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The map label for this gene is ykkC [H]

Identifier: 92112242

GI number: 92112242

Start: 131233

End: 131607

Strand: Direct

Name: ykkC [H]

Synonym: Csal_0107

Alternate gene names: 92112242

Gene position: 131233-131607 (Clockwise)

Preceding gene: 92112240

Following gene: 92112243

Centisome position: 3.55

GC content: 65.07

Gene sequence:

>375_bases
ATGACGATGCGTTGGTTGATTCTGCCGCTGGCGGCGCTGGCCGAAGTCGGCTGGGCGACGGGCTTGAAACTCGCCAGCAG
TCCTCTCGAGTGGCTGGCGACCGTGATCGTGGCCGCCATGAGCTTGTTGCTGGCGGTACGTGCCGTGCGTTTTCTGCCGG
CCAGTACCGTCTATACGGTCTTCGTGGGCCTGGGGGCGGCAGGCACGGTGGTGGCCGATGCCTGGCTGTTCGGGACACGC
TTTTCCTGGCCCTCGCTGGCTTGCATCGGGCTGATTCTGGTGGGAGTCATCGGCCTGCATCAATTCAGCGGCAAGCCCGC
CGCGCCGGCATCGGTCTCGCGTACCGACGCCTCACGGGAAGGAGTATCGTCATGA

Upstream 100 bases:

>100_bases
CATGGCGCAAACTCTATACTAACGACCGTTAGTTAGTTGCGTGACGCCAACCGGCGTTGCCCCCGGAAGACGCGAGGCGT
CGGCGATCGAGGAGAAAAGG

Downstream 100 bases:

>100_bases
CCTGGCATTGGTTGGCCCTGTTGGGCGCGGGAATTTTCGAAGTACTCGGGGTCGTCGGTTTCGCGCGGGTGAGTCGAGGC
CGGGCGCTGGCCGGCGGCTT

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MTMRWLILPLAALAEVGWATGLKLASSPLEWLATVIVAAMSLLLAVRAVRFLPASTVYTVFVGLGAAGTVVADAWLFGTR
FSWPSLACIGLILVGVIGLHQFSGKPAAPASVSRTDASREGVSS

Sequences:

>Translated_124_residues
MTMRWLILPLAALAEVGWATGLKLASSPLEWLATVIVAAMSLLLAVRAVRFLPASTVYTVFVGLGAAGTVVADAWLFGTR
FSWPSLACIGLILVGVIGLHQFSGKPAAPASVSRTDASREGVSS
>Mature_123_residues
TMRWLILPLAALAEVGWATGLKLASSPLEWLATVIVAAMSLLLAVRAVRFLPASTVYTVFVGLGAAGTVVADAWLFGTRF
SWPSLACIGLILVGVIGLHQFSGKPAAPASVSRTDASREGVSS

Specific function: Part of a multidrug efflux pump. Confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. YkkC/ykkD (TC 2.A.7.1.5) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12897; Mature: 12766

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRWLILPLAALAEVGWATGLKLASSPLEWLATVIVAAMSLLLAVRAVRFLPASTVYTV
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FVGLGAAGTVVADAWLFGTRFSWPSLACIGLILVGVIGLHQFSGKPAAPASVSRTDASRE
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GVSS
CCCC
>Mature Secondary Structure 
TMRWLILPLAALAEVGWATGLKLASSPLEWLATVIVAAMSLLLAVRAVRFLPASTVYTV
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FVGLGAAGTVVADAWLFGTRFSWPSLACIGLILVGVIGLHQFSGKPAAPASVSRTDASRE
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GVSS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA