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The map label for this gene is crt [H]

Identifier: 91788883

GI number: 91788883

Start: 3189543

End: 3190352

Strand: Reverse

Name: crt [H]

Synonym: Bpro_3023

Alternate gene names: 91788883

Gene position: 3190352-3189543 (Counterclockwise)

Preceding gene: 91788884

Following gene: 91788882

Centisome position: 61.35

GC content: 63.58

Gene sequence:

>810_bases
ATGTCGACCGTGAGTTATGACTCCCCCACCGAACGCGTGCAGACCTGGCTGGACGCCTCCACGCTGCATATCCGCTTTAA
CAATCCGGCCCGCCACAACGCGCTGTCGGTCGACATGTGGGAGGCCGTCCCGCCCTTGCTGGCACAGGCCGAAACCGACG
ACCGGGTGCGTCTGGTGGTGTTCTCGGGCGCCGGCGAGAAAGCCTTTGTGTCGGGCGCCGACATCTCGCAATTTGAGGAC
ATGCGTGCCGCCCGGGAAGCGGTGACCCGTTATGAGCACATGGCGGAAAACGCCCTGATGAGCATCCACAATTTCAGCAA
GCCCACGCTGTCGTGCATCCGCGGCTTTTGCATCGGCGGCGGTGTGAATGTGGCGATCAGCTGCGACATCCGCATCGCCT
CGACCGATTCGGTGTTTTCGATTCCCGCAGCCCGCTTGGGCCTGGGTTACCGCTACTCGGCCATGAAAAACCTGGTCGAC
CTGATCGGCCCGGGTGCGGCCAAGGACCTGTTCTTCACCGCCCGCAAGATTGACGCCCACGAGGCCAAATCGCTGGGCCT
GATCTCGCGCGCCTGCGCACCCGACGAGCTGCCTGCGCTGCTGGCGGAATACACCTCGGCGCTGGCCGCCAATGCGCCCC
TGACCGTGCGCGCGGGCAAGGCCATCACGGCTGAAATCCTCAAGCCCTCACCCGAGCTGGACCTGGACCTGTGCCAGCGC
CTGATTCGCGGCTGCTTTGACAGCGCCGACTATGCCGAGGGGCGCAAAGCCTTCATGGAAAAACGCAAACCGGCTTTTAC
CGGGAAATAA

Upstream 100 bases:

>100_bases
GTGCCGCGCCGCGCCGTGGCGAGCACACCGAGGAAATCCTGACCGAATTGGGTTTAAGCGCCGGCGATCTGGCGCGCATG
AAATCAACTGGAGTGTATTG

Downstream 100 bases:

>100_bases
CCGGCGCCTGGCCCGGCCACGCCGACACACCCACCCACACCGACACCGAAAGAGAGCAAGCGAATGCAGTCTTACTGGAT
GCAGATGAACGCGGATCACG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSTVSYDSPTERVQTWLDASTLHIRFNNPARHNALSVDMWEAVPPLLAQAETDDRVRLVVFSGAGEKAFVSGADISQFED
MRAAREAVTRYEHMAENALMSIHNFSKPTLSCIRGFCIGGGVNVAISCDIRIASTDSVFSIPAARLGLGYRYSAMKNLVD
LIGPGAAKDLFFTARKIDAHEAKSLGLISRACAPDELPALLAEYTSALAANAPLTVRAGKAITAEILKPSPELDLDLCQR
LIRGCFDSADYAEGRKAFMEKRKPAFTGK

Sequences:

