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The map label for this gene is fdhB1 [H]

Identifier: 91786840

GI number: 91786840

Start: 959370

End: 959987

Strand: Direct

Name: fdhB1 [H]

Synonym: Bpro_0938

Alternate gene names: 91786840

Gene position: 959370-959987 (Clockwise)

Preceding gene: 91786839

Following gene: 91786841

Centisome position: 18.45

GC content: 62.62

Gene sequence:

>618_bases
ATGGCACGCATGAAATTTGTCTGTGACGCCGAGCGCTGCATCGAATGCAACGGCTGCGTCACCGCCTGTAAAAACGAAAA
CGAAGTCCCGTGGGGCGTCAACCGGCGTCGTGTGGTGACGCTGAACGACGGCGTTCCCGGCGAAAAGTCCATCTCGGTTG
CCTGCATGCATTGCAGCGACGCGCCGTGCATGGCCGTCTGCCCGGTCAACTGTTTTTACCGCACCGACGAAGGTGTGGTG
CTGCACGACAAGGATGTCTGCATCGGCTGCGGTTACTGCTCCTATGCCTGCCCCTTCGGCGCGCCGCAGTTCCCGTCGTC
CGGCACCTTTGGTGTGCGCGGCAAGATGGACAAATGCACCTTTTGCGCGGGTGGCCCCGAAGTCAACGGCAGCCAGGCCG
AATTTGAAAAATACGGCCGCAACCGGCTGGCTGAAGGCAAGTTGCCGGCTTGCGCCGAACAGTGCTCGACCAAGGCCCTG
CTGGCCGGTGATGGCGATGTGGTCGCCGACATCTTCCGCAACCGGGTGGTGCAGCGCGGCAAAGGTGCCGAGGTCTGGGG
CTGGGGAACGGCCTATGGGTCCAGGCAGGCTGGCCAGCCCGCAGGAGGAAAATCATGA

Upstream 100 bases:

>100_bases
GAGGCCCCTGTTGGAGCAGAGCCCCACGCCAGCTTCCGATCGCCCTGAGGTATCGAAGGGTGGGTCAGCCCAGTGGAAAA
ATGATCTTTCAGGAGGCACC

Downstream 100 bases:

>100_bases
GGAGCCTTTTGATGCTCGCCATCGCCATGGCCGGTTTGTCGGCCTGTGGCGAAAAACCGCAAACCCTGGGCGGCGCGAAA
AGCGACGTTCCGCCATTTCA

Product: 4Fe-4S ferredoxin

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MARMKFVCDAERCIECNGCVTACKNENEVPWGVNRRRVVTLNDGVPGEKSISVACMHCSDAPCMAVCPVNCFYRTDEGVV
LHDKDVCIGCGYCSYACPFGAPQFPSSGTFGVRGKMDKCTFCAGGPEVNGSQAEFEKYGRNRLAEGKLPACAEQCSTKAL
LAGDGDVVADIFRNRVVQRGKGAEVWGWGTAYGSRQAGQPAGGKS

Sequences:

>Translated_205_residues
MARMKFVCDAERCIECNGCVTACKNENEVPWGVNRRRVVTLNDGVPGEKSISVACMHCSDAPCMAVCPVNCFYRTDEGVV
LHDKDVCIGCGYCSYACPFGAPQFPSSGTFGVRGKMDKCTFCAGGPEVNGSQAEFEKYGRNRLAEGKLPACAEQCSTKAL
LAGDGDVVADIFRNRVVQRGKGAEVWGWGTAYGSRQAGQPAGGKS
>Mature_204_residues
ARMKFVCDAERCIECNGCVTACKNENEVPWGVNRRRVVTLNDGVPGEKSISVACMHCSDAPCMAVCPVNCFYRTDEGVVL
HDKDVCIGCGYCSYACPFGAPQFPSSGTFGVRGKMDKCTFCAGGPEVNGSQAEFEKYGRNRLAEGKLPACAEQCSTKALL
AGDGDVVADIFRNRVVQRGKGAEVWGWGTAYGSRQAGQPAGGKS

Specific function: This chain is an electron transfer unit containing 18 cysteine residues, 16 of which occur in four clusters [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=172, Percent_Identity=34.3023255813954, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787872, Length=169, Percent_Identity=34.3195266272189, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI226510944, Length=205, Percent_Identity=32.1951219512195, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI2367345, Length=191, Percent_Identity=32.9842931937173, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789370, Length=200, Percent_Identity=28.5, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789079, Length=227, Percent_Identity=28.6343612334802, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082114, Length=180, Percent_Identity=28.3333333333333, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790326, Length=194, Percent_Identity=27.319587628866, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082180, Length=200, Percent_Identity=30.5, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI2367245, Length=178, Percent_Identity=30.8988764044944, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787749, Length=229, Percent_Identity=25.764192139738, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR000813 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: 1.2.1.2

Molecular weight: Translated: 21862; Mature: 21731

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
11.2 %Cys+Met (Translated Protein)
8.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
10.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMKFVCDAERCIECNGCVTACKNENEVPWGVNRRRVVTLNDGVPGEKSISVACMHCSD
CCCCCEEECHHHEEECCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCC
APCMAVCPVNCFYRTDEGVVLHDKDVCIGCGYCSYACPFGAPQFPSSGTFGVRGKMDKCT
CCEEEECCCEEEEECCCCEEEECCCEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCCCEE
FCAGGPEVNGSQAEFEKYGRNRLAEGKLPACAEQCSTKALLAGDGDVVADIFRNRVVQRG
EECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHCC
KGAEVWGWGTAYGSRQAGQPAGGKS
CCCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARMKFVCDAERCIECNGCVTACKNENEVPWGVNRRRVVTLNDGVPGEKSISVACMHCSD
CCCCEEECHHHEEECCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCC
APCMAVCPVNCFYRTDEGVVLHDKDVCIGCGYCSYACPFGAPQFPSSGTFGVRGKMDKCT
CCEEEECCCEEEEECCCCEEEECCCEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCCCEE
FCAGGPEVNGSQAEFEKYGRNRLAEGKLPACAEQCSTKALLAGDGDVVADIFRNRVVQRG
EECCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHCC
KGAEVWGWGTAYGSRQAGQPAGGKS
CCCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1781728; 14500908 [H]