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The map label for this gene is ppiD [H]

Identifier: 91788924

GI number: 91788924

Start: 3229184

End: 3231115

Strand: Reverse

Name: ppiD [H]

Synonym: Bpro_3064

Alternate gene names: 91788924

Gene position: 3231115-3229184 (Counterclockwise)

Preceding gene: 91788925

Following gene: 91788921

Centisome position: 62.13

GC content: 58.8

Gene sequence:

>1932_bases
ATGTTTGATTTCATTCGCAAGCACACCAAAGTCACCATGGCCTTGCTGTTTTTGCTGATTGTTCCGTCGTTTATTTTGTT
TGGCCTCGATGGCTACAACCGATCGAGGGAACAAGGCGTGGCGGTTGCCAGGGTGGATGGAAAAGACATCATCCAGTCCG
AGTGGGACCGCGCGCATCAGCTGGAAGTTGACAGATTGCGGGCTTCCATGCCTTCGCTGGATGCCAAGCTGCTGGATTCA
CCGCAGGCCCGTTATGCCACGCTGGAGCGCCTGGTGCGCGATCGCGTGATCGCCGCCGCGGCCGACAAATTCAAGCTTGT
CATCAGTGACCAGCGTCTGGCCCGCGAACTGCAGCAGAGTTCCGAGATTGCGTCACTGCGCCGCTCTGATGGCAACCTCG
ACATGGAGCGCTATCGCCAGGTGCTGGGCAGCCAGGGCATGAGCCCCGAGATGTTCGAGGCCAATGTGCGGGCCGATCTG
TCGAATCGCCAGGTGCTGACGGGCATTGGCGCCAGCGGTTTTTCTTCCAGCTCCGCGGCCGACCTGGCGCTCAACGCCTA
TTTCGAAAAACGAGAAATTCAGCTTGCCCGTTTCAATGCGGCTGATTTCGCGGCGAAGCTCAGCCCTACAGATGCCGATC
TCGATCAGTTCTACAAGGCGAACGAAAAACTCTTTCAGGCGCCGGAGCAGGCGAGTATCGAGTACGTGATGCTGGACGTG
GAGACGGTCAGGAAAAGTATCACGATCAATGAGGCGGACCTGAAGACCTATTACGAGCAGAACCTCCAGAGGCTCAGTGG
CGCCGAAGAGCGGCGAGCCAGCCATATCCTCATTACCTCGCCCAAGACAGCGTCTGCCGAGGAACGCCAGAAGGCCAAGG
CCAAGGCCGAGGAGCTGCTGGCTGCCGTCAAAAAATCTCCCGATACCTTTGCCGACGTGGCGCGCAAGAATTCGCAGGAC
CCGGGTTCCGCACCCAGTGGTGGCGATCTCGATTTCTTTGCCCGGGGCGCCATGGTCAAGCCGTTTGAAGATGCCGTGTT
CTCGATGAAAAAAGGGGACATCAGTGCTGTGGTGGAGTCCGAGTTTGGCTACCACATCATCAGGCTCACCGACATCAAGG
CACCCAAGCAGCGCAGTTTCGAAGAGATGAAGCCCGAGCTGGAAGCCGACTTGAAGAAGCAGCAAGCCCAGAAGAAGTTT
TCTGAAGCCGCAGAAGCCTTCACCAATGGCGTGTATGAGCAGGCGGGCAGCCTCAAGCCGGTTGCGGAGCGCCTCAAGCT
GGATATCAAGACGGCCAGCAACGTGACGCGTCAACCGTCAGCAGGTACTACGGGTGTGCTCGCCAATCCGAAATTCCTCA
ATGCACTGTTTGGGCCCGATGCGGTCGAGAAAAAGCGCAATACCGAAGCCATTGAAGTGGCACCCAGCCAACTGGTTTCG
GGCCGCATCCTCCAGTACACCCCGGCGCGTACCCAGCCTTTTGCAGAGGTGAAAGACATCGTGCGCCAGCGCTGGCTGGC
TCAACGTAGTGCAGAAGAAGCTCGCAAGGAAGGTCTCGCCAAACTGGTGGCCTGGAAGGCCGCTCCGGCTTCGGCCGTGC
TGGCAGCGCCGGTGCTGGTGTCGCGTGAGCAAACCCAGAACCTGCCGGTTCAGGTGATTGATGCTGCCCTGCGCGTTGAC
GCCAGTGCACTGCCGGTGTTTGCGGGCGTTGACCTGGGTGCCCAGGGCTATGCCATCGTGAAGGTCGCTAAAGTGATGCC
CCGCGATGCGCGACCTGACGCCGCAGCCAAACAGGAGCGCAACCAGTACGCCCAATGGTGGACGTCTGCCGAGAATCTGG
CTTATTACAACGGCCTGAAGGAACGTTTCAAGGCGGAAATCCTGGTCGCAAAGCCCGCATCCGTGAATGCAGACGAGGTC
GTGACGCAATAA

Upstream 100 bases:

>100_bases
GCACCCACCACCCATTGAAAAAGGCGAACGAGGTTCGCCTTTTTTGTTGTGGGCCCCCTGGTTTTATCGGTAAAGCAGTC
AGTCGTACAGGAAATTCGAG

Downstream 100 bases:

>100_bases
ACGCCCGCTGCTTTGCCGCTATAATGTGAAGTTCTGGTGGCTGTAGCTCAGTTGGTAGAGTCCAGGATTGTGATTCCTGT
TGTCGTGGGTTCGAGCCCCA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MFDFIRKHTKVTMALLFLLIVPSFILFGLDGYNRSREQGVAVARVDGKDIIQSEWDRAHQLEVDRLRASMPSLDAKLLDS
PQARYATLERLVRDRVIAAAADKFKLVISDQRLARELQQSSEIASLRRSDGNLDMERYRQVLGSQGMSPEMFEANVRADL
SNRQVLTGIGASGFSSSSAADLALNAYFEKREIQLARFNAADFAAKLSPTDADLDQFYKANEKLFQAPEQASIEYVMLDV
ETVRKSITINEADLKTYYEQNLQRLSGAEERRASHILITSPKTASAEERQKAKAKAEELLAAVKKSPDTFADVARKNSQD
PGSAPSGGDLDFFARGAMVKPFEDAVFSMKKGDISAVVESEFGYHIIRLTDIKAPKQRSFEEMKPELEADLKKQQAQKKF
SEAAEAFTNGVYEQAGSLKPVAERLKLDIKTASNVTRQPSAGTTGVLANPKFLNALFGPDAVEKKRNTEAIEVAPSQLVS
GRILQYTPARTQPFAEVKDIVRQRWLAQRSAEEARKEGLAKLVAWKAAPASAVLAAPVLVSREQTQNLPVQVIDAALRVD
ASALPVFAGVDLGAQGYAIVKVAKVMPRDARPDAAAKQERNQYAQWWTSAENLAYYNGLKERFKAEILVAKPASVNADEV
VTQ

Sequences:

>Translated_643_residues
MFDFIRKHTKVTMALLFLLIVPSFILFGLDGYNRSREQGVAVARVDGKDIIQSEWDRAHQLEVDRLRASMPSLDAKLLDS
PQARYATLERLVRDRVIAAAADKFKLVISDQRLARELQQSSEIASLRRSDGNLDMERYRQVLGSQGMSPEMFEANVRADL
SNRQVLTGIGASGFSSSSAADLALNAYFEKREIQLARFNAADFAAKLSPTDADLDQFYKANEKLFQAPEQASIEYVMLDV
ETVRKSITINEADLKTYYEQNLQRLSGAEERRASHILITSPKTASAEERQKAKAKAEELLAAVKKSPDTFADVARKNSQD
PGSAPSGGDLDFFARGAMVKPFEDAVFSMKKGDISAVVESEFGYHIIRLTDIKAPKQRSFEEMKPELEADLKKQQAQKKF
SEAAEAFTNGVYEQAGSLKPVAERLKLDIKTASNVTRQPSAGTTGVLANPKFLNALFGPDAVEKKRNTEAIEVAPSQLVS
GRILQYTPARTQPFAEVKDIVRQRWLAQRSAEEARKEGLAKLVAWKAAPASAVLAAPVLVSREQTQNLPVQVIDAALRVD
ASALPVFAGVDLGAQGYAIVKVAKVMPRDARPDAAAKQERNQYAQWWTSAENLAYYNGLKERFKAEILVAKPASVNADEV
VTQ
>Mature_643_residues
MFDFIRKHTKVTMALLFLLIVPSFILFGLDGYNRSREQGVAVARVDGKDIIQSEWDRAHQLEVDRLRASMPSLDAKLLDS
PQARYATLERLVRDRVIAAAADKFKLVISDQRLARELQQSSEIASLRRSDGNLDMERYRQVLGSQGMSPEMFEANVRADL
SNRQVLTGIGASGFSSSSAADLALNAYFEKREIQLARFNAADFAAKLSPTDADLDQFYKANEKLFQAPEQASIEYVMLDV
ETVRKSITINEADLKTYYEQNLQRLSGAEERRASHILITSPKTASAEERQKAKAKAEELLAAVKKSPDTFADVARKNSQD
PGSAPSGGDLDFFARGAMVKPFEDAVFSMKKGDISAVVESEFGYHIIRLTDIKAPKQRSFEEMKPELEADLKKQQAQKKF
SEAAEAFTNGVYEQAGSLKPVAERLKLDIKTASNVTRQPSAGTTGVLANPKFLNALFGPDAVEKKRNTEAIEVAPSQLVS
GRILQYTPARTQPFAEVKDIVRQRWLAQRSAEEARKEGLAKLVAWKAAPASAVLAAPVLVSREQTQNLPVQVIDAALRVD
ASALPVFAGVDLGAQGYAIVKVAKVMPRDARPDAAAKQERNQYAQWWTSAENLAYYNGLKERFKAEILVAKPASVNADEV
VTQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=553, Percent_Identity=24.0506329113924, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1786238, Length=104, Percent_Identity=39.4230769230769, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71036; Mature: 71036

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFIRKHTKVTMALLFLLIVPSFILFGLDGYNRSREQGVAVARVDGKDIIQSEWDRAHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEEEECCHHHHHHHHHHHHH
LEVDRLRASMPSLDAKLLDSPQARYATLERLVRDRVIAAAADKFKLVISDQRLARELQQS
HHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHH
SEIASLRRSDGNLDMERYRQVLGSQGMSPEMFEANVRADLSNRQVLTGIGASGFSSSSAA
HHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHH
DLALNAYFEKREIQLARFNAADFAAKLSPTDADLDQFYKANEKLFQAPEQASIEYVMLDV
HHHHHHHHHHHHHEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEH
ETVRKSITINEADLKTYYEQNLQRLSGAEERRASHILITSPKTASAEERQKAKAKAEELL
HHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHH
AAVKKSPDTFADVARKNSQDPGSAPSGGDLDFFARGAMVKPFEDAVFSMKKGDISAVVES
HHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHEEC
EFGYHIIRLTDIKAPKQRSFEEMKPELEADLKKQQAQKKFSEAAEAFTNGVYEQAGSLKP
CCCEEEEEEECCCCCHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VAERLKLDIKTASNVTRQPSAGTTGVLANPKFLNALFGPDAVEKKRNTEAIEVAPSQLVS
HHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHCCHHHHHHCCCCCEEECHHHHHC
GRILQYTPARTQPFAEVKDIVRQRWLAQRSAEEARKEGLAKLVAWKAAPASAVLAAPVLV
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SREQTQNLPVQVIDAALRVDASALPVFAGVDLGAQGYAIVKVAKVMPRDARPDAAAKQER
CCHHHCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
NQYAQWWTSAENLAYYNGLKERFKAEILVAKPASVNADEVVTQ
HHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCC
>Mature Secondary Structure
MFDFIRKHTKVTMALLFLLIVPSFILFGLDGYNRSREQGVAVARVDGKDIIQSEWDRAHQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEEEECCHHHHHHHHHHHHH
LEVDRLRASMPSLDAKLLDSPQARYATLERLVRDRVIAAAADKFKLVISDQRLARELQQS
HHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHH
SEIASLRRSDGNLDMERYRQVLGSQGMSPEMFEANVRADLSNRQVLTGIGASGFSSSSAA
HHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHH
DLALNAYFEKREIQLARFNAADFAAKLSPTDADLDQFYKANEKLFQAPEQASIEYVMLDV
HHHHHHHHHHHHHEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEH
ETVRKSITINEADLKTYYEQNLQRLSGAEERRASHILITSPKTASAEERQKAKAKAEELL
HHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHH
AAVKKSPDTFADVARKNSQDPGSAPSGGDLDFFARGAMVKPFEDAVFSMKKGDISAVVES
HHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHEEC
EFGYHIIRLTDIKAPKQRSFEEMKPELEADLKKQQAQKKFSEAAEAFTNGVYEQAGSLKP
CCCEEEEEEECCCCCHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
VAERLKLDIKTASNVTRQPSAGTTGVLANPKFLNALFGPDAVEKKRNTEAIEVAPSQLVS
HHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHCCHHHHHHCCCCCEEECHHHHHC
GRILQYTPARTQPFAEVKDIVRQRWLAQRSAEEARKEGLAKLVAWKAAPASAVLAAPVLV
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SREQTQNLPVQVIDAALRVDASALPVFAGVDLGAQGYAIVKVAKVMPRDARPDAAAKQER
CCHHHCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
NQYAQWWTSAENLAYYNGLKERFKAEILVAKPASVNADEVVTQ
HHHHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]