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The map label for this gene is ytfL [C]

Identifier: 92109710

GI number: 92109710

Start: 46677

End: 48005

Strand: Reverse

Name: ytfL [C]

Synonym: Nham_4594

Alternate gene names: 92109710

Gene position: 48005-46677 (Counterclockwise)

Preceding gene: 92109717

Following gene: 92109709

Centisome position: 39.54

GC content: 57.64

Gene sequence:

>1329_bases
ATGCCTGACGGCGATGGCAGTAGCCTCAATCTTATCGGTATTGTACTGATCTTTGTTCTTGTTGCGGCGAACGGATTTTT
CGTCGCGGCCGAGTTCTCCTTGGTGGCGGTTCGTCCGAGCAGGGTTGCCGAATTGGTCGCCGGCGGCAGCAGAAGGGCCC
TTGTCCTTCAACGAGCCATCCAGCACCTTGATGTCAATCTAGCCGCCACGCAATTGGGAATCACGATTTCGTCACTCGCC
TTGGGTTGGATTGGCGAACCTGCCTTGGCGGGATTGATCCAGCCGCTGTGGAAGGCATTCCCGGATTCCCTTGCGACCGC
CGGCGCGCATGCCGTAGCGGTTGTCGTTTCCTTCAGCATCATCACTACGTTGCATATCGTATTGGGCGAATTGGCGCCAA
AGAGCTTGGCATTGCAGCGAAGCGAAAGTACCGCGCTTGTGATTGTGCGCCCGTTGGGGCTGTTCCTGCTCATCTTGCGT
CCAGCAATCGTTATACTGAATGGCCTCGGCAACCTGATTCTCCGGCTTTGCGGCCTGCGGCCCGGAACGGGCGAATCCTC
GCTGCATTCACCGGAGGAGTTGAAGCTGCTGGTGCAAGCCAGTCAGGACGCAGGCATCCTGCAAGACGCACAGGAAGAGG
TGGTGCTTCGCGTTCTCAACATCGGGGAGCGGCAGGTCGGCGACATCATGACCGCGCGGCCTGAAATCGACTGGGTCAAT
GCTGATTCGGATCGCGCCGACATGCTTGATACGATCAGAAACTGTCCTCACGAGCAGTTGCTCGTTGGGCGGGGCAGCAT
CGACGAGCCTCTTGGCATGCTCCTCAAAAAGGATTTGCTTAATCGCGTGCTGGGTGGAGAGGGCCTCGATCCATTGGAGG
TGATCCGGGAGCCGTTGCTCGTTCTTGAATCCATGTCGGTATTCCGGATGCTGGACATGTTCAAGCAAGCTCCCGTGCGG
CTTGCGATCGTCGTCGATGAATATGGAATCCTTCAGGGCATTGTCACGCAGACCGATCTCCTTGAAGCGATTGCCGGCGA
TTTGCCGAACAGCGAGGATGGATCGGCGGATATCATCGAACGCGAGGATGGATCGTTGCTCCTTGACGGGATGACGCCGG
CACACGACGTATTCGACCGCCTTGCATTCCGGAAGCGCCCAGAGAACGGCGATTATCACACGGTTGCCGGATTCGCGCTG
TCCCAACTCGGTCATCTGCCCGGGATCGGCGAGTCTTTCGTATATGAAGATTGGTGTTTCGAGATCGTCGATCTGGACGG
GCGACGCATCGGCAAGATTCTCGCGACAAGGATGACGCTTGTGCCCTGA

Upstream 100 bases:

>100_bases
GATCGCCGGGAGAAGCTATGGGAAGCGGCAAGGTTGAGGCTGGGTATGACGGATCGTATAGCGAGTATACGAAGCTTTGA
ATCAACCCAAGAGGAGAGTT

Downstream 100 bases:

>100_bases
ACGACTTCCTACCGCAAATGACTCCGTCGTTGCCGGGGAGCGACGATCTGCTAAGCGTCGTTGGCAGCGCTTCCAGCGTG
CAAAGGCGTATGGCTGGTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPDGDGSSLNLIGIVLIFVLVAANGFFVAAEFSLVAVRPSRVAELVAGGSRRALVLQRAIQHLDVNLAATQLGITISSLA
LGWIGEPALAGLIQPLWKAFPDSLATAGAHAVAVVVSFSIITTLHIVLGELAPKSLALQRSESTALVIVRPLGLFLLILR
PAIVILNGLGNLILRLCGLRPGTGESSLHSPEELKLLVQASQDAGILQDAQEEVVLRVLNIGERQVGDIMTARPEIDWVN
ADSDRADMLDTIRNCPHEQLLVGRGSIDEPLGMLLKKDLLNRVLGGEGLDPLEVIREPLLVLESMSVFRMLDMFKQAPVR
LAIVVDEYGILQGIVTQTDLLEAIAGDLPNSEDGSADIIEREDGSLLLDGMTPAHDVFDRLAFRKRPENGDYHTVAGFAL
SQLGHLPGIGESFVYEDWCFEIVDLDGRRIGKILATRMTLVP

