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The map label for this gene is ampC [H]

Identifier: 92112328

GI number: 92112328

Start: 215209

End: 216372

Strand: Direct

Name: ampC [H]

Synonym: Csal_0193

Alternate gene names: 92112328

Gene position: 215209-216372 (Clockwise)

Preceding gene: 92112325

Following gene: 92112329

Centisome position: 5.82

GC content: 65.89

Gene sequence:

>1164_bases
ATGAAAGGATGGCTGCTGGGTGTATCGCTGACGTTACTGGGGGCCAGTGGCGTGGCGCAGGCGCAGGCGCAGGACGAGGC
ATCGAACAAGCAGGTGCTCGACCCCATCGTCGCGTCGTTGATGGAAGCGCAGCAGATCCCCGGCATGGCGGTCGCCCTCA
TCGGGCCGAAGGGGACGACGATCGCCGATTACGGCGTCGCCGACCGCAAGACCGGCACGCCGGTCGATGATGACACCCTG
TTCGAGATCGGCTCGCTCAGCAAGACCTTGACCGCGACCCTGGCCTCGTTGGCCGCCGTCGAGGGCGAGCTCGACCTCGA
GGCGCCCGTGAGCCGTTACCTGCCTGAGCTCGAAGGCAGCGCCTTCGACAGGATCGATGGGCTCAATCTTGGTACTCACA
CCGGCGGCGGGCTGCCGCTGTTCGTGCCTGACGAAGTGACCGACCGTGCATCGCTGATGGCCTGGTATCGAGACTGGCAG
CCAAGCGAGCCCATCGGCGAGAGCCGTACCTATTCCAATCTGGGGATCGGCCTGTTGGGTCTGGAGGCGGCGGCGAGCCT
GGGGGGCGAATTCGTGCCGACGATGCGCACCAAGGTGCTGGCGCCGCTCGGCATGCGGGACACCTGGTACGACGTTCCCG
AGGCGCGCATGGCACACTACGCCATGGGCGAGACCAAGGACGGCCAGCCGATTCATGTCTCGTCCGGCGTGCTCGACGAC
GAAGCCTACGGGCTCAAGACCACGGCCGCCGATCTGGCCGGGCTGGTGCGCGCCAACCTGCATCTCGCGGATGTCGACGC
CGAGCTTCAGCAGGCCATCGATGCGACACGCCAGGGCCATTACCGGGTCGGCGACATGACCCAGGCCCTGATCTGGGAGC
AGTATCCGCTGCCCGTGGCGCTCGATACCCTGCGCGCCGGCAACGGTTACGACATGATCCTCGAACCCAACGCGGCCGAG
GCGATCGTGCCACCGCAGGCGCCACGCGATGATGTCTGGATCAACAAGACCGGCTCCACCAACGGCTTTGGCGGCTACAT
CGTGATGCTTCCCGGCGAACAGACGGGGCTGGTGATGCTGGCCAACAAGAACTATCCCAATGACGCGCGCGTCGAGGCGG
CCTACCGCATCCTGTCCGGCCTTGATGTGATCGATGCGCTCTAG

Upstream 100 bases:

>100_bases
ACCATAACATTCTTTTGACCCAAGCATTCCAGCGGCCATGCTTTTGAAGCATGATACCGGCTCGGGAATTTGACTTATCG
ATAGGGGAGCAGGAAGCGCA

Downstream 100 bases:

>100_bases
TGAGTCGGTGCGCGTCTTAGCTCGGCATCAACAGGCTCCACCACGCCACGCCCAGCAGCAGAAGGGCCAGCCCTCGGTTG
AACCATTGCCACTGCCGCCT

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKGWLLGVSLTLLGASGVAQAQAQDEASNKQVLDPIVASLMEAQQIPGMAVALIGPKGTTIADYGVADRKTGTPVDDDTL
FEIGSLSKTLTATLASLAAVEGELDLEAPVSRYLPELEGSAFDRIDGLNLGTHTGGGLPLFVPDEVTDRASLMAWYRDWQ
PSEPIGESRTYSNLGIGLLGLEAAASLGGEFVPTMRTKVLAPLGMRDTWYDVPEARMAHYAMGETKDGQPIHVSSGVLDD
EAYGLKTTAADLAGLVRANLHLADVDAELQQAIDATRQGHYRVGDMTQALIWEQYPLPVALDTLRAGNGYDMILEPNAAE
AIVPPQAPRDDVWINKTGSTNGFGGYIVMLPGEQTGLVMLANKNYPNDARVEAAYRILSGLDVIDAL

Sequences:

>Translated_387_residues
MKGWLLGVSLTLLGASGVAQAQAQDEASNKQVLDPIVASLMEAQQIPGMAVALIGPKGTTIADYGVADRKTGTPVDDDTL
FEIGSLSKTLTATLASLAAVEGELDLEAPVSRYLPELEGSAFDRIDGLNLGTHTGGGLPLFVPDEVTDRASLMAWYRDWQ
PSEPIGESRTYSNLGIGLLGLEAAASLGGEFVPTMRTKVLAPLGMRDTWYDVPEARMAHYAMGETKDGQPIHVSSGVLDD
EAYGLKTTAADLAGLVRANLHLADVDAELQQAIDATRQGHYRVGDMTQALIWEQYPLPVALDTLRAGNGYDMILEPNAAE
AIVPPQAPRDDVWINKTGSTNGFGGYIVMLPGEQTGLVMLANKNYPNDARVEAAYRILSGLDVIDAL
>Mature_387_residues
MKGWLLGVSLTLLGASGVAQAQAQDEASNKQVLDPIVASLMEAQQIPGMAVALIGPKGTTIADYGVADRKTGTPVDDDTL
FEIGSLSKTLTATLASLAAVEGELDLEAPVSRYLPELEGSAFDRIDGLNLGTHTGGGLPLFVPDEVTDRASLMAWYRDWQ
PSEPIGESRTYSNLGIGLLGLEAAASLGGEFVPTMRTKVLAPLGMRDTWYDVPEARMAHYAMGETKDGQPIHVSSGVLDD
EAYGLKTTAADLAGLVRANLHLADVDAELQQAIDATRQGHYRVGDMTQALIWEQYPLPVALDTLRAGNGYDMILEPNAAE
AIVPPQAPRDDVWINKTGSTNGFGGYIVMLPGEQTGLVMLANKNYPNDARVEAAYRILSGLDVIDAL

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=366, Percent_Identity=41.5300546448087, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 41178; Mature: 41178

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGWLLGVSLTLLGASGVAQAQAQDEASNKQVLDPIVASLMEAQQIPGMAVALIGPKGTT
CCCEEEEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCE
IADYGVADRKTGTPVDDDTLFEIGSLSKTLTATLASLAAVEGELDLEAPVSRYLPELEGS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHCCC
AFDRIDGLNLGTHTGGGLPLFVPDEVTDRASLMAWYRDWQPSEPIGESRTYSNLGIGLLG
HHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEH
LEAAASLGGEFVPTMRTKVLAPLGMRDTWYDVPEARMAHYAMGETKDGQPIHVSSGVLDD
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCC
EAYGLKTTAADLAGLVRANLHLADVDAELQQAIDATRQGHYRVGDMTQALIWEQYPLPVA
CCCCCCHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCEE
LDTLRAGNGYDMILEPNAAEAIVPPQAPRDDVWINKTGSTNGFGGYIVMLPGEQTGLVML
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCEEEE
ANKNYPNDARVEAAYRILSGLDVIDAL
ECCCCCCHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MKGWLLGVSLTLLGASGVAQAQAQDEASNKQVLDPIVASLMEAQQIPGMAVALIGPKGTT
CCCEEEEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCE
IADYGVADRKTGTPVDDDTLFEIGSLSKTLTATLASLAAVEGELDLEAPVSRYLPELEGS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHCCC
AFDRIDGLNLGTHTGGGLPLFVPDEVTDRASLMAWYRDWQPSEPIGESRTYSNLGIGLLG
HHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEH
LEAAASLGGEFVPTMRTKVLAPLGMRDTWYDVPEARMAHYAMGETKDGQPIHVSSGVLDD
HHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCC
EAYGLKTTAADLAGLVRANLHLADVDAELQQAIDATRQGHYRVGDMTQALIWEQYPLPVA
CCCCCCHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCEE
LDTLRAGNGYDMILEPNAAEAIVPPQAPRDDVWINKTGSTNGFGGYIVMLPGEQTGLVML
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCEEEE
ANKNYPNDARVEAAYRILSGLDVIDAL
ECCCCCCHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA