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The map label for this gene is lepB [H]

Identifier: 92113754

GI number: 92113754

Start: 1852991

End: 1853794

Strand: Direct

Name: lepB [H]

Synonym: Csal_1630

Alternate gene names: 92113754

Gene position: 1852991-1853794 (Clockwise)

Preceding gene: 92113753

Following gene: 92113755

Centisome position: 50.13

GC content: 62.56

Gene sequence:

>804_bases
ATGGATTTTTCGTTGTTGCTGGTGCTGGCCGTGGCCATCACCGGCATTGTCTGGCTGTTGGATATCGTATGGTGGCGGCG
TGCGCGTCGCGCCCGGCTGGCCACGGCCGAGTCGCAGGTCGACGGTGAGCTGGATGCCGCGACGCGCGGCAAGCTGGCCA
AGGAACCCTGGCCGGTGGATTATGCGCGCTCTTTCTTTCCGGTGCTGTTGATCGTGCTGGTGCTGCGCAGCTTCGTGGTC
GAGCCGTTTCAGATTCCTTCCGGCTCGATGCGTCCCACGCTCAAGGTCGGTGACTTCATCCTGGTCAACAAGTTCACCTA
CGGGCTGCGGTTGCCGGTAATCAACACGGAAATCCTCGACCTCGGCGAGCCGGAACGCGGCGACATCATGGTGTTCCGTT
TTCCGGACGACCCTTCGGTCAACTTCATCAAGCGCGTGGTCGGCCTGCCGGGCGATCGCATTCGCTACGAAGACAAGCAG
CTTTACGTCAACGGCCAGCCAGTCGCCAAGTCGGTGACCGACGACGACGCCGATGACGCGCCCGGCGAGCGGCAATTCGA
GGAACGCCTGGGGGATGTCGCCCATGCCATCTACAACAATCCGCAGGACCCCGGCCCGCAGATGCGCGAGGTCGTGGTGC
CGGACGGGCAGTACTTCATGATGGGCGACAACCGCGACCATTCCAACGACAGCCGCTACTGGGGCTTCGTGCCGGAAGAG
AACATCGTGGGCGAGGCCTTTGCCGTGTGGATGCACTGGGATGGCGGTTTGCCGAGTTTCTCCAGTGTCAGGCTCCTCGA
ATGA

Upstream 100 bases:

>100_bases
AGAAAGCAGGCAAAAAGCGCATGAAGCAAGTCGGCAAGGTGGAGATTCCCCAGGATGCCTTCCTCGCCGTCCTCAAGATG
AATGACTAGGAATCGTAGCC

Downstream 100 bases:

>100_bases
CCCGGACTCTCGAATGACTCATACTGACGTTCGCATGACCCATACTAGGGGAGAGCGACGCTCTCCGACGCGTTATCAAG
AACAGATGAAAAAGGCAGTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MDFSLLLVLAVAITGIVWLLDIVWWRRARRARLATAESQVDGELDAATRGKLAKEPWPVDYARSFFPVLLIVLVLRSFVV
EPFQIPSGSMRPTLKVGDFILVNKFTYGLRLPVINTEILDLGEPERGDIMVFRFPDDPSVNFIKRVVGLPGDRIRYEDKQ
LYVNGQPVAKSVTDDDADDAPGERQFEERLGDVAHAIYNNPQDPGPQMREVVVPDGQYFMMGDNRDHSNDSRYWGFVPEE
NIVGEAFAVWMHWDGGLPSFSSVRLLE

Sequences:

>Translated_267_residues
MDFSLLLVLAVAITGIVWLLDIVWWRRARRARLATAESQVDGELDAATRGKLAKEPWPVDYARSFFPVLLIVLVLRSFVV
EPFQIPSGSMRPTLKVGDFILVNKFTYGLRLPVINTEILDLGEPERGDIMVFRFPDDPSVNFIKRVVGLPGDRIRYEDKQ
LYVNGQPVAKSVTDDDADDAPGERQFEERLGDVAHAIYNNPQDPGPQMREVVVPDGQYFMMGDNRDHSNDSRYWGFVPEE
NIVGEAFAVWMHWDGGLPSFSSVRLLE
>Mature_267_residues
MDFSLLLVLAVAITGIVWLLDIVWWRRARRARLATAESQVDGELDAATRGKLAKEPWPVDYARSFFPVLLIVLVLRSFVV
EPFQIPSGSMRPTLKVGDFILVNKFTYGLRLPVINTEILDLGEPERGDIMVFRFPDDPSVNFIKRVVGLPGDRIRYEDKQ
LYVNGQPVAKSVTDDDADDAPGERQFEERLGDVAHAIYNNPQDPGPQMREVVVPDGQYFMMGDNRDHSNDSRYWGFVPEE
NIVGEAFAVWMHWDGGLPSFSSVRLLE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=301, Percent_Identity=42.1926910299003, Blast_Score=231, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30268; Mature: 30268

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLLLVLAVAITGIVWLLDIVWWRRARRARLATAESQVDGELDAATRGKLAKEPWPVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHH
YARSFFPVLLIVLVLRSFVVEPFQIPSGSMRPTLKVGDFILVNKFTYGLRLPVINTEILD
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEECCEEEEEEEECEEECCEECCCEEE
LGEPERGDIMVFRFPDDPSVNFIKRVVGLPGDRIRYEDKQLYVNGQPVAKSVTDDDADDA
CCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCCCCC
PGERQFEERLGDVAHAIYNNPQDPGPQMREVVVPDGQYFMMGDNRDHSNDSRYWGFVPEE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCEECCCCCC
NIVGEAFAVWMHWDGGLPSFSSVRLLE
CCCCCEEEEEEEECCCCCCCCCEEECC
>Mature Secondary Structure
MDFSLLLVLAVAITGIVWLLDIVWWRRARRARLATAESQVDGELDAATRGKLAKEPWPVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHH
YARSFFPVLLIVLVLRSFVVEPFQIPSGSMRPTLKVGDFILVNKFTYGLRLPVINTEILD
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEECCEEEEEEEECEEECCEECCCEEE
LGEPERGDIMVFRFPDDPSVNFIKRVVGLPGDRIRYEDKQLYVNGQPVAKSVTDDDADDA
CCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCCCCCCC
PGERQFEERLGDVAHAIYNNPQDPGPQMREVVVPDGQYFMMGDNRDHSNDSRYWGFVPEE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCEECCCCCC
NIVGEAFAVWMHWDGGLPSFSSVRLLE
CCCCCEEEEEEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1546969 [H]