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The map label for this gene is lolC [H]

Identifier: 91786914

GI number: 91786914

Start: 1031131

End: 1032387

Strand: Direct

Name: lolC [H]

Synonym: Bpro_1014

Alternate gene names: 91786914

Gene position: 1031131-1032387 (Clockwise)

Preceding gene: 91786899

Following gene: 91786915

Centisome position: 19.83

GC content: 64.28

Gene sequence:

>1257_bases
ATGCAAATCCCCTATGAGCTGATTTTGGGCTGGCGCTACACCCGCGCTGGCCGGGCCACACGGCGCAACGGCTTTATCTC
CTTTATTTCGGGCGTGTCCATGCTGGGCATTGCGCTGGGCGTGGCCGCGCTGATCATTGTGCTGAGCGTGATGAACGGCT
TCCAGAAGGAAGTCCGCGACCGCATGCTGGGCGTGATCTCCCACATCGAGGTGTTCGCGCCCAATGGCGCCGCGCTGCCC
GACCCGCAGAAAACCCTGGCCGAGATCAAGGCCAACCCGCAAGTGGTGGGCGCCGCCACCTTCATCGCCGCGCAGGCCCT
GCTGGCGCGCGGCGAAGACATGAAGGGCACGCTGGTGCGCGGCATCGATCCGGCGCTGGAAGGGCAGGTCACCGACCTCG
CGGTGCAACTGAAAGACACGGCCTTTCCCAAACTGGTGAGCGGCGGCTTTGGCGTGGTGCTGGGCGGCGAACTGGCACGC
TCCATGGGTGTGCGTGAGGGCGACACCGTCACGCTGATCGCGCCCAGCGGCCAGGTCACGCCCGCCGGCGTGGTGCCGCG
CCTCAAGCAAATGACGGTGGTGGGCACCTTCGACTCCGGCCACTTTGAATACGACTCGGCGCTCGTCATGCTGCACCAGG
ACGACGCCGCCCGGATTTTCCGGCTGGAGGGCCCGACCGGCATCCGCATCAAGCTGAAAGACCTGCACCAGGCGCGCGAA
GTCGCGCTGGAGCTGTCCAGAAGCCTGACCGGCGACCTGCTGATTCGCGACTGGACGCGGCAGAACAAAACCTGGTTTGC
GGCGGTGCAGCTTGAAAAACGCATGATGTTCATCATCCTGACGCTGATCGTGGCGGTGGCGGCCTTCAACCTCGTCAGCA
CGCTGGTGATGACGGTGACCGACAAGCGCGCCGACATCGCCATCCTGCGCACCCTGGGCGCCAGCCCCCAGAGCATCATG
AAGATATTCATGGTGCAAGGCGCCCTGGTCGGCGTGATCGGCACCTTCTCGGGCCTGCTGCTCGGCCTGGGCATTGCCTT
GAATATTGACGTCATCGTGCCGGCGCTGGAGCGGCTGCTCAATGCGAGCTTCCTGCCCAAAGACATCTACCTGATCAGCC
GCATGCCCAGCGAGCCGCAGTACGCCGACATCATGCCGATTGTCGTCATCTCACTGGTACTGGCATTTCTGGCCACCATC
TACCCCAGCTGGCGCGCCAGCCAGGTGAACCCGGCCGAGGCCCTGCGTTATGAATAA

Upstream 100 bases:

>100_bases
AGGCCGCAAACGGAATCAGCAGGTGAGGGGGTGCGCAAGCTGGCGGGGATGAGGAAGGGGCGGGCATGGGGCTATTGTCC
GGGATGCAACAATACCGGTC

Downstream 100 bases:

>100_bases
AGACAACATGGATTCACTCCGCGAGGCCTCGCTCCCCAAGGCTTCACCCCCCGGCGCTTCACTTCCCGGGGCTTCACTCC
CTCTCCCCCTGGGAGAGGGC

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MQIPYELILGWRYTRAGRATRRNGFISFISGVSMLGIALGVAALIIVLSVMNGFQKEVRDRMLGVISHIEVFAPNGAALP
DPQKTLAEIKANPQVVGAATFIAAQALLARGEDMKGTLVRGIDPALEGQVTDLAVQLKDTAFPKLVSGGFGVVLGGELAR
SMGVREGDTVTLIAPSGQVTPAGVVPRLKQMTVVGTFDSGHFEYDSALVMLHQDDAARIFRLEGPTGIRIKLKDLHQARE
VALELSRSLTGDLLIRDWTRQNKTWFAAVQLEKRMMFIILTLIVAVAAFNLVSTLVMTVTDKRADIAILRTLGASPQSIM
KIFMVQGALVGVIGTFSGLLLGLGIALNIDVIVPALERLLNASFLPKDIYLISRMPSEPQYADIMPIVVISLVLAFLATI
YPSWRASQVNPAEALRYE

Sequences:

>Translated_418_residues
MQIPYELILGWRYTRAGRATRRNGFISFISGVSMLGIALGVAALIIVLSVMNGFQKEVRDRMLGVISHIEVFAPNGAALP
DPQKTLAEIKANPQVVGAATFIAAQALLARGEDMKGTLVRGIDPALEGQVTDLAVQLKDTAFPKLVSGGFGVVLGGELAR
SMGVREGDTVTLIAPSGQVTPAGVVPRLKQMTVVGTFDSGHFEYDSALVMLHQDDAARIFRLEGPTGIRIKLKDLHQARE
VALELSRSLTGDLLIRDWTRQNKTWFAAVQLEKRMMFIILTLIVAVAAFNLVSTLVMTVTDKRADIAILRTLGASPQSIM
KIFMVQGALVGVIGTFSGLLLGLGIALNIDVIVPALERLLNASFLPKDIYLISRMPSEPQYADIMPIVVISLVLAFLATI
YPSWRASQVNPAEALRYE
>Mature_418_residues
MQIPYELILGWRYTRAGRATRRNGFISFISGVSMLGIALGVAALIIVLSVMNGFQKEVRDRMLGVISHIEVFAPNGAALP
DPQKTLAEIKANPQVVGAATFIAAQALLARGEDMKGTLVRGIDPALEGQVTDLAVQLKDTAFPKLVSGGFGVVLGGELAR
SMGVREGDTVTLIAPSGQVTPAGVVPRLKQMTVVGTFDSGHFEYDSALVMLHQDDAARIFRLEGPTGIRIKLKDLHQARE
VALELSRSLTGDLLIRDWTRQNKTWFAAVQLEKRMMFIILTLIVAVAAFNLVSTLVMTVTDKRADIAILRTLGASPQSIM
KIFMVQGALVGVIGTFSGLLLGLGIALNIDVIVPALERLLNASFLPKDIYLISRMPSEPQYADIMPIVVISLVLAFLATI
YPSWRASQVNPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=417, Percent_Identity=31.6546762589928, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787360, Length=421, Percent_Identity=35.6294536817102, Blast_Score=208, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45246; Mature: 45246

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIPYELILGWRYTRAGRATRRNGFISFISGVSMLGIALGVAALIIVLSVMNGFQKEVRD
CCCCHHHHEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLGVISHIEVFAPNGAALPDPQKTLAEIKANPQVVGAATFIAAQALLARGEDMKGTLVR
HHHHHHHHHHEECCCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHH
GIDPALEGQVTDLAVQLKDTAFPKLVSGGFGVVLGGELARSMGVREGDTVTLIAPSGQVT
CCCHHHCCCHHHHEEEEHHCCCHHHHCCCCCEEECHHHHHHCCCCCCCEEEEECCCCCCC
PAGVVPRLKQMTVVGTFDSGHFEYDSALVMLHQDDAARIFRLEGPTGIRIKLKDLHQARE
CCHHCCHHHHEEEEEEECCCCEEECCEEEEEEECCCEEEEEECCCCCEEEEHHHHHHHHH
VALELSRSLTGDLLIRDWTRQNKTWFAAVQLEKRMMFIILTLIVAVAAFNLVSTLVMTVT
HHHHHHHCCCCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DKRADIAILRTLGASPQSIMKIFMVQGALVGVIGTFSGLLLGLGIALNIDVIVPALERLL
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
NASFLPKDIYLISRMPSEPQYADIMPIVVISLVLAFLATIYPSWRASQVNPAEALRYE
CCCCCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MQIPYELILGWRYTRAGRATRRNGFISFISGVSMLGIALGVAALIIVLSVMNGFQKEVRD
CCCCHHHHEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLGVISHIEVFAPNGAALPDPQKTLAEIKANPQVVGAATFIAAQALLARGEDMKGTLVR
HHHHHHHHHHEECCCCCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHH
GIDPALEGQVTDLAVQLKDTAFPKLVSGGFGVVLGGELARSMGVREGDTVTLIAPSGQVT
CCCHHHCCCHHHHEEEEHHCCCHHHHCCCCCEEECHHHHHHCCCCCCCEEEEECCCCCCC
PAGVVPRLKQMTVVGTFDSGHFEYDSALVMLHQDDAARIFRLEGPTGIRIKLKDLHQARE
CCHHCCHHHHEEEEEEECCCCEEECCEEEEEEECCCEEEEEECCCCCEEEEHHHHHHHHH
VALELSRSLTGDLLIRDWTRQNKTWFAAVQLEKRMMFIILTLIVAVAAFNLVSTLVMTVT
HHHHHHHCCCCCCEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DKRADIAILRTLGASPQSIMKIFMVQGALVGVIGTFSGLLLGLGIALNIDVIVPALERLL
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHH
NASFLPKDIYLISRMPSEPQYADIMPIVVISLVLAFLATIYPSWRASQVNPAEALRYE
CCCCCCCHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]