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The map label for this gene is mocR [H]

Identifier: 92112292

GI number: 92112292

Start: 178356

End: 179816

Strand: Direct

Name: mocR [H]

Synonym: Csal_0157

Alternate gene names: 92112292

Gene position: 178356-179816 (Clockwise)

Preceding gene: 92112287

Following gene: 92112294

Centisome position: 4.82

GC content: 62.83

Gene sequence:

>1461_bases
ATGCTCGACCATTACTTTCATCTCGATTTCGATGCTCAGCGAGGATTGCAGGAGCAACTGCGCGAAGCGCTGCTCGATGC
CATTCACACCGGCACCATCCCGGCGGATGAGGCATTGCCGTCCTGTCGCCGCTTGTCCCTGCAACTGGGGATCTCGCGCA
ATACCGTGGCGCTGGTGTACGAGGGGCTGGTCGAGGATGGTTATCTGGTCAGTCGTCCACGCAGCGGGTATTACCTGCAT
GACGCCTACCACGACAGCGATGCCCTGGAACTGGCGCAGACCACGCGCCAGCCGGTGCGCGACGCACCATCATGGAGCAA
GCGCTTCACGCATCGCCCCAGTCACTTGCAGGGCGTGTTGCGTCCCAGCAACTGGATGGATTACGAATTTCCCTTCGTAT
ATGGGCAACTGGATACGCGGTTGTTTCCCCTCGAACAATGGCGCGAGACCTCGCGACGCCTGCTGGGCGGGAATCGCGAG
CGTCACTGGCTCAGCGATCGCTACGATCAGGACGACCCTATGCTGATCGAGCAATTGCGCACGCGGGTGCTGCCCAAGCG
CGGCATTCATGCGCAGAGCGATGAGATTTTGGTGACCCTGGGATCGCAGAATGCGCTGTTTCTGATCGCGCAGCTGCTGT
TCGACCGGAAGACGCGAGTCGCCGTCGAGAACCCCGGGTACCGCGAGGCGGTCAATGTCTTCCTGCGCCAGGGCGCCCAG
CTTCACTACCAGCACGTGGACGGCGAGGGCATGCAGCTCGATGCCGAGACTCCACGCTGTGACTATCTCTACGTGACACC
TAGCCATCAGGGACCGACCGGCGCCACCATGAGCCGCGAGCGTCGCGAGCAGTTGATTAAACAGATCCAGCGCTTCGATC
AAATCGTGCTCGAGGACGACTATGACGCAGAGGTGAACTTCGACCGTCATGCGCAACCGGCGCTGAAAGCCAGCCGGGCC
GGCGGGCGGGTGATCTACATGAGTAGCCTGTCCAAGCCGCTCTCACCGGGGCTACGCTTGGGCTATCTCGTGGCCGACGC
CGAGTTGATCGACGAGCTGCGCGCGCTGCGGCGGTTGATGTATCGCCACCCGCCGTCGAGCTTGCAACAACAGCTGGCGC
AGTTTCTCGCCCAGGGACATTACGACCGCTATCTGCGGCAGTTCGCCGACGAGATGCGCCATCGCTGGGAGTGCATGAAC
GATGCCATTGCCAGGCACCTGCCCGGTTGCCGGCGCGTCGGCGGCGATCATGCCAGCGTGTTTTGGCTGGAAGCCCCGGA
GAATGTGGACACCCAGCGCTTGGCCTGGCAGGCCGCGCAGAACGGGGTACTTATCGAGCCGGGCTTTCAGCATTTCTTCG
AGCGCGTGCCGCCGCGCAACTTCATGCGCCTGGGCTTCGGCGCCATCGAGGGAGAGCGCATCGCACCGGGCATCGAGCGC
CTGGCACAAACGCTGGGGTAG

Upstream 100 bases:

>100_bases
AGATGTTTCGATGCCTAACCATGCCGCCAGGCAGCGATCGAGACGTCATGGCGTGTTCCTTGCATCGCTTTCGATGTGAT
GCCTCATCGGGAGATGCACG

Downstream 100 bases:

>100_bases
CGGCGCACCCGCGATGATGCCGGGCGCCAGGCCCGGCGCATGTCATCACGCGTCTGCGGCGGCGATGTCGGCCGCGTTCA
AGGCGGTCAGGCGGCGTACT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MLDHYFHLDFDAQRGLQEQLREALLDAIHTGTIPADEALPSCRRLSLQLGISRNTVALVYEGLVEDGYLVSRPRSGYYLH
DAYHDSDALELAQTTRQPVRDAPSWSKRFTHRPSHLQGVLRPSNWMDYEFPFVYGQLDTRLFPLEQWRETSRRLLGGNRE
RHWLSDRYDQDDPMLIEQLRTRVLPKRGIHAQSDEILVTLGSQNALFLIAQLLFDRKTRVAVENPGYREAVNVFLRQGAQ
LHYQHVDGEGMQLDAETPRCDYLYVTPSHQGPTGATMSRERREQLIKQIQRFDQIVLEDDYDAEVNFDRHAQPALKASRA
GGRVIYMSSLSKPLSPGLRLGYLVADAELIDELRALRRLMYRHPPSSLQQQLAQFLAQGHYDRYLRQFADEMRHRWECMN
DAIARHLPGCRRVGGDHASVFWLEAPENVDTQRLAWQAAQNGVLIEPGFQHFFERVPPRNFMRLGFGAIEGERIAPGIER
LAQTLG

Sequences:

>Translated_486_residues
MLDHYFHLDFDAQRGLQEQLREALLDAIHTGTIPADEALPSCRRLSLQLGISRNTVALVYEGLVEDGYLVSRPRSGYYLH
DAYHDSDALELAQTTRQPVRDAPSWSKRFTHRPSHLQGVLRPSNWMDYEFPFVYGQLDTRLFPLEQWRETSRRLLGGNRE
RHWLSDRYDQDDPMLIEQLRTRVLPKRGIHAQSDEILVTLGSQNALFLIAQLLFDRKTRVAVENPGYREAVNVFLRQGAQ
LHYQHVDGEGMQLDAETPRCDYLYVTPSHQGPTGATMSRERREQLIKQIQRFDQIVLEDDYDAEVNFDRHAQPALKASRA
GGRVIYMSSLSKPLSPGLRLGYLVADAELIDELRALRRLMYRHPPSSLQQQLAQFLAQGHYDRYLRQFADEMRHRWECMN
DAIARHLPGCRRVGGDHASVFWLEAPENVDTQRLAWQAAQNGVLIEPGFQHFFERVPPRNFMRLGFGAIEGERIAPGIER
LAQTLG
>Mature_486_residues
MLDHYFHLDFDAQRGLQEQLREALLDAIHTGTIPADEALPSCRRLSLQLGISRNTVALVYEGLVEDGYLVSRPRSGYYLH
DAYHDSDALELAQTTRQPVRDAPSWSKRFTHRPSHLQGVLRPSNWMDYEFPFVYGQLDTRLFPLEQWRETSRRLLGGNRE
RHWLSDRYDQDDPMLIEQLRTRVLPKRGIHAQSDEILVTLGSQNALFLIAQLLFDRKTRVAVENPGYREAVNVFLRQGAQ
LHYQHVDGEGMQLDAETPRCDYLYVTPSHQGPTGATMSRERREQLIKQIQRFDQIVLEDDYDAEVNFDRHAQPALKASRA
GGRVIYMSSLSKPLSPGLRLGYLVADAELIDELRALRRLMYRHPPSSLQQQLAQFLAQGHYDRYLRQFADEMRHRWECMN
DAIARHLPGCRRVGGDHASVFWLEAPENVDTQRLAWQAAQNGVLIEPGFQHFFERVPPRNFMRLGFGAIEGERIAPGIER
LAQTLG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=316, Percent_Identity=23.1012658227848, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI33469970, Length=316, Percent_Identity=23.1012658227848, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1787710, Length=480, Percent_Identity=26.875, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1790797, Length=466, Percent_Identity=25.5364806866953, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56061; Mature: 56061

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDHYFHLDFDAQRGLQEQLREALLDAIHTGTIPADEALPSCRRLSLQLGISRNTVALVY
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHEECCCCCHHHHHH
EGLVEDGYLVSRPRSGYYLHDAYHDSDALELAQTTRQPVRDAPSWSKRFTHRPSHLQGVL
HHHHCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHCC
RPSNWMDYEFPFVYGQLDTRLFPLEQWRETSRRLLGGNRERHWLSDRYDQDDPMLIEQLR
CCCCCCCEECCEEEECCCCEECCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHH
TRVLPKRGIHAQSDEILVTLGSQNALFLIAQLLFDRKTRVAVENPGYREAVNVFLRQGAQ
HHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCC
LHYQHVDGEGMQLDAETPRCDYLYVTPSHQGPTGATMSRERREQLIKQIQRFDQIVLEDD
EEEEECCCCCCEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCC
YDAEVNFDRHAQPALKASRAGGRVIYMSSLSKPLSPGLRLGYLVADAELIDELRALRRLM
CCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
YRHPPSSLQQQLAQFLAQGHYDRYLRQFADEMRHRWECMNDAIARHLPGCRRVGGDHASV
HCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEE
FWLEAPENVDTQRLAWQAAQNGVLIEPGFQHFFERVPPRNFMRLGFGAIEGERIAPGIER
EEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHH
LAQTLG
HHHHCC
>Mature Secondary Structure
MLDHYFHLDFDAQRGLQEQLREALLDAIHTGTIPADEALPSCRRLSLQLGISRNTVALVY
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHEECCCCCHHHHHH
EGLVEDGYLVSRPRSGYYLHDAYHDSDALELAQTTRQPVRDAPSWSKRFTHRPSHLQGVL
HHHHCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHCC
RPSNWMDYEFPFVYGQLDTRLFPLEQWRETSRRLLGGNRERHWLSDRYDQDDPMLIEQLR
CCCCCCCEECCEEEECCCCEECCHHHHHHHHHHHHCCCCCCCCHHCCCCCCCHHHHHHHH
TRVLPKRGIHAQSDEILVTLGSQNALFLIAQLLFDRKTRVAVENPGYREAVNVFLRQGAQ
HHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCC
LHYQHVDGEGMQLDAETPRCDYLYVTPSHQGPTGATMSRERREQLIKQIQRFDQIVLEDD
EEEEECCCCCCEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCC
YDAEVNFDRHAQPALKASRAGGRVIYMSSLSKPLSPGLRLGYLVADAELIDELRALRRLM
CCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHH
YRHPPSSLQQQLAQFLAQGHYDRYLRQFADEMRHRWECMNDAIARHLPGCRRVGGDHASV
HCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEE
FWLEAPENVDTQRLAWQAAQNGVLIEPGFQHFFERVPPRNFMRLGFGAIEGERIAPGIER
EEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHH
LAQTLG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]