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The map label for this gene is ctaD [H]

Identifier: 91787143

GI number: 91787143

Start: 1291679

End: 1293313

Strand: Direct

Name: ctaD [H]

Synonym: Bpro_1246

Alternate gene names: 91787143

Gene position: 1291679-1293313 (Clockwise)

Preceding gene: 91787142

Following gene: 91787144

Centisome position: 24.84

GC content: 60.0

Gene sequence:

>1635_bases
ATGAGTGCAGTTCTAGACCATCACGACCACGCGCATGATGACCACGACCACCATGCCCCGACGGGCTGGCGTCGTTGGGT
ATTCGCGACCAACCACAAGGACATTGGCACGCTGTACCTGCTGTTCAGTTTCTTCATGCTGATGTTTGGTGGCGTGCTGG
CCCTGTTGATTCGCGCTGAACTGTTCCAGCCCGGCCTGCAACTGGTGAACCCTGAACTGTTCAACCAGCTCACGACCATG
CACGGCCTGATCATGGTGTTCGGCGCCATCATGCCGGCCTTCGTGGGTTTCGCGAACTGGATGATTCCGCTGCAGATCGG
TGCGGCCGACATGGCGTTTGCCCGCATGAACAACTTCAGCTTCTGGCTGATGATTCCTGCCGGCCTGATGCTGGCCACCT
CGTTTTTCATGCCGGGCGGTGCACCCGCTGCCGGCTGGACGCTCTACGCGCCGCTGACGCTGCAGATGGGGCCGTCCATG
GATGCCGGTATTTTTGCGATGCACATTCTGGGCGCTTCGTCCATCATGGGCTCGATCAACATCATCGTGACCATCCTGAA
CATGCGCGCACCCGGCATGACGCTGATGAAGATGCCGATGTTCTGCTGGACCTGGCTGATCACCGCCTACCTGCTGATCG
CCGTGATGCCCGTGCTGGCCGGCGCCATCACCATGACGCTGACGGATCGCCACTTTGGCACCAGCTTCTTCAACCCCGCC
GGCGGCGGTGACCCGGTGATGTACCAGCATATCTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATGATTCTGCCGGC
CTTCGGCATCATCAGCCAGATCATCCCCGCGTTCTCGCGCAAGCGCTTGTTCGGCTACGCCTCGATGGTGTATGCCACCG
GCTCCATCGCGATCCTGAGCTTTGTCGTGTGGGCGCACCACATGTTCACCACCGGCATGCCCGTGACCGGCCAGCTGTTC
TTCATGTACTCGACCATGCTGATCGCGGTGCCCACCGGCGTGAAAGTGTTCAACTGGATTGCCACCATGTGGAAGGGCTC
GATGACGTTCGAGACGCCCATGCTGTTTGCCGTCGGTTTCATCTTCGTGTTCACCATCGGTGGCCTGACGGGTGTGATTT
TGTCGGTCGCGCCGATTGACACCCAGCTGCAGGACACGTACTACGTGGTGGCCCACTTCCACTACGTGCTGGTGGCCGGT
TCGCTGTACGCCCTGTTTGCCGGTTACTACTACTGGTCGCCCAAGTGGACCGGCGTGATGTACAACGAAACCCGCGGCAA
GATCCACTTCTGGTGGTCGCTGATTTCCTTTAACGTGACATTCTTCCCGATGCACTTCCTGGGCCTTGCCGGCATGCCGC
GCCGCTATGCCGACTACCCGATGCAGTTTGCCGACTTCAACGCAATTGCCACCGTGGGAGCCTTCTTCTTCGGTGTGGCA
CAGGTGTACTTCTTCCTGTTCATCGTGGTGCCCACGATGCGCGGCCAAGGCGCACCCGCCAGGCAGAACCCCTGGGTTGA
CGAGGGAGGCAAAGGCGCTGAAGGCCTGGAGTGGGAAGTCCCGTCGCCAGCTCCTTTTCACACCTTTGAAACCCCTCCCA
AGCTGGATGCCACGGCAACCCGCGTGATTGGTTGA

Upstream 100 bases:

>100_bases
CCGCGGGCAGGTCGTCCTGCCCCAAATCCCCGATACCGCAAGACCATTTCGTCAGCCGTAAAGACAAAGCTACAGGCACA
AGCCACCAAAGGAAGCCAAG

Downstream 100 bases:

>100_bases
ACCACCCGATAACCCGATAGCGCACGATGACACCTGACCAAAAGAAAAGCAATTTGCGGCTGGCACTGATCCTGGCTTCG
GTCGCGCTCGTCTTTTTTGC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSAVLDHHDHAHDDHDHHAPTGWRRWVFATNHKDIGTLYLLFSFFMLMFGGVLALLIRAELFQPGLQLVNPELFNQLTTM
HGLIMVFGAIMPAFVGFANWMIPLQIGAADMAFARMNNFSFWLMIPAGLMLATSFFMPGGAPAAGWTLYAPLTLQMGPSM
DAGIFAMHILGASSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFGTSFFNPA
GGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIIPAFSRKRLFGYASMVYATGSIAILSFVVWAHHMFTTGMPVTGQLF
FMYSTMLIAVPTGVKVFNWIATMWKGSMTFETPMLFAVGFIFVFTIGGLTGVILSVAPIDTQLQDTYYVVAHFHYVLVAG
SLYALFAGYYYWSPKWTGVMYNETRGKIHFWWSLISFNVTFFPMHFLGLAGMPRRYADYPMQFADFNAIATVGAFFFGVA
QVYFFLFIVVPTMRGQGAPARQNPWVDEGGKGAEGLEWEVPSPAPFHTFETPPKLDATATRVIG