>Translated_269_residues
MSTVSYDSPTERVQTWLDASTLHIRFNNPARHNALSVDMWEAVPPLLAQAETDDRVRLVVFSGAGEKAFVSGADISQFED
MRAAREAVTRYEHMAENALMSIHNFSKPTLSCIRGFCIGGGVNVAISCDIRIASTDSVFSIPAARLGLGYRYSAMKNLVD
LIGPGAAKDLFFTARKIDAHEAKSLGLISRACAPDELPALLAEYTSALAANAPLTVRAGKAITAEILKPSPELDLDLCQR
LIRGCFDSADYAEGRKAFMEKRKPAFTGK
>Mature_268_residues
STVSYDSPTERVQTWLDASTLHIRFNNPARHNALSVDMWEAVPPLLAQAETDDRVRLVVFSGAGEKAFVSGADISQFEDM
RAAREAVTRYEHMAENALMSIHNFSKPTLSCIRGFCIGGGVNVAISCDIRIASTDSVFSIPAARLGLGYRYSAMKNLVDL
IGPGAAKDLFFTARKIDAHEAKSLGLISRACAPDELPALLAEYTSALAANAPLTVRAGKAITAEILKPSPELDLDLCQRL
IRGCFDSADYAEGRKAFMEKRKPAFTGK

Specific function: Unknown

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=251, Percent_Identity=27.0916334661355, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI70995211, Length=216, Percent_Identity=30.5555555555556, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI20127408, Length=174, Percent_Identity=30.4597701149425, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI37594469, Length=129, Percent_Identity=32.5581395348837, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI37594471, Length=129, Percent_Identity=32.5581395348837, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=25.609756097561, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI68989263, Length=172, Percent_Identity=31.9767441860465, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4502327, Length=254, Percent_Identity=26.3779527559055, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87082183, Length=252, Percent_Identity=29.7619047619048, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=26.1992619926199, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=27.1653543307087, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788597, Length=247, Percent_Identity=25.9109311740891, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788682, Length=216, Percent_Identity=28.2407407407407, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790281, Length=183, Percent_Identity=20.2185792349727, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=24.904214559387, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=244, Percent_Identity=27.0491803278689, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=246, Percent_Identity=26.8292682926829, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=260, Percent_Identity=26.1538461538462, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=207, Percent_Identity=25.6038647342995, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=206, Percent_Identity=23.7864077669903, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=187, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=189, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=189, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=189, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=186, Percent_Identity=25.2688172043011, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24653139, Length=281, Percent_Identity=28.8256227758007, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=26.6129032258064, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=26.6129032258064, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920382, Length=284, Percent_Identity=26.7605633802817, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19922422, Length=260, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921000, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654903, Length=177, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583077, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583079, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24650670, Length=188, Percent_Identity=26.063829787234, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21357171, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 29188; Mature: 29056

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVSYDSPTERVQTWLDASTLHIRFNNPARHNALSVDMWEAVPPLLAQAETDDRVRLVV
CCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCEEEEHHHHCCHHHHCCCCCCCEEEEE
FSGAGEKAFVSGADISQFEDMRAAREAVTRYEHMAENALMSIHNFSKPTLSCIRGFCIGG
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GVNVAISCDIRIASTDSVFSIPAARLGLGYRYSAMKNLVDLIGPGAAKDLFFTARKIDAH
CCEEEEEEEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
EAKSLGLISRACAPDELPALLAEYTSALAANAPLTVRAGKAITAEILKPSPELDLDLCQR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCHHHHHH
LIRGCFDSADYAEGRKAFMEKRKPAFTGK
HHHHHCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STVSYDSPTERVQTWLDASTLHIRFNNPARHNALSVDMWEAVPPLLAQAETDDRVRLVV
CCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCEEEEHHHHCCHHHHCCCCCCCEEEEE
FSGAGEKAFVSGADISQFEDMRAAREAVTRYEHMAENALMSIHNFSKPTLSCIRGFCIGG
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
GVNVAISCDIRIASTDSVFSIPAARLGLGYRYSAMKNLVDLIGPGAAKDLFFTARKIDAH
CCEEEEEEEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
EAKSLGLISRACAPDELPALLAEYTSALAANAPLTVRAGKAITAEILKPSPELDLDLCQR
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCHHHHHH
LIRGCFDSADYAEGRKAFMEKRKPAFTGK
HHHHHCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]