGCATGGCGCACGGATCATCGTGGGCACCGATGCCGAGCGGGTGCGCGAGATCATGCGTGAATG
CTACGGTCCCTATAACCGGCACCATGAGAAGTTGATGTTCATGGATATCCGCAGCGCCGAGCTGACCAAATACGCGGCCA
ACGCCATGCTCGCCACCAAGATCAGCTTCATGAACGAGATCGCCAATCTCGCGGAGCGTCTCGGGGCGGACATCGAACAG
GTGCGGCGCGGCATCGGCTCGGACCCGCGCATCGGGTATCACTTCATCTATCCGGGATGCGGCTACGGCGGCTCCTGCTT
TCCCAAGGACGTGCAGGCACTGGCGCGCACCGCCGGCGAGATCGGCTACCATGCCGAGCTACTCGAAGCGGTCGAAGGCG
TCAACCAGCGTCAGAAGGCCACCCTGTTCGCCAAGCTCTCGCAAGCCTTCGACGGCGATCTGGCCGGCAAGACCATCGCG
CTCTGGGGGCTGGCCTTCAAGCCCAACACCGACGACATGCGCGAGGCCCCGAGTCGCGCCTTGATGGAAGCGCTGTGGGA
ATGCGGCGCCCGGGTGCAGGCCTTCGACCCGGAGGCCATGGACGAATGCCGGCGGATCTACGGCAAGCGCGACGACCTGG
CACTGGTCGATAATCGCGAGCAGGCCATCGAGGGGGCCGACGCCCTGGTGATCTGTACCGAATGGAAGGCGTTCTGCAGC
GTGGATTTCGCCTGGCTCAAGCAGTCGCTGAGCACACCGGTGGTCGTCGACGGCCGCAACCTGTTCGATCCGCAGGCGGT
CAAGCGCGCGGGATTGTTGTACTTCGCGGTGGGGCGCGGGGATTCCTTGCGTACGCCATGA

Upstream 100 bases:

>100_bases
GTCGACGAGGGCGTGGCGCGCTTCGTCGAGTGGTACCGCAGCTTTCACGGGATTTGATGCCCACGATTTTTTGGTTAACG
AGCGTAAAGGACGACATACG

Downstream 100 bases:

>100_bases
GCCCCGCTCACGACGAAACGGCGCCTTCGGGCGCCGTTTTGCGTTGGGCTCAACGTTCAGTGCATGAGCCAGGGCGTCAC
CCAGCCACCGCCGATCAGCA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKISIFGTGYVGLVTGTCLADVGHEVMCMDVDADKIARLERGEIPIYEPGLDAMVRQNVSEGRLRFTTDAATAVGFAPLQ
FIAVGTPPDEDGSADLQYVLAVARSIGQHMQDDKVVVDKSTVPVGTADKVRAAVQQELDARDAALTVDVCSNPEFLKEGA
AIEDFTHGARIIVGTDAERVREIMRECYGPYNRHHEKLMFMDIRSAELTKYAANAMLATKISFMNEIANLAERLGADIEQ
VRRGIGSDPRIGYHFIYPGCGYGGSCFPKDVQALARTAGEIGYHAELLEAVEGVNQRQKATLFAKLSQAFDGDLAGKTIA
LWGLAFKPNTDDMREAPSRALMEALWECGARVQAFDPEAMDECRRIYGKRDDLALVDNREQAIEGADALVICTEWKAFCS
VDFAWLKQSLSTPVVVDGRNLFDPQAVKRAGLLYFAVGRGDSLRTP

Sequences:

