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The map label for this gene is fabD [H]

Identifier: 92113724

GI number: 92113724

Start: 1821245

End: 1822204

Strand: Direct

Name: fabD [H]

Synonym: Csal_1600

Alternate gene names: 92113724

Gene position: 1821245-1822204 (Clockwise)

Preceding gene: 92113723

Following gene: 92113725

Centisome position: 49.27

GC content: 66.88

Gene sequence:

>960_bases
ATGACTCAATCCCTCGCCCTTGTCTTTCCAGGGCAGGGCTCCCAGCAGGTCGGCATGCTGAGGGAGCTGGCCGAGCGCTA
CAGCGTGGTGCGGACCACGTTCGACGAAGCCTCGGGCGCGCTGGGTTACGATCTCTGGAAAGTGGTCCAGGAAGGCCCGG
AAAGCACCTTGAACACCACCGCCTGCACGCAGCCGGCACTATTGACGTCCAGCGTGGCGATCTGGCGTGTCTGGCAGGAG
CTGGAAGGCCCGCGCCCGCTGGTCATGGCCGGCCACAGCCTGGGCGAATACAGCGCCATGGTCTGCGCCGGCGTCATCGG
TTTCGCCGAGGGCGTGCGCCTGGTGCGCCTGCGTGGCGAGGCCATGCAGGCGGCCGTGCCGGAAGGCCAGGGCGCCATGG
CGGCCGTGCTGGGCCTCGACGATGAAACGGTCGAGACCGCGTGTCGCGATGCGGCACAAGGTGAAGTGGTGTCGGCGGTC
AACTATAATGCGCCGGGTCAGGTCGTGATCGCGGGCAACAAGTCGGCCGTGGAGCGTGCCATTTCGCTGTGTCAGGAGGC
GGGAGCCAAGCGCGCTCTGCCGTTGCCGGTGTCGGTGCCGTCGCACTGCGCGCTGATGCAGCCGGCCGCCGAGCGTCTCG
CCGAGGAAATCGGCGGTCTCGATCTCAAGACGCCGCGCTACACCGTGGTGCAGAACGTCGATGCCCGTGCTCACGACGAC
GTCGACACGCTCAGTCAGCGTCTCGTCGAACAGCTTTATCGCCCGGTGCGCTGGACGGACTGCGTCAACGCCATGCACGA
ACGTGGCGCCCGGGTGTTCATCGAGTGCGGCCCCGGCAAGGTGCTGACCGGTCTCAACAAGCGGATTCAGCGTCAGGCCA
AGGGGCTGGCCGTCAACGACCCCGACTCGCTGGAAAGCGCGCTGGAGCTGGCGCGTAGCGAAGGGGATGAATCTCAGTGA

Upstream 100 bases:

>100_bases
AGCCTTCTACCCACTCGGCCGCGGCAGTCGGCGGTCGAGTGGATAGCGGGTTGGCGAGTGACGCCAGACCCGACGACTCC
CATCCTCAAAGGTGACTGTC

Downstream 100 bases:

>100_bases
TGAATGCGGGAAATCAGATGACAAGCGAACGTAGGGTCGCCCTGGTCACGGGGGCCAGTCGTGGCATCGGGCAAGCGATT
GCACGCGAGCTCGGCCGCCA

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTQSLALVFPGQGSQQVGMLRELAERYSVVRTTFDEASGALGYDLWKVVQEGPESTLNTTACTQPALLTSSVAIWRVWQE
LEGPRPLVMAGHSLGEYSAMVCAGVIGFAEGVRLVRLRGEAMQAAVPEGQGAMAAVLGLDDETVETACRDAAQGEVVSAV
NYNAPGQVVIAGNKSAVERAISLCQEAGAKRALPLPVSVPSHCALMQPAAERLAEEIGGLDLKTPRYTVVQNVDARAHDD
VDTLSQRLVEQLYRPVRWTDCVNAMHERGARVFIECGPGKVLTGLNKRIQRQAKGLAVNDPDSLESALELARSEGDESQ

Sequences:

>Translated_319_residues
MTQSLALVFPGQGSQQVGMLRELAERYSVVRTTFDEASGALGYDLWKVVQEGPESTLNTTACTQPALLTSSVAIWRVWQE
LEGPRPLVMAGHSLGEYSAMVCAGVIGFAEGVRLVRLRGEAMQAAVPEGQGAMAAVLGLDDETVETACRDAAQGEVVSAV
NYNAPGQVVIAGNKSAVERAISLCQEAGAKRALPLPVSVPSHCALMQPAAERLAEEIGGLDLKTPRYTVVQNVDARAHDD
VDTLSQRLVEQLYRPVRWTDCVNAMHERGARVFIECGPGKVLTGLNKRIQRQAKGLAVNDPDSLESALELARSEGDESQ
>Mature_318_residues
TQSLALVFPGQGSQQVGMLRELAERYSVVRTTFDEASGALGYDLWKVVQEGPESTLNTTACTQPALLTSSVAIWRVWQEL
EGPRPLVMAGHSLGEYSAMVCAGVIGFAEGVRLVRLRGEAMQAAVPEGQGAMAAVLGLDDETVETACRDAAQGEVVSAVN
YNAPGQVVIAGNKSAVERAISLCQEAGAKRALPLPVSVPSHCALMQPAAERLAEEIGGLDLKTPRYTVVQNVDARAHDDV
DTLSQRLVEQLYRPVRWTDCVNAMHERGARVFIECGPGKVLTGLNKRIQRQAKGLAVNDPDSLESALELARSEGDESQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=309, Percent_Identity=34.9514563106796, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI27477045, Length=115, Percent_Identity=42.6086956521739, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787334, Length=310, Percent_Identity=59.6774193548387, Blast_Score=353, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI71984332, Length=302, Percent_Identity=27.1523178807947, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=30.1369863013699, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24665753, Length=312, Percent_Identity=34.6153846153846, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34152; Mature: 34021

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSLALVFPGQGSQQVGMLRELAERYSVVRTTFDEASGALGYDLWKVVQEGPESTLNTT
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCH
ACTQPALLTSSVAIWRVWQELEGPRPLVMAGHSLGEYSAMVCAGVIGFAEGVRLVRLRGE
HCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCHHEEEECCH
AMQAAVPEGQGAMAAVLGLDDETVETACRDAAQGEVVSAVNYNAPGQVVIAGNKSAVERA
HHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHH
ISLCQEAGAKRALPLPVSVPSHCALMQPAAERLAEEIGGLDLKTPRYTVVQNVDARAHDD
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
VDTLSQRLVEQLYRPVRWTDCVNAMHERGARVFIECGPGKVLTGLNKRIQRQAKGLAVND
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
PDSLESALELARSEGDESQ
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQSLALVFPGQGSQQVGMLRELAERYSVVRTTFDEASGALGYDLWKVVQEGPESTLNTT
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCH
ACTQPALLTSSVAIWRVWQELEGPRPLVMAGHSLGEYSAMVCAGVIGFAEGVRLVRLRGE
HCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCHHEEEECCH
AMQAAVPEGQGAMAAVLGLDDETVETACRDAAQGEVVSAVNYNAPGQVVIAGNKSAVERA
HHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCHHHHHHH
ISLCQEAGAKRALPLPVSVPSHCALMQPAAERLAEEIGGLDLKTPRYTVVQNVDARAHDD
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
VDTLSQRLVEQLYRPVRWTDCVNAMHERGARVFIECGPGKVLTGLNKRIQRQAKGLAVND
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCC
PDSLESALELARSEGDESQ
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]