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The map label for this gene is hmgA [H]

Identifier: 91788857

GI number: 91788857

Start: 3157323

End: 3158627

Strand: Reverse

Name: hmgA [H]

Synonym: Bpro_2997

Alternate gene names: 91788857

Gene position: 3158627-3157323 (Counterclockwise)

Preceding gene: 91788858

Following gene: 91788856

Centisome position: 60.74

GC content: 65.82

Gene sequence:

>1305_bases
ATGAACACAGACGCCTTGCGCTACCAGTCCGGTTTTGGCAACGAGTTTGTCAGTGAAGCCGTTGCGGGTGCCTTGCCCGA
GGGCCGCAACAGCCCGCAGCGCGCGCCCCATGACCTGTACACCGAGCTGTTGTCGGGCACCGCCTTCACGGCACCGCGCG
CCGAGAATCGCCGTAGCTGGCTGTACCGCCGCCAGCCCTCCGTGGTCAGCGGCGCTTACCAGGCCTATGCACAGCCGCAG
TGGACGACCGGTGCGGCGGGCGGCATGGCCGTTGCGCCCGACCCGCTGCGCTGGAACCCGTTTGCCATCCCGGCCGAGGC
GCTGGACTTTGTGGACGGCATGCGCACCGTGGCGGCCAACGGCGATGCCGAGGCCCAAACCGGCATGGCTGCGCACGTGT
ATGTGGCCAACCGGTCCATGTCGCAACGCGCCATGGTCAATGCCGACGGTGAAATGCTGCTGGTACCGCAGCAGGGCCGG
GTGGTGCTGAAGACGGAACTCGGCCTGCTGGAGGTCAGGCCCGGCGAGGTGGCCGTGGTGCCGCGCGGCATGGCCTTCAG
CGTGGCGCTGCCAGACGGCGCGTCACGCGGCTACGTCTGCGAGAACTACGGCGCGCATTTCCGCCTGCCGGAACTGGGCC
CGATCGGCTCCAATGGCCTGGCCAATGCGCGGGATTTCATGGCGCCCACGGCGGCGTTCGATGACGTGGCAGCCCCCGCC
GGCGGGTTCGACATCATCAAGAAGTATGGCGGCCGCCTGTGGACTGCGAAGCAGCCCGCCAGCCCCTTCAATGTGGTGGC
ATGGCACGGCAACCTGGTGCCCTACAAGTACGACACCGCCCATTTCATGACGATCGGCTCCATCAGTTACGACCATCCGG
ACCCGTCCATTTTCACGGTGCTGACTTCGCCATCGGACACCCCCGGCACGGCCAACTGCGACTTCGTGATCTTCCCGCCG
CGCTGGCTGGTGGCCGAAAACACCTTCCGTCCGCCCTGGTACCACCGCAACCTCATGAGCGAATTCATGGGGCTGGTGTA
TGGCCAGTATGACGCCAAGCCCGAAGGCTTCAAGCCGGGCGGCGCTTCGCTGCACAACTGCATGGTGCCGCACGGACCGG
ACGCCGAGGCCTTTGAGAAAGCCAGCACCGCCGAGCTGGCGCCGCACAAGCTGGACAACACGCTGGCCTTCATGTTTGAA
AGCCGCTACCGCTTTATTCCCACCGCATTTGCCATGGAAGGCGGTGCGCTGGATACCGGTTACCTCAGCTGCTGGGCGGG
CCTCAAGGATCAATTCAAGCCCTGA

Upstream 100 bases:

>100_bases
CAGCGATTTTTTCGACCGCCTGATCGATCAGGCCCGGGCCAATGGCGACGCGGCTGATGCTGATGGCGCCGATGACTGAA
ATTTACTTTGGAGAGATGCG

Downstream 100 bases:

>100_bases
GTTTTCGCACGGCTCATCACCCCTTTCACGGCGCCCTGGCGTCAAGGATTTGCACCATGAATGATTCGCTCAATGCCACC
CACGACCCGGCGCTTCGCAG

Product: homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNTDALRYQSGFGNEFVSEAVAGALPEGRNSPQRAPHDLYTELLSGTAFTAPRAENRRSWLYRRQPSVVSGAYQAYAQPQ
WTTGAAGGMAVAPDPLRWNPFAIPAEALDFVDGMRTVAANGDAEAQTGMAAHVYVANRSMSQRAMVNADGEMLLVPQQGR
VVLKTELGLLEVRPGEVAVVPRGMAFSVALPDGASRGYVCENYGAHFRLPELGPIGSNGLANARDFMAPTAAFDDVAAPA
GGFDIIKKYGGRLWTAKQPASPFNVVAWHGNLVPYKYDTAHFMTIGSISYDHPDPSIFTVLTSPSDTPGTANCDFVIFPP
RWLVAENTFRPPWYHRNLMSEFMGLVYGQYDAKPEGFKPGGASLHNCMVPHGPDAEAFEKASTAELAPHKLDNTLAFMFE
SRYRFIPTAFAMEGGALDTGYLSCWAGLKDQFKP

Sequences:

>Translated_434_residues
MNTDALRYQSGFGNEFVSEAVAGALPEGRNSPQRAPHDLYTELLSGTAFTAPRAENRRSWLYRRQPSVVSGAYQAYAQPQ
WTTGAAGGMAVAPDPLRWNPFAIPAEALDFVDGMRTVAANGDAEAQTGMAAHVYVANRSMSQRAMVNADGEMLLVPQQGR
VVLKTELGLLEVRPGEVAVVPRGMAFSVALPDGASRGYVCENYGAHFRLPELGPIGSNGLANARDFMAPTAAFDDVAAPA
GGFDIIKKYGGRLWTAKQPASPFNVVAWHGNLVPYKYDTAHFMTIGSISYDHPDPSIFTVLTSPSDTPGTANCDFVIFPP
RWLVAENTFRPPWYHRNLMSEFMGLVYGQYDAKPEGFKPGGASLHNCMVPHGPDAEAFEKASTAELAPHKLDNTLAFMFE
SRYRFIPTAFAMEGGALDTGYLSCWAGLKDQFKP
>Mature_434_residues
MNTDALRYQSGFGNEFVSEAVAGALPEGRNSPQRAPHDLYTELLSGTAFTAPRAENRRSWLYRRQPSVVSGAYQAYAQPQ
WTTGAAGGMAVAPDPLRWNPFAIPAEALDFVDGMRTVAANGDAEAQTGMAAHVYVANRSMSQRAMVNADGEMLLVPQQGR
VVLKTELGLLEVRPGEVAVVPRGMAFSVALPDGASRGYVCENYGAHFRLPELGPIGSNGLANARDFMAPTAAFDDVAAPA
GGFDIIKKYGGRLWTAKQPASPFNVVAWHGNLVPYKYDTAHFMTIGSISYDHPDPSIFTVLTSPSDTPGTANCDFVIFPP
RWLVAENTFRPPWYHRNLMSEFMGLVYGQYDAKPEGFKPGGASLHNCMVPHGPDAEAFEKASTAELAPHKLDNTLAFMFE
SRYRFIPTAFAMEGGALDTGYLSCWAGLKDQFKP

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

Organism=Homo sapiens, GI115527117, Length=438, Percent_Identity=52.5114155251142, Blast_Score=465, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17507969, Length=437, Percent_Identity=53.3180778032037, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24583650, Length=434, Percent_Identity=50.6912442396313, Blast_Score=437, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR022950 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: =1.13.11.5 [H]

Molecular weight: Translated: 47118; Mature: 47118

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDALRYQSGFGNEFVSEAVAGALPEGRNSPQRAPHDLYTELLSGTAFTAPRAENRRSW
CCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCHHHH
LYRRQPSVVSGAYQAYAQPQWTTGAAGGMAVAPDPLRWNPFAIPAEALDFVDGMRTVAAN
HHHCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHEEECC
GDAEAQTGMAAHVYVANRSMSQRAMVNADGEMLLVPQQGRVVLKTELGLLEVRPGEVAVV
CCCCHHCCCEEEEEEECCCCCHHEEECCCCCEEEEECCCCEEEEECCCEEEECCCCEEEE
PRGMAFSVALPDGASRGYVCENYGAHFRLPELGPIGSNGLANARDFMAPTAAFDDVAAPA
ECCEEEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCC
GGFDIIKKYGGRLWTAKQPASPFNVVAWHGNLVPYKYDTAHFMTIGSISYDHPDPSIFTV
CCHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCEEECCEEEEEEECEECCCCCCCEEEE
LTSPSDTPGTANCDFVIFPPRWLVAENTFRPPWYHRNLMSEFMGLVYGQYDAKPEGFKPG
EECCCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GASLHNCMVPHGPDAEAFEKASTAELAPHKLDNTLAFMFESRYRFIPTAFAMEGGALDTG
CCCHHHCCCCCCCCHHHHHHCCHHHCCCHHHCCHHEEEECCCCCCCCHHEEECCCCCCCH
YLSCWAGLKDQFKP
HHHHHHCCHHCCCC
>Mature Secondary Structure
MNTDALRYQSGFGNEFVSEAVAGALPEGRNSPQRAPHDLYTELLSGTAFTAPRAENRRSW
CCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEECCCCCCCHHHH
LYRRQPSVVSGAYQAYAQPQWTTGAAGGMAVAPDPLRWNPFAIPAEALDFVDGMRTVAAN
HHHCCCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHEEECC
GDAEAQTGMAAHVYVANRSMSQRAMVNADGEMLLVPQQGRVVLKTELGLLEVRPGEVAVV
CCCCHHCCCEEEEEEECCCCCHHEEECCCCCEEEEECCCCEEEEECCCEEEECCCCEEEE
PRGMAFSVALPDGASRGYVCENYGAHFRLPELGPIGSNGLANARDFMAPTAAFDDVAAPA
ECCEEEEEECCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHCCCC
GGFDIIKKYGGRLWTAKQPASPFNVVAWHGNLVPYKYDTAHFMTIGSISYDHPDPSIFTV
CCHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCEEECCEEEEEEECEECCCCCCCEEEE
LTSPSDTPGTANCDFVIFPPRWLVAENTFRPPWYHRNLMSEFMGLVYGQYDAKPEGFKPG
EECCCCCCCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GASLHNCMVPHGPDAEAFEKASTAELAPHKLDNTLAFMFESRYRFIPTAFAMEGGALDTG
CCCHHHCCCCCCCCHHHHHHCCHHHCCCHHHCCHHEEEECCCCCCCCHHEEECCCCCCCH
YLSCWAGLKDQFKP
HHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA