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The map label for this gene is blh [H]

Identifier: 92109728

GI number: 92109728

Start: 75255

End: 76163

Strand: Reverse

Name: blh [H]

Synonym: Nham_4621

Alternate gene names: 92109728

Gene position: 76163-75255 (Counterclockwise)

Preceding gene: 92109729

Following gene: 92109727

Centisome position: 62.73

GC content: 56.22

Gene sequence:

>909_bases
ATGTCAAACATACATGTCAGCAAAGGCACCCCCATCGTCGCCGGGTTCTTCGAAAAACGCACATCAAGCGTTCAATACGT
AGTGGCCGACCCCGAAACCAAGAAGTGCGCGATTATCGACCCCGTGCTCGATTTCGATCCGAACTCAGGTGCCACCGCGA
CCCATGCCGCGGACGAATTGCTGCATTTCATCAAACATGAAAATTACACACTGCAGTGGGTTCTCGACACGCATCCCCAT
GCGGACCATCTTTCGGCAGCGGGCTATCTGAAAGACAAGACCGGTGTGCCCACAGCGATTGGCGAGAAAGTCGTTGAGGT
CCAAAAGCTATGGAAGGAAATCTACAATTACTCAGACGCGTTCCCCACCGACGGGTCGCAATGGGACAGGCTTTTCCGAG
ATGGCGAGCGATTCAAGATCGGCGATATGGATGTCGAAGTCCTACTAACCCCGGGACATACGCTTGCTTCGATCGCGTAT
CTGGTGGGCGATGCTGCTTTCATTCACGACACCATCTTCATGCCCGATGGGGGTACAGCCAGGGCGGATTTTCCGGGCGG
CAGCGCCCGCGAGCTGTGGAACAGCATCCAGCGCGTCGTGGAGTTGCCGGATAAGACCCGTTTGTTCACGGGGCACGATT
ATTGTCCCGCCGGACGCAAAAAGCCGCTCTGGGAAAGTACGGTCGCTCAGCAACGCGCCGAGAACATCCACCTGACCAAG
GCGCGAACGGAGCAAGAGTTCGTGGCTCTTCGCGAGAAACGCGATCGCGAACTGCCGATGCCGAAACTCATTTTGCATTC
TCTGCAGGTGAATATTCGCGGAGGCCGGCTCCCGGAAACGGAAAAGGACGGCAAGCGCTATCTAAAACTTCCGCTCAATG
CACTCGGAGACGCGCCTTGGAATGCGTGA

Upstream 100 bases:

>100_bases
CACCCTCAATATCGTTTTTGCAAGTCTCGTCATTGCTGTCGGGGTTTACGTGACTGTTCGCGGGCTTACCTCCCTCGTGG
CAACTTAGAGAGCAGTGCAG

Downstream 100 bases:

>100_bases
AAGACGGGATCATGCCAGCTCTCACGATTCGGGCATACTCACCGGCTGCAGCCCGAACCCGCTTGATGCTCGAGACCCAG
TATCGCCCAATCAAACCGAA

Product: beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSNIHVSKGTPIVAGFFEKRTSSVQYVVADPETKKCAIIDPVLDFDPNSGATATHAADELLHFIKHENYTLQWVLDTHPH
ADHLSAAGYLKDKTGVPTAIGEKVVEVQKLWKEIYNYSDAFPTDGSQWDRLFRDGERFKIGDMDVEVLLTPGHTLASIAY
LVGDAAFIHDTIFMPDGGTARADFPGGSARELWNSIQRVVELPDKTRLFTGHDYCPAGRKKPLWESTVAQQRAENIHLTK
ARTEQEFVALREKRDRELPMPKLILHSLQVNIRGGRLPETEKDGKRYLKLPLNALGDAPWNA

Sequences:

>Translated_302_residues
MSNIHVSKGTPIVAGFFEKRTSSVQYVVADPETKKCAIIDPVLDFDPNSGATATHAADELLHFIKHENYTLQWVLDTHPH
ADHLSAAGYLKDKTGVPTAIGEKVVEVQKLWKEIYNYSDAFPTDGSQWDRLFRDGERFKIGDMDVEVLLTPGHTLASIAY
LVGDAAFIHDTIFMPDGGTARADFPGGSARELWNSIQRVVELPDKTRLFTGHDYCPAGRKKPLWESTVAQQRAENIHLTK
ARTEQEFVALREKRDRELPMPKLILHSLQVNIRGGRLPETEKDGKRYLKLPLNALGDAPWNA
>Mature_301_residues
SNIHVSKGTPIVAGFFEKRTSSVQYVVADPETKKCAIIDPVLDFDPNSGATATHAADELLHFIKHENYTLQWVLDTHPHA
DHLSAAGYLKDKTGVPTAIGEKVVEVQKLWKEIYNYSDAFPTDGSQWDRLFRDGERFKIGDMDVEVLLTPGHTLASIAYL
VGDAAFIHDTIFMPDGGTARADFPGGSARELWNSIQRVVELPDKTRLFTGHDYCPAGRKKPLWESTVAQQRAENIHLTKA
RTEQEFVALREKRDRELPMPKLILHSLQVNIRGGRLPETEKDGKRYLKLPLNALGDAPWNA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=273, Percent_Identity=26.3736263736264, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1787158, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=269, Percent_Identity=28.6245353159851, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221330176, Length=263, Percent_Identity=28.8973384030418, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 33852; Mature: 33720

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIHVSKGTPIVAGFFEKRTSSVQYVVADPETKKCAIIDPVLDFDPNSGATATHAADEL
CCCEECCCCCCEEEHHHHHCCCCEEEEEECCCCCCEEEECCHHCCCCCCCCCHHHHHHHH
LHFIKHENYTLQWVLDTHPHADHLSAAGYLKDKTGVPTAIGEKVVEVQKLWKEIYNYSDA
HHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
FPTDGSQWDRLFRDGERFKIGDMDVEVLLTPGHTLASIAYLVGDAAFIHDTIFMPDGGTA
CCCCCHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHHHHHHHCHHHHEEEEECCCCCCE
RADFPGGSARELWNSIQRVVELPDKTRLFTGHDYCPAGRKKPLWESTVAQQRAENIHLTK
ECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEH
ARTEQEFVALREKRDRELPMPKLILHSLQVNIRGGRLPETEKDGKRYLKLPLNALGDAPW
HHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCCEEECCHHHCCCCCC
NA
CC
>Mature Secondary Structure 
SNIHVSKGTPIVAGFFEKRTSSVQYVVADPETKKCAIIDPVLDFDPNSGATATHAADEL
CCEECCCCCCEEEHHHHHCCCCEEEEEECCCCCCEEEECCHHCCCCCCCCCHHHHHHHH
LHFIKHENYTLQWVLDTHPHADHLSAAGYLKDKTGVPTAIGEKVVEVQKLWKEIYNYSDA
HHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
FPTDGSQWDRLFRDGERFKIGDMDVEVLLTPGHTLASIAYLVGDAAFIHDTIFMPDGGTA
CCCCCHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHHHHHHHCHHHHEEEEECCCCCCE
RADFPGGSARELWNSIQRVVELPDKTRLFTGHDYCPAGRKKPLWESTVAQQRAENIHLTK
ECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEH
ARTEQEFVALREKRDRELPMPKLILHSLQVNIRGGRLPETEKDGKRYLKLPLNALGDAPW
HHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCCEEECCHHHCCCCCC
NA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]