Sequences:

>Translated_544_residues
MSAVLDHHDHAHDDHDHHAPTGWRRWVFATNHKDIGTLYLLFSFFMLMFGGVLALLIRAELFQPGLQLVNPELFNQLTTM
HGLIMVFGAIMPAFVGFANWMIPLQIGAADMAFARMNNFSFWLMIPAGLMLATSFFMPGGAPAAGWTLYAPLTLQMGPSM
DAGIFAMHILGASSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFGTSFFNPA
GGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIIPAFSRKRLFGYASMVYATGSIAILSFVVWAHHMFTTGMPVTGQLF
FMYSTMLIAVPTGVKVFNWIATMWKGSMTFETPMLFAVGFIFVFTIGGLTGVILSVAPIDTQLQDTYYVVAHFHYVLVAG
SLYALFAGYYYWSPKWTGVMYNETRGKIHFWWSLISFNVTFFPMHFLGLAGMPRRYADYPMQFADFNAIATVGAFFFGVA
QVYFFLFIVVPTMRGQGAPARQNPWVDEGGKGAEGLEWEVPSPAPFHTFETPPKLDATATRVIG
>Mature_543_residues
SAVLDHHDHAHDDHDHHAPTGWRRWVFATNHKDIGTLYLLFSFFMLMFGGVLALLIRAELFQPGLQLVNPELFNQLTTMH
GLIMVFGAIMPAFVGFANWMIPLQIGAADMAFARMNNFSFWLMIPAGLMLATSFFMPGGAPAAGWTLYAPLTLQMGPSMD
AGIFAMHILGASSIMGSINIIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFGTSFFNPAG
GGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIIPAFSRKRLFGYASMVYATGSIAILSFVVWAHHMFTTGMPVTGQLFF
MYSTMLIAVPTGVKVFNWIATMWKGSMTFETPMLFAVGFIFVFTIGGLTGVILSVAPIDTQLQDTYYVVAHFHYVLVAGS
LYALFAGYYYWSPKWTGVMYNETRGKIHFWWSLISFNVTFFPMHFLGLAGMPRRYADYPMQFADFNAIATVGAFFFGVAQ
VYFFLFIVVPTMRGQGAPARQNPWVDEGGKGAEGLEWEVPSPAPFHTFETPPKLDATATRVIG

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=514, Percent_Identity=50.9727626459144, Blast_Score=476, Evalue=1e-134,
Organism=Escherichia coli, GI1786634, Length=521, Percent_Identity=40.3071017274472, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6226519, Length=533, Percent_Identity=47.6547842401501, Blast_Score=485, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=50, Blast_Score=318, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=47.3895582329317, Blast_Score=209, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60676; Mature: 60545

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVLDHHDHAHDDHDHHAPTGWRRWVFATNHKDIGTLYLLFSFFMLMFGGVLALLIRAE
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LFQPGLQLVNPELFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGAADMAFARMNNFS
HHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHCCCE
FWLMIPAGLMLATSFFMPGGAPAAGWTLYAPLTLQMGPSMDAGIFAMHILGASSIMGSIN
EEEEEHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHE
IIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFGTSFFNPA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCC
GGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIIPAFSRKRLFGYASMVYATGSIAILS
CCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FVVWAHHMFTTGMPVTGQLFFMYSTMLIAVPTGVKVFNWIATMWKGSMTFETPMLFAVGF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
IFVFTIGGLTGVILSVAPIDTQLQDTYYVVAHFHYVLVAGSLYALFAGYYYWSPKWTGVM
HHHHHHHHHHHHHHEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEE
YNETRGKIHFWWSLISFNVTFFPMHFLGLAGMPRRYADYPMQFADFNAIATVGAFFFGVA
EECCCCCEEEEEEEEHHCHHHHHHHHHHCCCCCCHHHCCCCCHHCHHHHHHHHHHHHHHH
QVYFFLFIVVPTMRGQGAPARQNPWVDEGGKGAEGLEWEVPSPAPFHTFETPPKLDATAT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHH
RVIG
HCCC
>Mature Secondary Structure 
SAVLDHHDHAHDDHDHHAPTGWRRWVFATNHKDIGTLYLLFSFFMLMFGGVLALLIRAE
CCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LFQPGLQLVNPELFNQLTTMHGLIMVFGAIMPAFVGFANWMIPLQIGAADMAFARMNNFS
HHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHCCCE
FWLMIPAGLMLATSFFMPGGAPAAGWTLYAPLTLQMGPSMDAGIFAMHILGASSIMGSIN
EEEEEHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHE
IIVTILNMRAPGMTLMKMPMFCWTWLITAYLLIAVMPVLAGAITMTLTDRHFGTSFFNPA
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCC
GGGDPVMYQHIFWFFGHPEVYIMILPAFGIISQIIPAFSRKRLFGYASMVYATGSIAILS
CCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FVVWAHHMFTTGMPVTGQLFFMYSTMLIAVPTGVKVFNWIATMWKGSMTFETPMLFAVGF
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
IFVFTIGGLTGVILSVAPIDTQLQDTYYVVAHFHYVLVAGSLYALFAGYYYWSPKWTGVM
HHHHHHHHHHHHHHEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEE
YNETRGKIHFWWSLISFNVTFFPMHFLGLAGMPRRYADYPMQFADFNAIATVGAFFFGVA
EECCCCCEEEEEEEEHHCHHHHHHHHHHCCCCCCHHHCCCCCHHCHHHHHHHHHHHHHHH
QVYFFLFIVVPTMRGQGAPARQNPWVDEGGKGAEGLEWEVPSPAPFHTFETPPKLDATAT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHH
RVIG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]