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The map label for this gene is cph1 [H]

Identifier: 91789154

GI number: 91789154

Start: 3490039

End: 3492183

Strand: Direct

Name: cph1 [H]

Synonym: Bpro_3294

Alternate gene names: 91789154

Gene position: 3490039-3492183 (Clockwise)

Preceding gene: 91789153

Following gene: 91789155

Centisome position: 67.11

GC content: 67.13

Gene sequence:

>2145_bases
ATGGCGAACAACAGCCCAGCCCCGGCACCTGCGCCGACCCGCGCCGCAGTCGCTGGAATTCGGGCGCTGTTTTGGCCTTT
GTCCCTCATGATGTCTGTCGTCGTGGCGCTGACGATATGGGCCATTGTTGAAAGCCAGGACCAATACCGTGAACGAGAGG
CTGCCCGCATCGAAGCCATGGCCGACCTGCGTGCCGGCCAGGTTGCCACCTGGCTGCGGGAGAATCTCGGCCGGGTAGAG
TTCGCCGGCCGCAGCCCGATGGGTGAAACCTACCTGCTCTGGCGCAATGTGGGCGACACCGCTGCCCATGAACGGCTGCT
GGACCGCCTGTCCAGCTTTCACAAGGCCAGCGGAGGCCACAGCGTGCTGGTGATGGACGACCAGGGCCAAGTCGTCGCGG
GCACGACCAATGCAGAACAGCAGGCGCCGCCCCTCTTGCGCGATGCGGCGCGGCGAGCCATCGACAGCAACAAGCCGCAG
TTCACCAACCTCTACGGGCACGATGGCGCGCCACCGGCACCGCGGATTGACGTGGTGGCGCCGTTCACACTCACCGGCAA
GCCGGCGCGCGCGGTGCTGGTGGTGAGACTCGACCCCCACGTCTTTCTGTTTCCGACGCTGCGCGAATGGCCGCTGCCCA
GCCGCAGTGCGGCCTCCGTGCTGGTACGGCGCGAAGGCGATTTTCTGGTCGAGCCCAATTCAGGGACCCGCCTGCCGCTG
TCCTCGCCCGACCTGCTGGCGGCCAAGGTTATACGCGGCGATGCGCCGCTCGGTCGGGCCGTCGACGCACTGGATTTCCA
CGGCCAGCCGGTGCTCGGCGTGGTGCGCCCGATAGCGGGAACAGATTGGTTTCTGATGGCCAGGATGGACAGCGGCGAGG
CCTATGCCGACGCGTGGCGCAATGCACTCTGGATCGCCGCTGCGGGCATGCTGGCCCTGCTTGCGACTGGGGCTGGCGCC
TACTGGTTCCGCGAGCGCCAGGCCCTGCAGTTTGCGCGCATCGAACGCGCCCACCAGGAAGAGAAATTGCGCGCGCTGCA
ACTGCTGGATGCCATCGCGCAGGGCTCGACCGACTCGATTTTCGCCAAGGACAGGACCGGCCGCTATCTGCTGTGCAACA
AGGCGGGTTGCGAGGCCTTGGGCAAAACAATGGAAGAAGTCATAGGCAGCGACGACCGCGCGCTGTTTCCGCCCGCTGAA
GCCGCCCGCCTGGCCGCCAGCGACGCGCAAGCCTTGACGCAGGGCCGCACCATCAGCTACGAGGTGGAACTCACCACCCC
GCGCGGGCTGTCCACCTTCTTCACGACCAAGGGCCCCTTGCGCAACACAGCGGGCGAGGTGACTGGCGTCTTCGGCATCT
CGCGCGACATCACCGAGCGCAGCCGCATCAGCGCTGAACTGGACCTCCACCGCCATCACCTGGAAGAACTGGTCAAGGAA
CGCACGGCAGCGCTGGAGCGCACCGTCAGCGACCTGGAAGCCTTCAGCGCCAGCGTGTCGCACGACCTGCGCAGCCCGCT
ACACACCATCGGCGGCTTTGCCACGCTACTGGAACGCTCGGAAGCGTCCGCGCTGTCCGACAGCGGGCGTCACAAATTGG
CCCGCATCATCGCCGGGGCGGCGACGATGGACCGCATGATCCAGGACATCCTGGCGTGCTCACGCGCCGAGCGCGTGGAG
ATGACCTTCCGGCCGGTCGATCTCAACGAGCTGGTGGGCAAGTTGGTGCGCGAGCTGGCGCCGGCCTGTCCGAACAGCCA
CATCAGCGCCGGCCCGCTGCCCGTGGTGCAGGCCGACCCGACGCTGATGGGCCAGGTCTTCAACAACCTGATCGGCAACG
CGCTGAAGTTTTCCGCCGGGCAAAGCCCGCCGCGCGTGGAGATCGGCACGCAGGAAGGGCCGGACGGCACCGAAATTTTC
GTGCGCGACAACGGCGTGGGGTTCGATGCGGCCCAGTCGGACAAGCTGTTCGCGCCTTTCCAGCGCCTGCACCGCGCTGA
AGATTTTGCCGGCACCGGCGTGGGCCTGTCCATCGTCAAGCGGCTGATCGAGCGCCATGGCGGGCGCATCCGTGCCGAGT
CGACGCCGGGCGAACGTACGACCTTCGCGTTCACCCTGGGGCCGGCCGCGCTGGCGCATCCATAG

Upstream 100 bases:

>100_bases
AATGACCTCGGAACCACGTAGCGCTGCTGCGGTTCTATGCCAGTAAGGTGCCCACCCGGCAGGCAGTCGATCTGCCCGGG
CGGGTTCGGAGGACCTGAAT

Downstream 100 bases:

>100_bases
GATAATACGGGGCATTCCACGCAAAGCCCGGCTCGTTCCGGCCACCTTCGCACCTTCTTCCACCAGCCCCGTCGCGGCAG
TCCAAAAAGCGGCGTGCGCC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MANNSPAPAPAPTRAAVAGIRALFWPLSLMMSVVVALTIWAIVESQDQYREREAARIEAMADLRAGQVATWLRENLGRVE
FAGRSPMGETYLLWRNVGDTAAHERLLDRLSSFHKASGGHSVLVMDDQGQVVAGTTNAEQQAPPLLRDAARRAIDSNKPQ
FTNLYGHDGAPPAPRIDVVAPFTLTGKPARAVLVVRLDPHVFLFPTLREWPLPSRSAASVLVRREGDFLVEPNSGTRLPL
SSPDLLAAKVIRGDAPLGRAVDALDFHGQPVLGVVRPIAGTDWFLMARMDSGEAYADAWRNALWIAAAGMLALLATGAGA
YWFRERQALQFARIERAHQEEKLRALQLLDAIAQGSTDSIFAKDRTGRYLLCNKAGCEALGKTMEEVIGSDDRALFPPAE
AARLAASDAQALTQGRTISYEVELTTPRGLSTFFTTKGPLRNTAGEVTGVFGISRDITERSRISAELDLHRHHLEELVKE
RTAALERTVSDLEAFSASVSHDLRSPLHTIGGFATLLERSEASALSDSGRHKLARIIAGAATMDRMIQDILACSRAERVE
MTFRPVDLNELVGKLVRELAPACPNSHISAGPLPVVQADPTLMGQVFNNLIGNALKFSAGQSPPRVEIGTQEGPDGTEIF
VRDNGVGFDAAQSDKLFAPFQRLHRAEDFAGTGVGLSIVKRLIERHGGRIRAESTPGERTTFAFTLGPAALAHP

Sequences:

>Translated_714_residues
MANNSPAPAPAPTRAAVAGIRALFWPLSLMMSVVVALTIWAIVESQDQYREREAARIEAMADLRAGQVATWLRENLGRVE
FAGRSPMGETYLLWRNVGDTAAHERLLDRLSSFHKASGGHSVLVMDDQGQVVAGTTNAEQQAPPLLRDAARRAIDSNKPQ
FTNLYGHDGAPPAPRIDVVAPFTLTGKPARAVLVVRLDPHVFLFPTLREWPLPSRSAASVLVRREGDFLVEPNSGTRLPL
SSPDLLAAKVIRGDAPLGRAVDALDFHGQPVLGVVRPIAGTDWFLMARMDSGEAYADAWRNALWIAAAGMLALLATGAGA
YWFRERQALQFARIERAHQEEKLRALQLLDAIAQGSTDSIFAKDRTGRYLLCNKAGCEALGKTMEEVIGSDDRALFPPAE
AARLAASDAQALTQGRTISYEVELTTPRGLSTFFTTKGPLRNTAGEVTGVFGISRDITERSRISAELDLHRHHLEELVKE
RTAALERTVSDLEAFSASVSHDLRSPLHTIGGFATLLERSEASALSDSGRHKLARIIAGAATMDRMIQDILACSRAERVE
MTFRPVDLNELVGKLVRELAPACPNSHISAGPLPVVQADPTLMGQVFNNLIGNALKFSAGQSPPRVEIGTQEGPDGTEIF
VRDNGVGFDAAQSDKLFAPFQRLHRAEDFAGTGVGLSIVKRLIERHGGRIRAESTPGERTTFAFTLGPAALAHP
>Mature_713_residues
ANNSPAPAPAPTRAAVAGIRALFWPLSLMMSVVVALTIWAIVESQDQYREREAARIEAMADLRAGQVATWLRENLGRVEF
AGRSPMGETYLLWRNVGDTAAHERLLDRLSSFHKASGGHSVLVMDDQGQVVAGTTNAEQQAPPLLRDAARRAIDSNKPQF
TNLYGHDGAPPAPRIDVVAPFTLTGKPARAVLVVRLDPHVFLFPTLREWPLPSRSAASVLVRREGDFLVEPNSGTRLPLS
SPDLLAAKVIRGDAPLGRAVDALDFHGQPVLGVVRPIAGTDWFLMARMDSGEAYADAWRNALWIAAAGMLALLATGAGAY
WFRERQALQFARIERAHQEEKLRALQLLDAIAQGSTDSIFAKDRTGRYLLCNKAGCEALGKTMEEVIGSDDRALFPPAEA
ARLAASDAQALTQGRTISYEVELTTPRGLSTFFTTKGPLRNTAGEVTGVFGISRDITERSRISAELDLHRHHLEELVKER
TAALERTVSDLEAFSASVSHDLRSPLHTIGGFATLLERSEASALSDSGRHKLARIIAGAATMDRMIQDILACSRAERVEM
TFRPVDLNELVGKLVRELAPACPNSHISAGPLPVVQADPTLMGQVFNNLIGNALKFSAGQSPPRVEIGTQEGPDGTEIFV
RDNGVGFDAAQSDKLFAPFQRLHRAEDFAGTGVGLSIVKRLIERHGGRIRAESTPGERTTFAFTLGPAALAHP

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG4251

COG function: function code T; Bacteriophytochrome (light-regulated signal transduction histidine kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=403, Percent_Identity=28.5359801488834, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788549, Length=374, Percent_Identity=25.9358288770053, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI145693157, Length=337, Percent_Identity=27.893175074184, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=30.672268907563, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=28.1938325991189, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=29.6803652968037, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788713, Length=266, Percent_Identity=28.1954887218045, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=28.6885245901639, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=281, Percent_Identity=29.1814946619217, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=26.4822134387352, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=26.9767441860465, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=26.3636363636364, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77317; Mature: 77186

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANNSPAPAPAPTRAAVAGIRALFWPLSLMMSVVVALTIWAIVESQDQYREREAARIEAM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ADLRAGQVATWLRENLGRVEFAGRSPMGETYLLWRNVGDTAAHERLLDRLSSFHKASGGH
HHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
SVLVMDDQGQVVAGTTNAEQQAPPLLRDAARRAIDSNKPQFTNLYGHDGAPPAPRIDVVA
EEEEECCCCCEEEECCCCHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEE
PFTLTGKPARAVLVVRLDPHVFLFPTLREWPLPSRSAASVLVRREGDFLVEPNSGTRLPL
CEEECCCCCEEEEEEEECCCEEEECCHHCCCCCCCHHHHEEEEECCCEEEECCCCCCCCC
SSPDLLAAKVIRGDAPLGRAVDALDFHGQPVLGVVRPIAGTDWFLMARMDSGEAYADAWR
CCCCHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
NALWIAAAGMLALLATGAGAYWFRERQALQFARIERAHQEEKLRALQLLDAIAQGSTDSI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FAKDRTGRYLLCNKAGCEALGKTMEEVIGSDDRALFPPAEAARLAASDAQALTQGRTISY
EEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCEEEE
EVELTTPRGLSTFFTTKGPLRNTAGEVTGVFGISRDITERSRISAELDLHRHHLEELVKE
EEEECCCCCCCHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAALERTVSDLEAFSASVSHDLRSPLHTIGGFATLLERSEASALSDSGRHKLARIIAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ATMDRMIQDILACSRAERVEMTFRPVDLNELVGKLVRELAPACPNSHISAGPLPVVQADP
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCH
TLMGQVFNNLIGNALKFSAGQSPPRVEIGTQEGPDGTEIFVRDNGVGFDAAQSDKLFAPF
HHHHHHHHHHHCCHHEECCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHH
QRLHRAEDFAGTGVGLSIVKRLIERHGGRIRAESTPGERTTFAFTLGPAALAHP
HHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCHHHCCC
>Mature Secondary Structure 
ANNSPAPAPAPTRAAVAGIRALFWPLSLMMSVVVALTIWAIVESQDQYREREAARIEAM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ADLRAGQVATWLRENLGRVEFAGRSPMGETYLLWRNVGDTAAHERLLDRLSSFHKASGGH
HHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
SVLVMDDQGQVVAGTTNAEQQAPPLLRDAARRAIDSNKPQFTNLYGHDGAPPAPRIDVVA
EEEEECCCCCEEEECCCCHHHCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEE
PFTLTGKPARAVLVVRLDPHVFLFPTLREWPLPSRSAASVLVRREGDFLVEPNSGTRLPL
CEEECCCCCEEEEEEEECCCEEEECCHHCCCCCCCHHHHEEEEECCCEEEECCCCCCCCC
SSPDLLAAKVIRGDAPLGRAVDALDFHGQPVLGVVRPIAGTDWFLMARMDSGEAYADAWR
CCCCHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
NALWIAAAGMLALLATGAGAYWFRERQALQFARIERAHQEEKLRALQLLDAIAQGSTDSI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FAKDRTGRYLLCNKAGCEALGKTMEEVIGSDDRALFPPAEAARLAASDAQALTQGRTISY
EEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCEEEE
EVELTTPRGLSTFFTTKGPLRNTAGEVTGVFGISRDITERSRISAELDLHRHHLEELVKE
EEEECCCCCCCHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAALERTVSDLEAFSASVSHDLRSPLHTIGGFATLLERSEASALSDSGRHKLARIIAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ATMDRMIQDILACSRAERVEMTFRPVDLNELVGKLVRELAPACPNSHISAGPLPVVQADP
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCH
TLMGQVFNNLIGNALKFSAGQSPPRVEIGTQEGPDGTEIFVRDNGVGFDAAQSDKLFAPF
HHHHHHHHHHHCCHHEECCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHH
QRLHRAEDFAGTGVGLSIVKRLIERHGGRIRAESTPGERTTFAFTLGPAALAHP
HHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]