>Translated_446_residues
MKISIFGTGYVGLVTGTCLADVGHEVMCMDVDADKIARLERGEIPIYEPGLDAMVRQNVSEGRLRFTTDAATAVGFAPLQ
FIAVGTPPDEDGSADLQYVLAVARSIGQHMQDDKVVVDKSTVPVGTADKVRAAVQQELDARDAALTVDVCSNPEFLKEGA
AIEDFTHGARIIVGTDAERVREIMRECYGPYNRHHEKLMFMDIRSAELTKYAANAMLATKISFMNEIANLAERLGADIEQ
VRRGIGSDPRIGYHFIYPGCGYGGSCFPKDVQALARTAGEIGYHAELLEAVEGVNQRQKATLFAKLSQAFDGDLAGKTIA
LWGLAFKPNTDDMREAPSRALMEALWECGARVQAFDPEAMDECRRIYGKRDDLALVDNREQAIEGADALVICTEWKAFCS
VDFAWLKQSLSTPVVVDGRNLFDPQAVKRAGLLYFAVGRGDSLRTP
>Mature_446_residues
MKISIFGTGYVGLVTGTCLADVGHEVMCMDVDADKIARLERGEIPIYEPGLDAMVRQNVSEGRLRFTTDAATAVGFAPLQ
FIAVGTPPDEDGSADLQYVLAVARSIGQHMQDDKVVVDKSTVPVGTADKVRAAVQQELDARDAALTVDVCSNPEFLKEGA
AIEDFTHGARIIVGTDAERVREIMRECYGPYNRHHEKLMFMDIRSAELTKYAANAMLATKISFMNEIANLAERLGADIEQ
VRRGIGSDPRIGYHFIYPGCGYGGSCFPKDVQALARTAGEIGYHAELLEAVEGVNQRQKATLFAKLSQAFDGDLAGKTIA
LWGLAFKPNTDDMREAPSRALMEALWECGARVQAFDPEAMDECRRIYGKRDDLALVDNREQAIEGADALVICTEWKAFCS
VDFAWLKQSLSTPVVVDGRNLFDPQAVKRAGLLYFAVGRGDSLRTP

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=447, Percent_Identity=34.4519015659955, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI296040438, Length=349, Percent_Identity=34.3839541547278, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI296040443, Length=294, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1788340, Length=360, Percent_Identity=28.8888888888889, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI48994968, Length=424, Percent_Identity=28.3018867924528, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=33.0472103004292, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI17136908, Length=468, Percent_Identity=33.1196581196581, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48773; Mature: 48773

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISIFGTGYVGLVTGTCLADVGHEVMCMDVDADKIARLERGEIPIYEPGLDAMVRQNVS
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHCCCC
EGRLRFTTDAATAVGFAPLQFIAVGTPPDEDGSADLQYVLAVARSIGQHMQDDKVVVDKS
CCCEEEEECHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
TVPVGTADKVRAAVQQELDARDAALTVDVCSNPEFLKEGAAIEDFTHGARIIVGTDAERV
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCHHHHCCCCEEEEECCHHHH
REIMRECYGPYNRHHEKLMFMDIRSAELTKYAANAMLATKISFMNEIANLAERLGADIEQ
HHHHHHHCCCCHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRRGIGSDPRIGYHFIYPGCGYGGSCFPKDVQALARTAGEIGYHAELLEAVEGVNQRQKA
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHH
TLFAKLSQAFDGDLAGKTIALWGLAFKPNTDDMREAPSRALMEALWECGARVQAFDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHH
DECRRIYGKRDDLALVDNREQAIEGADALVICTEWKAFCSVDFAWLKQSLSTPVVVDGRN
HHHHHHHCCCCCEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEECCCC
LFDPQAVKRAGLLYFAVGRGDSLRTP
CCCHHHHHHCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKISIFGTGYVGLVTGTCLADVGHEVMCMDVDADKIARLERGEIPIYEPGLDAMVRQNVS
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHCCCC
EGRLRFTTDAATAVGFAPLQFIAVGTPPDEDGSADLQYVLAVARSIGQHMQDDKVVVDKS
CCCEEEEECHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECC
TVPVGTADKVRAAVQQELDARDAALTVDVCSNPEFLKEGAAIEDFTHGARIIVGTDAERV
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCHHHHCCCCEEEEECCHHHH
REIMRECYGPYNRHHEKLMFMDIRSAELTKYAANAMLATKISFMNEIANLAERLGADIEQ
HHHHHHHCCCCHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRRGIGSDPRIGYHFIYPGCGYGGSCFPKDVQALARTAGEIGYHAELLEAVEGVNQRQKA
HHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHH
TLFAKLSQAFDGDLAGKTIALWGLAFKPNTDDMREAPSRALMEALWECGARVQAFDPEAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHH
DECRRIYGKRDDLALVDNREQAIEGADALVICTEWKAFCSVDFAWLKQSLSTPVVVDGRN
HHHHHHHCCCCCEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEECCCC
LFDPQAVKRAGLLYFAVGRGDSLRTP
CCCHHHHHHCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]