Sequences:

>Translated_442_residues
MPDGDGSSLNLIGIVLIFVLVAANGFFVAAEFSLVAVRPSRVAELVAGGSRRALVLQRAIQHLDVNLAATQLGITISSLA
LGWIGEPALAGLIQPLWKAFPDSLATAGAHAVAVVVSFSIITTLHIVLGELAPKSLALQRSESTALVIVRPLGLFLLILR
PAIVILNGLGNLILRLCGLRPGTGESSLHSPEELKLLVQASQDAGILQDAQEEVVLRVLNIGERQVGDIMTARPEIDWVN
ADSDRADMLDTIRNCPHEQLLVGRGSIDEPLGMLLKKDLLNRVLGGEGLDPLEVIREPLLVLESMSVFRMLDMFKQAPVR
LAIVVDEYGILQGIVTQTDLLEAIAGDLPNSEDGSADIIEREDGSLLLDGMTPAHDVFDRLAFRKRPENGDYHTVAGFAL
SQLGHLPGIGESFVYEDWCFEIVDLDGRRIGKILATRMTLVP
>Mature_441_residues
PDGDGSSLNLIGIVLIFVLVAANGFFVAAEFSLVAVRPSRVAELVAGGSRRALVLQRAIQHLDVNLAATQLGITISSLAL
GWIGEPALAGLIQPLWKAFPDSLATAGAHAVAVVVSFSIITTLHIVLGELAPKSLALQRSESTALVIVRPLGLFLLILRP
AIVILNGLGNLILRLCGLRPGTGESSLHSPEELKLLVQASQDAGILQDAQEEVVLRVLNIGERQVGDIMTARPEIDWVNA
DSDRADMLDTIRNCPHEQLLVGRGSIDEPLGMLLKKDLLNRVLGGEGLDPLEVIREPLLVLESMSVFRMLDMFKQAPVRL
AIVVDEYGILQGIVTQTDLLEAIAGDLPNSEDGSADIIEREDGSLLLDGMTPAHDVFDRLAFRKRPENGDYHTVAGFALS
QLGHLPGIGESFVYEDWCFEIVDLDGRRIGKILATRMTLVP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=362, Percent_Identity=32.3204419889503, Blast_Score=202, Evalue=4e-52,
Organism=Escherichia coli, GI1790664, Length=430, Percent_Identity=28.6046511627907, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87082033, Length=235, Percent_Identity=31.063829787234, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=23.5011990407674, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788119, Length=207, Percent_Identity=31.4009661835749, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786879, Length=273, Percent_Identity=27.4725274725275, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47625; Mature: 47494

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGDGSSLNLIGIVLIFVLVAANGFFVAAEFSLVAVRPSRVAELVAGGSRRALVLQRAI
CCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEEECHHHHHHHHHCCCCHHHHHHHHH
QHLDVNLAATQLGITISSLALGWIGEPALAGLIQPLWKAFPDSLATAGAHAVAVVVSFSI
HHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHH
ITTLHIVLGELAPKSLALQRSESTALVIVRPLGLFLLILRPAIVILNGLGNLILRLCGLR
HHHHHHHHHHCCCHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGTGESSLHSPEELKLLVQASQDAGILQDAQEEVVLRVLNIGERQVGDIMTARPEIDWVN
CCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEC
ADSDRADMLDTIRNCPHEQLLVGRGSIDEPLGMLLKKDLLNRVLGGEGLDPLEVIREPLL
CCCCHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VLESMSVFRMLDMFKQAPVRLAIVVDEYGILQGIVTQTDLLEAIAGDLPNSEDGSADIIE
HHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
REDGSLLLDGMTPAHDVFDRLAFRKRPENGDYHTVAGFALSQLGHLPGIGESFVYEDWCF
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
EIVDLDGRRIGKILATRMTLVP
HHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDGDGSSLNLIGIVLIFVLVAANGFFVAAEFSLVAVRPSRVAELVAGGSRRALVLQRAI
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEEECHHHHHHHHHCCCCHHHHHHHHH
QHLDVNLAATQLGITISSLALGWIGEPALAGLIQPLWKAFPDSLATAGAHAVAVVVSFSI
HHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHH
ITTLHIVLGELAPKSLALQRSESTALVIVRPLGLFLLILRPAIVILNGLGNLILRLCGLR
HHHHHHHHHHCCCHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGTGESSLHSPEELKLLVQASQDAGILQDAQEEVVLRVLNIGERQVGDIMTARPEIDWVN
CCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEC
ADSDRADMLDTIRNCPHEQLLVGRGSIDEPLGMLLKKDLLNRVLGGEGLDPLEVIREPLL
CCCCHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VLESMSVFRMLDMFKQAPVRLAIVVDEYGILQGIVTQTDLLEAIAGDLPNSEDGSADIIE
HHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
REDGSLLLDGMTPAHDVFDRLAFRKRPENGDYHTVAGFALSQLGHLPGIGESFVYEDWCF
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHH
EIVDLDGRRIGKILATRMTLVP
HHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]