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The map label for this gene is CYP167A1 [H]

Identifier: 91788669

GI number: 91788669

Start: 2950945

End: 2952120

Strand: Reverse

Name: CYP167A1 [H]

Synonym: Bpro_2807

Alternate gene names: 91788669

Gene position: 2952120-2950945 (Counterclockwise)

Preceding gene: 91788671

Following gene: 91788668

Centisome position: 56.77

GC content: 65.82

Gene sequence:

>1176_bases
GTGAGTGACGGCGTTCTTCCACAGCCTGGCAACCCGATCGAGGCGGTCACCCATGTCGACCCGTACCCCTACTACCGGCA
GTTGCGGGAACAGCGGCCGCTGTATTTTGATGAAGGCCTGAAGCTCTGGGTGGCCAGCAGCCATTCCGTGATAGATGAGG
CCTTTCACAACGTGGCGCTGCGTGTGCGTCCGCCGGCAGAGCCGGTGCCCCAGGCCCTGCTGGGTACAGCAGCGGGCGAG
GTTTTTGCCCAGCTGGTACGCATGACGGACGGTGAATTTCACGCAGTCCACAAGCCCGCGGTGGAGCAAGCTGCGCGCCG
CTGGAGCCTGGCCGATGTGACGCGGGCCAGCGAAGCGGCTGCAAGGGATCTGTTTGCCGCCGGGCCGCCCCAAGGCAAAC
ATGGCCCCCTTGGGGGGCAGCGTAGCGTGGGGGCCAAATTTCGGTGTCTGACCGTCAACGACCTCATGGGTGTGCTGCCG
GTGCAGGCTATGGCGCGCCTGCTGGGCCTGCCTGACGGCTTGCTTGACGACTCCTGCCGTTGGGTCCGGCAGTTCGTGCA
GGGCATTGCACCTGGCGCGTCGACGCAGGCCGTGGCGCTGGCGGCTGGCGCAGCCGAGGCCCTGATGGACCAGGGCCGGG
CGCTGGGTTTGTCGACTGTGCAGGCGGCCAACCGCATCGCCTTCATGCAGCAGTCGCTCGATGCCACAGCGGGGCTGATG
GGGCATACCGTGCTGATGCTCGCGCAATACCCCGACCTTGCGCTCCTGGCTGATCAGTCGCCGCAAGCCATGCGCGGGTT
CGTCGCCGAGGTCGAGCGCCATCAAGCGCCTATCCAGAACACGCGGCGCTTTGCCGCCGATCCCGTGGTGCTGGCGGGCC
AGTCGATCGAGGCAGGGCAGGGCGTGGTGCTCGTGCTGGCCAGCGCCAACCGCGACGGGCTACTGAATCCCAGGCCCGAC
CAGTTCGATCCGCAGCGCGGCGAACGCCGCAGCATGGGCTTCGGTGCAGGCGCTCATGCCTGCCCCGGCGCCGCAATCGC
CATCGAAATGGTAGCTGCTTGTATCCAATGGATGCGGGCTACAAGCCAATTTGATGGTTGTTTTGGAGCTCTGGCGGGTT
TCTGGCCGCTGGCCAACGCCCGCATACCCTTATTTGCAAGCAGAAAGGAAGCATGA

Upstream 100 bases:

>100_bases
ATGCGTGGGCAGATTGACCAGTTCCACCACGAAGCCGGCGCAGAATGTTCCATCGCCAACCCGGTCAAAATGGAAGCGCG
TGGTGAGCCGGCGTCTGCCC

Downstream 100 bases:

>100_bases
TGGTCTCCGTGATTTTCGAAGTCTGGCCCGATCCGGCGCACCGCGAGGGCTACCTGAACTGGGCGGCCGAACTCAAGAGC
GAGCTGGTGAAGATGGACGG

Product: putative cytochrome p450 oxidoreductase

Products: NA

Alternate protein names: Cytochrome P450epoK; Epothilone epoxidase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSDGVLPQPGNPIEAVTHVDPYPYYRQLREQRPLYFDEGLKLWVASSHSVIDEAFHNVALRVRPPAEPVPQALLGTAAGE
VFAQLVRMTDGEFHAVHKPAVEQAARRWSLADVTRASEAAARDLFAAGPPQGKHGPLGGQRSVGAKFRCLTVNDLMGVLP
VQAMARLLGLPDGLLDDSCRWVRQFVQGIAPGASTQAVALAAGAAEALMDQGRALGLSTVQAANRIAFMQQSLDATAGLM
GHTVLMLAQYPDLALLADQSPQAMRGFVAEVERHQAPIQNTRRFAADPVVLAGQSIEAGQGVVLVLASANRDGLLNPRPD
QFDPQRGERRSMGFGAGAHACPGAAIAIEMVAACIQWMRATSQFDGCFGALAGFWPLANARIPLFASRKEA

Sequences:

>Translated_391_residues
MSDGVLPQPGNPIEAVTHVDPYPYYRQLREQRPLYFDEGLKLWVASSHSVIDEAFHNVALRVRPPAEPVPQALLGTAAGE
VFAQLVRMTDGEFHAVHKPAVEQAARRWSLADVTRASEAAARDLFAAGPPQGKHGPLGGQRSVGAKFRCLTVNDLMGVLP
VQAMARLLGLPDGLLDDSCRWVRQFVQGIAPGASTQAVALAAGAAEALMDQGRALGLSTVQAANRIAFMQQSLDATAGLM
GHTVLMLAQYPDLALLADQSPQAMRGFVAEVERHQAPIQNTRRFAADPVVLAGQSIEAGQGVVLVLASANRDGLLNPRPD
QFDPQRGERRSMGFGAGAHACPGAAIAIEMVAACIQWMRATSQFDGCFGALAGFWPLANARIPLFASRKEA
>Mature_390_residues
SDGVLPQPGNPIEAVTHVDPYPYYRQLREQRPLYFDEGLKLWVASSHSVIDEAFHNVALRVRPPAEPVPQALLGTAAGEV
FAQLVRMTDGEFHAVHKPAVEQAARRWSLADVTRASEAAARDLFAAGPPQGKHGPLGGQRSVGAKFRCLTVNDLMGVLPV
QAMARLLGLPDGLLDDSCRWVRQFVQGIAPGASTQAVALAAGAAEALMDQGRALGLSTVQAANRIAFMQQSLDATAGLMG
HTVLMLAQYPDLALLADQSPQAMRGFVAEVERHQAPIQNTRRFAADPVVLAGQSIEAGQGVVLVLASANRDGLLNPRPDQ
FDPQRGERRSMGFGAGAHACPGAAIAIEMVAACIQWMRATSQFDGCFGALAGFWPLANARIPLFASRKEA

Specific function: Involved in the biosynthesis of epothilones, macrolactones which have a narrow anti-fungal spectrum and microtubule-stabilizing activity. Responsible for the epooxidation of epothilones C and D to epothilones A and B, respectively [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 41705; Mature: 41574

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGVLPQPGNPIEAVTHVDPYPYYRQLREQRPLYFDEGLKLWVASSHSVIDEAFHNVAL
CCCCCCCCCCCCCCHHCCCCCCHHHHHHHHCCCCEECCCCEEEEECCHHHHHHHHHCCEE
RVRPPAEPVPQALLGTAAGEVFAQLVRMTDGEFHAVHKPAVEQAARRWSLADVTRASEAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHCCHHHHHHHHHHH
ARDLFAAGPPQGKHGPLGGQRSVGAKFRCLTVNDLMGVLPVQAMARLLGLPDGLLDDSCR
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
WVRQFVQGIAPGASTQAVALAAGAAEALMDQGRALGLSTVQAANRIAFMQQSLDATAGLM
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GHTVLMLAQYPDLALLADQSPQAMRGFVAEVERHQAPIQNTRRFAADPVVLAGQSIEAGQ
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCC
GVVLVLASANRDGLLNPRPDQFDPQRGERRSMGFGAGAHACPGAAIAIEMVAACIQWMRA
CEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TSQFDGCFGALAGFWPLANARIPLFASRKEA
HHHHHHHHHHHHHHHHHCCCCCCEECCCCCC
>Mature Secondary Structure 
SDGVLPQPGNPIEAVTHVDPYPYYRQLREQRPLYFDEGLKLWVASSHSVIDEAFHNVAL
CCCCCCCCCCCCCHHCCCCCCHHHHHHHHCCCCEECCCCEEEEECCHHHHHHHHHCCEE
RVRPPAEPVPQALLGTAAGEVFAQLVRMTDGEFHAVHKPAVEQAARRWSLADVTRASEAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHCCHHHHHHHHHHH
ARDLFAAGPPQGKHGPLGGQRSVGAKFRCLTVNDLMGVLPVQAMARLLGLPDGLLDDSCR
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
WVRQFVQGIAPGASTQAVALAAGAAEALMDQGRALGLSTVQAANRIAFMQQSLDATAGLM
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GHTVLMLAQYPDLALLADQSPQAMRGFVAEVERHQAPIQNTRRFAADPVVLAGQSIEAGQ
HHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCC
GVVLVLASANRDGLLNPRPDQFDPQRGERRSMGFGAGAHACPGAAIAIEMVAACIQWMRA
CEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TSQFDGCFGALAGFWPLANARIPLFASRKEA
HHHHHHHHHHHHHHHHHCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10662695; 10831849; 10649995 [H]