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The map label for this gene is coaD [H]

Identifier: 91787178

GI number: 91787178

Start: 1324595

End: 1325113

Strand: Direct

Name: coaD [H]

Synonym: Bpro_1282

Alternate gene names: 91787178

Gene position: 1324595-1325113 (Clockwise)

Preceding gene: 91787177

Following gene: 91787179

Centisome position: 25.47

GC content: 63.97

Gene sequence:

>519_bases
ATGCCCGCCACCCCGCCGCCAACGCCACGCATTGCTGTTTATTCCGGCACGTTTGACCCTTTCACGCTCGGCCATGACGA
CGTGGTGCGCCGCGCCGGCAAGCTGTTTGACCAGATCATCATTGCGGTCGCTGCGGCCCACCACAAGAAAACCCTGTTCC
CGCTGCAGGACCGTGTGGAGCAGGCGCAGGCGGCCACCCGCGACATCGTCGGCGTGAGGGTGCTGCCCTTTGACGGGTTG
ATCATGGATTTTTGCGCCGAGCACGGCGCCAGCGCGGTGTTGCGCGGGGTTCGCAACGTGACGGATTTTGATTACGAAGC
GCAAATGGCAGCCATGAATCGCAAGCTCCAGCCGCAGGTGGAGACCGTCTTTTTGCTGCCCGAGGCGTCGCTGCAATGCA
TCAGCAGCACGCTGGTGCGCGAGATCAGCAAGCTGGGCGGAGATGTCCGCCAGATGGTGAGTCCGGCGGTGGCTGCGGCC
TTGGGTGCCGCGCATGCGGCAGGATCGAAAGGAGGCTGA

Upstream 100 bases:

>100_bases
TCGACAGTTGAGGCGCCGGCTGGCCGCCAAGGCAGGGCGGCTGCGGCCCTGTTTGGCTTGGGGTTACGCGCGCCCGAGGC
CGGCGGGGCATAATTCCCCC

Downstream 100 bases:

>100_bases
ACATGGCCTTGATGATTACCGACGAGTGCATCAACTGCGACGTGTGCGAGCCCGAATGCCCCAACCAGGCAATTTACCTG
GGCAAGGAAATCTATGAGAT

Product: coenzyme A biosynthesis protein

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MPATPPPTPRIAVYSGTFDPFTLGHDDVVRRAGKLFDQIIIAVAAAHHKKTLFPLQDRVEQAQAATRDIVGVRVLPFDGL
IMDFCAEHGASAVLRGVRNVTDFDYEAQMAAMNRKLQPQVETVFLLPEASLQCISSTLVREISKLGGDVRQMVSPAVAAA
LGAAHAAGSKGG

Sequences:

>Translated_172_residues
MPATPPPTPRIAVYSGTFDPFTLGHDDVVRRAGKLFDQIIIAVAAAHHKKTLFPLQDRVEQAQAATRDIVGVRVLPFDGL
IMDFCAEHGASAVLRGVRNVTDFDYEAQMAAMNRKLQPQVETVFLLPEASLQCISSTLVREISKLGGDVRQMVSPAVAAA
LGAAHAAGSKGG
>Mature_171_residues
PATPPPTPRIAVYSGTFDPFTLGHDDVVRRAGKLFDQIIIAVAAAHHKKTLFPLQDRVEQAQAATRDIVGVRVLPFDGLI
MDFCAEHGASAVLRGVRNVTDFDYEAQMAAMNRKLQPQVETVFLLPEASLQCISSTLVREISKLGGDVRQMVSPAVAAAL
GAAHAAGSKGG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=152, Percent_Identity=45.3947368421053, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18347; Mature: 18216

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATPPPTPRIAVYSGTFDPFTLGHDDVVRRAGKLFDQIIIAVAAAHHKKTLFPLQDRVE
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QAQAATRDIVGVRVLPFDGLIMDFCAEHGASAVLRGVRNVTDFDYEAQMAAMNRKLQPQV
HHHHHHHHHHCEEECCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCE
ETVFLLPEASLQCISSTLVREISKLGGDVRQMVSPAVAAALGAAHAAGSKGG
EEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PATPPPTPRIAVYSGTFDPFTLGHDDVVRRAGKLFDQIIIAVAAAHHKKTLFPLQDRVE
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QAQAATRDIVGVRVLPFDGLIMDFCAEHGASAVLRGVRNVTDFDYEAQMAAMNRKLQPQV
HHHHHHHHHHCEEECCCCHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCE
ETVFLLPEASLQCISSTLVREISKLGGDVRQMVSPAVAAALGAAHAAGSKGG
EEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA